I am thrilled to announce I'll be joining @StJude Children's Research Hospital as a Postdoctoral Research Fellow at @TheBlanchardLab. Looking forward to being part of an exceptionally talented research group and immerse myself in working with #smFRET and #CryoEM methods #postdoc
Here is a nice post in @NaturePortfolio summarizing our recent findings on the chemotherapeutic CX-5461, written with @MinPAN47830227, @jakebatch11 and @TheBlanchardLab. cancercommunity.nature.com/posts/the-chem…
New paper out from our lab investigating the use of the putative RNA-POL I inhibitor CX-5461 in pediatric neuroblastoma. I believe this study represents a fantastic example of why the details of drug mechanism are deeply important for patient safety. nature.com/articles/s4146…
nature.com
The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk...
Nature Communications - CX-5461 recently progressed through phase I clinical trial as a first-inhuman inhibitor of RNA-POL I. Here, the authors demonstrate that CX-5461 synergizes with...
Tuning the Baird aromatic triplet-state energy of cyclooctatetraene to maximize the self-healing mechanism in organic fluorophores pnas.org/content/early/…
So proud to be a part of this outstanding collaborative effort to explore the unexpected discovery and physiological significance of an EMT-associated ribosome biogenesis program: disq.us/t/3ehf3jj
Our previous paper showed that variant rRNA alleles are conserved and exhibit tissue-specific expression (Parks et al. Sci Adv). We now show that a conserved rRNA allele in E. coli is upregulated under stress and can regulate gene expression and phenotype. cell.com/cell-reports/f…
In a new @ScienceAdvances study, @TheBlanchardLab and team found that each person contains a wide variety of #ribosomes. Study suggests that genetic variation of rDNA may affect the way proteins are built, linking to developmental disorders. bit.ly/2oJo51k
A paper just published in Science Advances, "Variant ribosomal RNA alleles are conserved and exhibit tissue-specific expression," reveals that the sequences of ribosomal RNA within the mammalian ribosome may be significantly more divergent than expected: advances.sciencemag.org/content/4/2/ea…
Crick and Reynolds is the take for pirates in mccutchen deal. @extrabaggs @PavlovicNBCS on it. i only wish tony watson was still with the pirates so he could have combined to form a crick and watson combo in their pen (nerd joke)
@dodgerhat this is a great tweet. Why didn’t you like it???
When you start a business but you have a life also
Madison Bumgarner's first pitch is a called strike, and all is right with the world. OK. Maybe not.
Mets fans waking up, finding out they've signed Tim Tebow... 😱😭
"Nothing was funny for Seneca." atmilb.com/ZQgJK7
Four years ago today, home plate umpire Mario Seneca ejected Daytona Cubs ORGANIST Derek Dye after he played Three Blind Mice. @MiLB
#Marlins Giancarlo Stanton Last 215 plate appearances: 11 HR #SFGiants Madison Bumgarner Last 215 plate appearances: 11 HR
33 (993): @Twins select Davidson Col RHP Clark Beeker. m.mlb.com/draft/tracker#… #MLBDraft
MLB opening day. That special time of year when everyone unites to begin 7 straight months of rooting against the Yankees.
No matter how you feel about Trump politically, can you imagine him filling out a March madness bracket with @ESPNAndyKatz?
For all the Davidson lefty student athletes as well as our very own @GavinViano #lefty #southpaw #catsarewild
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