Brian Chen
@drbrianchen
Epidemiology. Epigenetics. Aging. Biomarkers.
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A brilliant opportunity for 3 Post-Doctoral Research Fellows in data science/molecular epidemiology to take up 4-year posts in @MarioniGroup.
We are hiring! 3x 4-year postdoc positions at @EdinUni_IGC as part of a BBSRC-funded grant on omics and healthy ageing. Details here: elxw.fa.em3.oraclecloud.com/hcmUI/Candidat… uoe.sharepoint.com/:w:/s/jobdescr… @genscot & @EdinUniLBC data overview 👇
An unbiased comparison of 14 epigenetic clocks in relation to 10-year onset of 174 disease outcomes in 18,859 individuals. medrxiv.org/content/10.110… Our latest @genscot preprint, with Shiny App showing all of the results: shiny.igc.ed.ac.uk/Epigenetic_Clo…
🚀Excited to share our latest preprint on the Methylation Screening Array (MSA) design to facilitate human EWAS discoveries. MSA leverages previous EWAS, bulk, single-cell WGBS data, and technologies for ultra-high throughput profiling. Checkout details: biorxiv.org/cgi/content/sh…
Huge news. A brief breakdown: -sample costs approximately drop by half, potentially doubling current sample sizes in the pipeline -overlap with EPIC is large (145k), but many new sites, incl. >100K new probes using the latest regulatory and cell type-specific chromatin state…
The NEW Infinium Methylation Screening Array from @illumina is now available! Highlights: ✅Expert-designed content for epidemiological research ✅ Exceptional affordability & scalability to apply epigenetics to population-scale projects ✅Highly precise DNA methylation data
mLiftOver: Harmonizing Data Across Infinium DNA Methylation Platforms biorxiv.org/cgi/content/sh… #bioRxiv
Facing challenges with data harmonization on EPICv2? Our latest preprint introduces mLiftOver, designed for data conversion between HM27/HM450/EPIC and EPICv2, including support for the new MSA array! Details here: biorxiv.org/content/10.110… #genomics #bioinformatics
mLiftOver: Harmonizing Data Across Infinium DNA Methylation Platforms biorxiv.org/cgi/content/sh… #bioRxiv
Harmonize data across different generations of @illumina Infinium DNA Methylation Beadchips (27K vs 450K vs EPIC vs EPICv2)! The field appreciates you, @zhouwanding! biorxiv.org/cgi/content/sh…
Congrats to the 2023 #NIAStartUpChallenge & Accelerator finalists! Proud to serve as an advisor to this diverse group driving innovations in aging.
mLiftOver: Harmonizing Data Across Infinium DNA Methylation Platforms biorxiv.org/cgi/content/sh… #bioRxiv
Our #epigenetics paper in Nature Communications is out with experimental evidence that DNA methylation loss in #aging and #cancer is caused by cell division. Congrats to @JamieEndicott, Paula Nolte, @shenhui1986 and @VAInstitute! nature.com/articles/s4146…
Interview of one of my mentors and long-time collaborator, Dr. Steve Horvath, on #epigeneticclocks youtube.com/watch?v=b91_cl…
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YouTube
Longevity & Aging Series (S1, E3): Dr. Steve Horvath - Epigenetic...
An absolute public health hero...many times over.
"...our best mortality risk predictor...DNA Methylation GrimAge...it strongly predicts healthspan and lifespan. It makes a strong claim but, I can assure you, this has been replicated in (20) other papers."
Very excited to be a part of this collaboration with @AgingJrnl and the ability to sit down with Steve Horvath! Listen in to hear Horvath discuss past aging studies. Hosted by our very own @drbrianchen youtu.be/6aQNeU6_1C8 #aging #epigenetics #biologicalage
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YouTube
Longevity & Aging Series (S1, E2): Dr. Steve Horvath's Special...
Excited to dive into new research in aging with @AgingJrnl...straight from the authors themselves!
#PressRelease: @AgingJrnl and @foxo_tech are proud to present the #Longevity & #Aging Series. This new monthly video interview series invites Aging researchers to discuss their research with host @drbrianchen, Chief Science Officer at FOXO. Read more: aging-us.com/news_room/agin…
aging-us.com
Aging (Aging-US) and FOXO Present: The Longevity & Aging Series | Aging
Listen to an audio version of this press releaseBUFFALO, NY- June 22, 2022 – Aging (Aging-US) and FOXO Technologies have teamed up to present a special collaboration on aging research with a new...
Exciting to hear about new advances in #AI applied to drug discovery @InSilicoMeds
#LongevityandAging: Watch the first episode of the #Longevity & #Aging Series—featuring Aging authors Drs. Alex Zhavoronkov @biogerontology & Frank Pun on #PandaOmics, their AI-powered discovery engine. Full interview: youtube.com/watch?v=Td8tK5… @foxo_tech @drbrianchen #openaccess
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Longevity & Aging Series (S1, E1): Dr. Alex Zhavoronkov and Dr. Frank...
Horvath lab: Past and Present (minus a few others). What an honor to spend a week with these great minds! #grc2022
DNA methylation-based predictors of health: applications and statistical considerations go.nature.com/34RklTE #Review by @PaulYousefi, @mathsuderman, @RyanLangdon19, Oliver Whitehurst, @mendel_random & @carolinerelton @MRC_IEU @BrisCancerEpi @BrisPopHealth
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