jsaez_phys's profile picture. Medical physicist tweeting about just anything...

Jordi Saez

@jsaez_phys

Medical physicist tweeting about just anything...

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1/ We previously (doi.org/10.1002/mp.149…) decribed the *trailing effect* caused by the stacking of two rounded-leaf end MLCs (aka, the Halcyon from @VarianMedSys). We have now identified clinical plans which exhibit the effect: doi.org/10.1002/mp.158…. Some details below:


Jordi Saez reposted

Here is a new and very interesting interview of Edward Witten, one of the greatest living theoretical physicists, by Brian Greene, discussing String theory, cosmology, nature of consciousness, etc. Highly recommended. Link: youtu.be/sAbP0magTVY?si…

Saman_Habibi_E's tweet image. Here is a new and very interesting interview of Edward Witten, one of the greatest living theoretical physicists, by Brian Greene, discussing String theory, cosmology, nature of consciousness, etc. Highly recommended. Link: youtu.be/sAbP0magTVY?si…

Jordi Saez reposted

Bombshell: Oliver Sacks (a humane man & a fine essayist) made up many of the details in his famous case studies, deluding neuroscientists, psychologists, & general readers for decades. The man who mistook his wife for a hat? The autistic twins who generated multi-digit prime…


Jordi Saez reposted

When the Japanese decide to master something, whether it’s cars, cameras, animation, knives, or yes, whiskey and craft cheese - they will perfect it into its final Platonic form. How do they do it? Obsession with kaizen (continuous improvement). And they will apply themselves…

MsMelChen's tweet image. When the Japanese decide to master something, whether it’s cars, cameras, animation, knives, or yes, whiskey and craft cheese - they will perfect it into its final Platonic form. 

How do they do it? 

Obsession with kaizen (continuous improvement). And they will apply themselves…

No culture is safe from nerds in Japan. Any song your people have or dish they make. Japanese autism will seize it and do it ten times better than your ancestors could’ve ever imagined.



Jordi Saez reposted

Whoever hasn't seen this documentary is missing out on what was possibly the greatest mathematical event of the 20th century...

Andrew Wiles on the morning he discovered how to fix his proof of Fermat's Last Theorem



Jordi Saez reposted

‼️ I love 🇮🇹 and recognize the effort here, but ORR 17.5% v 10% and mPFS 3.5 months v 2.8 months are a very nice example of statistical significance & clinical insignificance +21 days mPFS here = Precision Oncology is marketing more than anything else. Can we finally admit it?

🇮🇹 The ROME trial marks a milestone for Italy’s precision oncology platform: 6 years of dedication, 40 centers, 1,794 patients sequenced. A national effort to bring genomics to the heart of cancer care. @myESMO @IEOufficiale @LaStatale

curijoey's tweet image. 🇮🇹 The ROME trial marks a milestone for Italy’s precision oncology platform: 6 years of dedication, 40 centers, 1,794 patients sequenced. A national effort to bring genomics to the heart of cancer care. @myESMO @IEOufficiale @LaStatale


Jordi Saez reposted

Protons are worse for prostates, worse for H&N recurrence, side effects, higher cost, much less accessible Payors need to stop paying for this


Jordi Saez reposted

A new study has found that phone-free students performed better academically. But its findings will not end the argument over phones in schools economist.com/united-states/…


Jordi Saez reposted

They never should have drawn any conclusions about the lung V5 based upon a tiny retrospective analysis of 13 patients that did not even show statistical significance correlating the V5 with anything.


Jordi Saez reposted

Our Delphi consensus-based approach included 83 thoracic radiation oncologists in at least one survey to create consensus-based OAR dose constraint and target goal templates for lung cancer radiation therapy. What do you think? What comes next? Link here: practicalradonc.org/article/S1879-…

subatomicdoc's tweet image. Our Delphi consensus-based approach included 83 thoracic radiation oncologists in at least one survey to create consensus-based OAR dose constraint and target goal templates for lung cancer radiation therapy.

What do you think? What comes next?
Link here:
practicalradonc.org/article/S1879-……

Jordi Saez reposted

Our very own @PattyDiezH was awarded honorary membership of @RCRadiologists for her contribution to #RTQA and #clinicaltrials over the last 2 decades. Congratulations!!! #radonc #medphys

RTTQA_UK's tweet image. Our very own @PattyDiezH was awarded honorary membership of @RCRadiologists for her contribution to #RTQA and #clinicaltrials over the last 2 decades. Congratulations!!! #radonc #medphys
RTTQA_UK's tweet image. Our very own @PattyDiezH was awarded honorary membership of @RCRadiologists for her contribution to #RTQA and #clinicaltrials over the last 2 decades. Congratulations!!! #radonc #medphys
RTTQA_UK's tweet image. Our very own @PattyDiezH was awarded honorary membership of @RCRadiologists for her contribution to #RTQA and #clinicaltrials over the last 2 decades. Congratulations!!! #radonc #medphys

Jordi Saez reposted

New in the #RedJournal: Is the IROC H&N credentialing phantom an effective surrogate for different anatomical sites? @freettabrooks, @MalloryCGlenn, @JulieLarkin305, @DrRebeccaHowel1, @CatharineHClark, @MDAndersonNews tinyurl.com/brooksrj

ASTRO_org's tweet image. New in the #RedJournal: Is the IROC H&N credentialing phantom an effective surrogate for different anatomical sites? @freettabrooks, @MalloryCGlenn, @JulieLarkin305, @DrRebeccaHowel1, @CatharineHClark, @MDAndersonNews tinyurl.com/brooksrj

Jordi Saez reposted

Doing good science is 90% finding a science buddy to constantly talk to about the project.

ItaiYanai's tweet image. Doing good science is 90% finding a science buddy to constantly talk to about the project.

Jordi Saez reposted

👏🏽Take a bow 🙇🏼 @drjefstathiou Very clear results - no superiority of protons over photons for prostate cancer. Interesting - no benefit of spacer. We asked the Q, you gave us the answer! No protons for #prostatecancer Not cost-effective #ASTRO24 @ASTRO_org @IJROBP @ESTRO_RT

achoud72's tweet image. 👏🏽Take a bow 🙇🏼 @drjefstathiou Very clear results - no superiority of protons over photons for prostate cancer. Interesting - no benefit of spacer. We asked the Q, you gave us the answer! No protons for #prostatecancer Not cost-effective #ASTRO24 @ASTRO_org @IJROBP @ESTRO_RT
achoud72's tweet image. 👏🏽Take a bow 🙇🏼 @drjefstathiou Very clear results - no superiority of protons over photons for prostate cancer. Interesting - no benefit of spacer. We asked the Q, you gave us the answer! No protons for #prostatecancer Not cost-effective #ASTRO24 @ASTRO_org @IJROBP @ESTRO_RT
achoud72's tweet image. 👏🏽Take a bow 🙇🏼 @drjefstathiou Very clear results - no superiority of protons over photons for prostate cancer. Interesting - no benefit of spacer. We asked the Q, you gave us the answer! No protons for #prostatecancer Not cost-effective #ASTRO24 @ASTRO_org @IJROBP @ESTRO_RT
achoud72's tweet image. 👏🏽Take a bow 🙇🏼 @drjefstathiou Very clear results - no superiority of protons over photons for prostate cancer. Interesting - no benefit of spacer. We asked the Q, you gave us the answer! No protons for #prostatecancer Not cost-effective #ASTRO24 @ASTRO_org @IJROBP @ESTRO_RT

Jordi Saez reposted

There's one thing of which we can be confident, there is no number of negative proton trials for PCa that will dampen the enthusiasm of proton centers to aggressively market to patients.


Jordi Saez reposted

49 - Risk of Radiation Myelitis after Hypofractionated Spine SBRT Amazing work, @Chris_JacksonMD! Any insight on 0.35-1.2cc? This data looks ideal to explore whether 18 Gy to 0.35 cc or 12.3-13 Gy to 1.2 cc (TG-101) are meaningful! @JAMRadOnc @NicholasZaorsky #ASTRO24 #radonc

jryckman3's tweet image. 49 - Risk of Radiation Myelitis after Hypofractionated Spine SBRT

Amazing work, @Chris_JacksonMD! 

Any insight on 0.35-1.2cc? This data looks ideal to explore whether 18 Gy to 0.35 cc or 12.3-13 Gy to 1.2 cc (TG-101) are meaningful! @JAMRadOnc @NicholasZaorsky #ASTRO24 #radonc

Jordi Saez reposted

15 fx protons for PMRT is also a dud 50/25, RBE 1.1 vs 40.05/15 RBE 1.1 proton PMRT Primary endpoint: 2-year complication rate, non-inferiority, 10% NI margin Results: one-sided 95% CI 18.5 👎 Why use protons at all in this setting? I don’t get it 🤷‍♂️ #ASTRO24

5_utr's tweet image. 15 fx protons for PMRT is also a dud

50/25, RBE 1.1 vs 40.05/15 RBE 1.1 proton PMRT

Primary endpoint: 2-year complication rate, non-inferiority, 10% NI margin 

Results: one-sided 95% CI 18.5 👎 

Why use protons at all in this setting? I don’t get it 🤷‍♂️ #ASTRO24

Jordi Saez reposted

🚨 “HenRIetta” Phase 2 Breast and RNI w/ 42.56 Gy in 16 daily fractions Primary endpoint: rate of lymphedema at 3 years Hypofrac was NOT non-inferior (7% NI margin) for lymphedema!! #ASTRO24 Authors conclusions: spin

5_utr's tweet image. 🚨 “HenRIetta”
Phase 2
Breast and RNI w/ 42.56 Gy in 16 daily fractions

Primary endpoint: rate of lymphedema at 3 years

Hypofrac was NOT non-inferior (7% NI margin) for lymphedema!! #ASTRO24 

Authors conclusions: spin

Jordi Saez reposted

ASTRO abstracts are no longer embargoed after 5PM EST 9/27. Here is LBA1: PARTIQoL, Phase III study of protons vs IMRT for LR/IR prostate cancer. No significant differences in tumor control or patient-reported quality of life out to 60 months of follow up. #radonc

yuanjamesrao's tweet image. ASTRO abstracts are no longer embargoed after 5PM EST 9/27.  Here is LBA1:  PARTIQoL, Phase III study of protons vs IMRT for LR/IR prostate cancer. No significant differences in tumor control or patient-reported quality of life out to 60 months of follow up. #radonc

Jordi Saez reposted

On this day 30 years ago, Andrew Wiles, stunned the mathematical world by presenting his proof of Fermat's Last Theorem.

fermatslibrary's tweet image. On this day 30 years ago, Andrew Wiles, stunned the mathematical world by presenting his proof of Fermat's Last Theorem.

Jordi Saez reposted

Lucky to have seen first hand the tremendous work of this #radonc team. Thank you @MeritxellMolla for taking the time to show us your busy facility and share ideas. I’m still so jealous of your busy orthovoltage skin cancer service, your patients are very fortunate!

Fa 1 any varem inagurar el centre d’Oncologia Radioterapica @hospitalclinic Seu Granollers 750 primeres visites✅ 2150 seguiments✅ 690 tractaments✅ Objectiu: garantir un tractament integral centrat en el pacient. Gracies a tots els professionals q ho fan possible#OncoRadClinic

MeritxellMolla's tweet image. Fa 1 any varem inagurar el centre d’Oncologia Radioterapica @hospitalclinic Seu Granollers
750 primeres visites✅
2150 seguiments✅
690 tractaments✅
Objectiu: garantir un tractament integral centrat en el pacient.
Gracies a tots els professionals q ho fan possible#OncoRadClinic
MeritxellMolla's tweet image. Fa 1 any varem inagurar el centre d’Oncologia Radioterapica @hospitalclinic Seu Granollers
750 primeres visites✅
2150 seguiments✅
690 tractaments✅
Objectiu: garantir un tractament integral centrat en el pacient.
Gracies a tots els professionals q ho fan possible#OncoRadClinic


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