Shawn Lupold
@lupold_lab
Studying urologic cancers, especially #prostatecancer, to develop diagnostic, prognostic & therapeutic tools. #microRNA #aptamers #noncodingRNA
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Good morning #SBUR2025! Beautiful in Orlando. Looking forward to today’s sessions!
Pleased to see the official release of our research letter in @jclinicalinvest. We leveraged a publicly available scRNA-seq dataset and asked how prostate cancer cells systemically reprogram the cells of the bone marrow. jci.org/articles/view/…
Finally out today in nature.com/articles/s4158… 3D chromatin reorganization in prostate cancer lineage transformation, critically regulated by Nkx2-1 transcriptional network.
We’re pleased to share our new study: Among the first glimpses of miRNA activity at single-cell resolution in situ in a solid tumor. miR-21 loss slows MYC-driven prostate cancer and disrupts the immunosuppressive TME. 📖 biorxiv.org/content/10.110… #miRNA #ProstateCancer #scRNAseq
Congratulations David McConkey on the Donald S Coffey Lectureship. A true tour de force on translational bladder cancer research. #AUA2025 #AUA25 #SBUR.
Congratulations to all the 2024 SBUR Fall Meeting Travel Award Winners! Over the coming weeks, we'll be featuring each awardee's exciting research. Stay tuned!
Polyaneuploid cancer cells drive metastasis and resist treatments in #ProstateCancer. @sr_amend @HopkinsMedicine joins @AndreaMiyahira @PCFnews to discuss her research on polyaneuploid cancer cells (PACCs) and their role in metastasis, published in @MCR_AACR. #WatchNow on…
Check out our latest study! Comparative transcriptomics reveals a mixed basal, club, and hillock epithelial cell identity in castration-resistant prostate cancer | PNAS pnas.org/doi/10.1073/pn…
Slashing NIH indirect costs to 15% will devastate U.S. research, innovation, and biotech leadership; crippling drug development, diagnostics, clinical trials, and scientific training. This will impact our global edge in medicine and have an economic impact far beyond universities
Excited to share a new paper by postdoc Dr. Kiel Tietz @UMNCancer! CPSF1 inhibition promotes widespread use of intergenic polyadenylation sites and impairs glycolysis in prostate cancer cells: Cell Reports cell.com/cell-reports/f… Work funded by @CDMRP and @NCICancerBio
THRILLED to announce @LotanLab 5th Director of Research @brady_urology in footsteps of Don Coffey to transform care & mentor leaders! 1st woman to hold position. Dr. Pienta to serve as Special Advisor to Provost & advance to Director Innovation and Strategy! CONGRATULATIONS!
Excited about our new paper! Incredibly innovative conceptual development from brilliant former post-doc @augelloma, with incredibly talented post-doc Xuanrong Chen moving it forward and getting it over the finish line 1/N nature.com/articles/s4146…
Congratulations Isaacson Bababode Adelani on being a 2024 DuBose Postdoctoral Fellow Runner-Up Finalists. @brady_urology @zikson_b jhmlink.org/member/Post/20…
Hopkins is recruiting 30 Bloomberg Distinguished Professors in AI + X (X = astrophysics, cancer, neuroscience, genomics, social sciences, etc.) hub.jhu.edu/2024/12/17/dat… 22 of these 30 will be organized in clusters:
Our paper out today in @NatureComms analyzed plasma from the phase 3 @ALLIANCE_org A031201 trial using the AR-ctDETECT assay. Patients positive for circulating tumor DNA had poor overall survival despite treatment with potent AR inhibitors. rdcu.be/d28wf
Please share - Cancer Research summer internship opportunity for HBCU students here at @hopkinskimmel - deadline January 13th!
Nate Brennan reporting on LSD1 as a target for suppressing the neuroendocrine phenotype of prostate cancer #SBUR2025
Russell Szmulewitz gives a great update on the clinical management of metastatic prostate cancer. #SBUR2024
@sr_amend from @brady_urology Endocyling cells are a convergent phenotype of therapy resistance #SBUR2024
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