Mike_Mqt
@mult1fractal
Nanopore sequencing, targeted sequencing (adaptive sampling), Flowcell slayer, PhD Student, Bioinformatics
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🚨 Preprint! We've adapted SC2 wastewater surv to track the 2022 #mpox outbreak in Germany using a novel NGS panel 🧪 ✅ 90% MPXV genome coverage 🧬 Specific mutations 📍 Wastewater = stigma-free surveillance Led by - @Lackner_TUDa, check it out: 🔗 shorturl.at/aMv97
Thrilled to share our new publication 🎉 🥳 We demonstrate that metabolic-based probes (CAM/TMA-DPH) outperform membrane integrity assays (SYTO9/PI) in precision and consistency for biofilm viability assessment across diverse bacterial species.
New Research: CAM/TMA-DPH as a promising alternative to SYTO9/PI for cell viability assessment in bacterial biofilms frontiersin.org/articles/10.33… #FrontiersIn #CellularInfectionMicrobiology
🎉 📢Excited to announce my paper, "PEG-PLGA nanoparticles deposited in Pseudomonas aeruginosa and Burkholderia cenocepacia", is published! doi.org/10.1016/j.jpha… This study is highlighting PEG-PLGA's potential for effective drug delivery in Gram-negative bacteria.
Happy to be part of #TargetingPhageTherapy2024 conference in beautiful Malta and meeting new people from #phagecommunity and my former colleagues from #Eliavainsitute
Bacteriophage-mediated decolonization of Klebsiella pneumoniae in a novel Galleria mellonella gut colonization model with Enterobacteriaceae dlvr.it/T1G2yV
great colab with @martinhoelzer @gcloudChris @mult1fractal -- thx guys!
We are pleased to announce a new protocol explaining how to recover a DNA library mid-sequencing run. This protocol has been developed to enable precious samples to be recovered and transferred to a new flow cell for continued sequencing. Learn more: bit.ly/3QwCTfi
What the #Phage: an easy-to-use and parallel multitool approach for phage prediction combined with an #annotation and #classification downstream strategy. [co-authored by EVBC members @mult1fractal @martinhoelzer @DrPletz @phiweger R. Ehricht] doi.org/10.1093/gigasc…
Mitarbeiter für Wissenschaftskommunikation (w/m/d) gesucht infectognostics.de/jobs
"What the Phage?" In diesem Artikel wird ein skalierbarer Arbeitsablauf für die Identifizierung und Analyse von #Phagen sequenzen vorgestellt @UKJ_Jena @nanozoo academic.oup.com/gigascience/ar…
People asked for documentation, so "faltwerk" -- a python library to explore protein structures spatially -- now lives on readthedocs, and v0.5 has even better support for protein complexes -- github.com/phiweger/faltw…
github.com
GitHub - phiweger/faltwerk: A library for spatial exploratory data analysis of protein structures
A library for spatial exploratory data analysis of protein structures - phiweger/faltwerk
Our case report highlights how rapid @nanopore sequencing helps us out in our Hospital @UKJ_Jena when encountering inconclusive VITEK results. We only needed 7.5 h from the isolate to sequence results using standard kits and sequencing protocols. fortuneonline.org/articles/a-rar…
Our latest work led by @mikemc423 on bioRxiv goes deep on "Implications of taxonomic bias for microbial differential-abundance analysis": biorxiv.org/content/10.110… Metagenomic sequencing is biased. When are differential abundance (DA) results still valid? #NCStateMicrobiome 1/
VIRify: an integrated detection, annotation and taxonomic classification pipeline using virus-specific protein profile hidden Markov ... biorxiv.org/cgi/content/sh… #biorxiv_bioinfo
I went down this rabbit hole of _spatial_ analysis of protein structures, now easily generated using eg #alphafold. Interestingly, there were many annoying steps that got in the way, and I also wanted something workflow-compatible. Therefore: github.com/phiweger/faltw…
github.com
GitHub - phiweger/faltwerk: A library for spatial exploratory data analysis of protein structures
A library for spatial exploratory data analysis of protein structures - phiweger/faltwerk
Identification of bacteriophage genome sequences with representation learning dlvr.it/SWl5vy
@nanopore's fastq file header contain the basecalling model info. Anyone has a parser/tool to figure out which medaka model to use based on that info?
Our new Kit V14 chemistry, for Q20+ raw read accuracy, is now available to purchase from the store as part of an open early access program. Kit V14 allows users to tune experiments for high-accuracy, high-yield #nanopore sequencing as required. Learn more: bit.ly/3udvvf3
DER PLAN DER HOCHSCHULREKTOREN Nächste Woche will die #HRK ihren Vorschlag für die Reform des #Wissenschaftszeitvertragsgesetz/es beschließen. Was wird drinstehen? Interview mit Anja Steinbeck und Peter-André Alt. #IchBinHanna @HRK_aktuell jmwiarda.de/2022/06/27/der…
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