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End of a great chapter as I step down as CTO at @CellinoBio. 8+ years ago we started on a novel idea from @nabsicle and @MadridMarinna and my home-grown prototype here. With the venture solidly in commercialization mode, it’s time for the next exciting challenge…
Best feed— and as an optics/imaging fanatic this one in particular hits a nerve!
One of my favorite technologies, developed in recent years, is two-photon holographic optogenetics. It is a way to both stimulate and record activity from thousands of individual neurons in real-time; akin to playing the brain like a piano. Here is how it works: In classical…
It brings me great joy to read the poetry of Arthur Sze, our new US Poet Laureate, who went to my high school then MIT and then struck his own path. poetryfoundation.org/poems/152053/f…
Big bets on technology have changed many industries. But where is that same boldness in pharma? Our industry is trapped by conventional thinking and incrementalism. Delivering breakthroughs requires systems-level changes – and a willingness to embrace ambitious ideas and the…
Cool closed-loop optical control of biology!
🔬🧠 Our paper on smart microscopy & the issue of interoperability! biorxiv.org/content/10.110… LONG THREAD WARNING: Smart microscopy uses real-time image analysis to automatically guide the acquisition or perturbation (closed feedback-control loop). Many applications exist:
A shout-out to the @TSA: was traveling through @DTWeetin from Tokyo last week when I got distracted by them inspecting my bottle of Nikka and left my fleece+pods. FedEx'ed back to me in days! Thank you.
📢 You’re invited! Hear Dr. Hideyuki Okano, President of @ISSCR and Professor at @Keio_Univ, share results from the world’s first #clinicaltrial using #iPSC-derived neural stem cells to treat #spinalcordinjury—where one previously paralyzed patient has even regained the ability…
Capturing that feeling that basic science has slowed to a crawl. Recent moves not going to help.
Research Suggests Life On Earth Began Full 20 Minutes Earlier Than Previously Thought theonion.com/research-sugge…
this Continuous Thought Machine post is so cool
Incredible work by our team!
🚀 Exciting news! Cellino’s iPSC manufacturing technology has received the @US_FDA Advanced Manufacturing Technology (AMT) designation, recognizing the potential to enhance scalability & quality in personalized #regenmed! Learn more: businesswire.com/news/home/2025…
Founders, armed with superpowers in software and AI, are incredibly excited to solve important problems in the physical world, and build big companies. Some startups I met just in the last few days: - data generation/models for robotics - Construction software - AI for…
Stem cell therapy for Parkinson’s disease has entered a new era. Two @Nature studies demonstrate that pluripotent stem cell–derived dopamine neurons can survive, restore function, and potentially change the treatment paradigm for this neurodegenerative disease.
Our latest paper, "Phase retrieval via Zernike phase contrast microscopy with an untrained neural network," is now published! Turn your commercial phase-contrast microscope into a quantitative phase microscope—without any hardware modification. opg.optica.org/oe/fulltext.cf…
Ari (@AriWagen) made an interface for IR spectral predictions that's so easy to use that it's hypnotizing. I measured and computed dozens of IR spectra in my PhD, perhaps hundreds, and this is the most intuitive way to interact with the data that I've ever encountered:
People make fun of Americans for always “doing great.” But that reflexive optimism is a core part of the American psyche…and maybe its secret power
This is really cool!
On Tuesday, Governor Healey was joined by @MassEOED Secretary Yvonne Hao, MLSC President and CEO Kirk Taylor, and leaders from @MassGenBrigham for a visit to @CellinoBio . The company is partnering with Mass General Brigham to build the world’s first autonomous iPSC foundry.
What a day! 🎉 We celebrated our collaboration with @MassGenBrigham with an incredible community of supporters, including the inspiring @MassGovernor & Sec. Yvonne Hao. Grateful to @MassGenBrigham as we build the world’s first autologous iPSC foundry together! #biotech…
Great research on open-source by @Harvard: - $4.15B invested in open-source generates $8.8T of value for companies (aka $1 invested in open-source = $2,000 of value created) - Companies would need to spend 3.5 times more on software than they currently do if OSS did not exist I…
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