Kevin Knopf
@drkevinknopf
Hematologist/Oncologist. Health Services researcher / Health Tech / Cost-effectiveness. Whisky drinker. All tweets my own.
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Published on a really interesting topic - Fragmentomics We could determine chemotherapy efficacy by Day 20 - before any scans or other approaches. Hopeful this approach sees traction in the clinic My research is available on @ResearchGate: researchgate.net/publication/39…
Physicists Take the Imaginary Numbers Out of Quantum Mechanics quantamagazine.org/physicists-tak… via @QuantaMagazine
How do oncology providers around the 🌏 think about value in cancer care? 🤔Checkout this analysis in @JCOGO_ASCO @AHNtoday ascopubs.org/doi/10.1200/GO…
The next video in the Laplace Transform sequence is up! youtu.be/FE-hM1kRK4Y Here, we dig into a concrete example, the forced oscillator. Some of you may remember that this was relevant for studying why light slows down in a medium.
Looking for Best of ESMO #GU edition? We got you covered. @oncology_bg does a critical appraisal of the following #GU trials that made news at #ESMO25. ecancer.org/en/video/12543… Keynote 905 #ALBAN and #POTOMAC #PSAMAddition #EMBARK DV plus Toripalimab #IMVigor011
How to develop good research questions nature.com/articles/s4156… #MedEd #MedX #Science #phdlife #PHD #AcademicTwitter #academicWriting
Happy Friday! Looking to catch up on major highlights from #ESMO25 over the weekend? We got you covered! Watch this 30 min video for your Best of ESMO! ecancer.org/en/video/12543…
Friday afternoon- at 4:30 - staff gone so I’m just sitting here charting in EPIC and listening to a Springsteen concert from 1975 (Live at the Main Point)
Forgive the bad screen shot as I have bad wifi - but whoa! New NCCN option for TP53 aberrant CLL, MRD guided Z+V as per SEQUOIA arm D study. I would prefer this over A+V in this population who was excluded from AMPLIFY trial. AVO still reasonable though a la DFCI study. #cllsm
PAULIEN Open-label, phase Ill, randomized trial 🥊 Pembrolizumab + chemotherapy vs pembro alone in PD-L1 ≥50% NSCLC Halted due to futility. No differences seen on PFS or OS. More toxic with chemo. Food for thought now we are starting to have prospective data to this relevant…
#ESMO25 surprise: PRODIGE 81: ATEZO + BEV ± IPI (1 mg/kg) n=226 pts ➡️Adding IPI showed no benefit, ORR (30% vs 27.4%) Confusing b/c IPI at 1mg/kg is active in HCC (ORR for NIVO/IPI 1 is ~2x NIVO mono) & NIVO/IPI is active post ATEZO + BEV --> Doublets here to stay a while☹️
We authored / edited a special issue of DeVita on Cancer Drug Shortages - a problem that doesn't seem to be going away : journals.lww.com/journalppo/pag…
Is this real life?
Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com
This guy is in charge of US health care.
Inside the hospital ‘war rooms’ bracing for Medicaid cuts statnews.com/2025/09/15/hos… By @_daniel_payne.
On this day in 1975, Bob Dylan appeared on The World of John Hammond. It was filmed at WTTW in Chicago for later broadcast on PBS. Joined by violinist Scarlet Rivera, bassist Rob Stoner, and drummer Howie Wyeth, they performed Hurricane, Oh Sister, and Simple Twist of Fate.
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