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Excited to share our latest publication in @SciImmunology! We've uncovered an NK cell-mediated immune checkpoint (B7H6 : NKp30) that limits CAR T cell persistence, revealing new insights into immune regulation. #Immunology @broadinstitute @DKFZ science.org/doi/10.1126/sc…
After four years, 350 included patients and over 300 participating students we @sigmastudies can proudly announce the publications of #EXPELLIARMUS - the first student-led multicentre randomised controlled trial. Huge thanks to everyone involved! journals.lww.com/annalsofsurger…
Super happy to share that our work is out now in @NatureComms. A huge thank you to my amazing co-first authors @FARadtke and Tarik Exner, to @grieshaber for your guidance, and to everyone else involved! nature.com/articles/s4146…
Sad to miss #ASHG2023 but I will advertise a talk by @n_hackert and a poster by @Dany_geny.
The future of biotech is global. Announcing eight new chapters around the world. nucleatehq.medium.com/biotech-is-glo…
The Chapter I of my postdoc journey at @kuchroolab is now online! Beyond our findings, it's been an incredible human experience. We describe a B-cell state expressing checkpoint molecules uncovering Tim-1, as a potent regulator of anti-tumor immunity: nature.com/articles/s4158…. 1/5
My first cover story in this month's issue of @Cancer_Cell! 🍾 "On the cover: Friedrich et al. (711–725) reveal the mode of action of bispecific antibodies in patients with multiple myeloma." Check it out: cell.com/cancer-cell/cu… cell.com/cancer-cell/fu…
I‘m very grateful for getting the opportunity to present my research at HVS 2023 and receiving the best basic science poster award. This wouldn’t be possible without support of @caseylclift , @FloSicklinger , @avankampenMD , @floleuleu, @AikawaElena and many more. @CICSnews
Next one out (and first paper with Feng Zhang @ Broad Institute of MIT and Harvard): Spearheaded by the amazing grad student Joe Kreitz, we developed a complete new system for future in vivo gene therapy delivery: Check it out! ⬇ nature.com/articles/s4158…
I’m very excited to share our latest work on mapping eQTLs for classical HLA genes at single-cell resolution across >1K individuals and 1.14 million cells: medrxiv.org/content/10.110… with @soumya_boston, @saorisakaue, @yluo86 @mariaGTAC, and many other awesome folks.✨ Tweetorial👇
Online Now: The pre-existing T cell landscape determines the response to bispecific T cell engagers in multiple myeloma patients dlvr.it/Skdjld
Really looking forward to my visit and talk @WWU_Muenster this week! An entire SFB devoted to neutrophils 🤯 What a fantastic idea! medizin.uni-muenster.de/sfb-trr-332/ev… @CRC_TRR332 @soehnleinlab @Carlos_Silvestr
Very happy to share that our work on the transcriptional conservation between human and murine neutrophil cell states is out on #bioRxiv. @grieshaber @FARadtke
New preprint from our lab! Kudos to first authors @n_hackert and @radtke_f We tackled two questions: 1. What is the degree of transcriptional conservation in neutrophils between mice and humans? 2. Is there a shared backbone between divergent neutrophil states in inflammation?
We have exciting, funded, inter-institutional postdoc opportunities available in Heidelberg! Reach out if you are interested in working with @SinemKSaka1 at @embl and me on "Deciphering molecular heterogeneity of inflammatory rheumatic diseases with novel spatial omics methods"!
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