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@nonstandardcode

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What's great about this is that we can finally start putting numbers on the big questions in terraforming research. arxiv.org/abs/2510.07344

Mars could be green in our lifetime, but you’d still need an oxygen mask. With new capabilities in spaceflight & synthetic biology, current plans for Mars terraforming look very different from past visions. A thin, life-supporting atmosphere might be doable with modern tech.

Pioneer__Labs's tweet image. Mars could be green in our lifetime, but you’d still need an oxygen mask.

With new capabilities in spaceflight & synthetic biology, current plans for Mars terraforming look very different from past visions. A thin, life-supporting atmosphere might be doable with modern tech.


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Simultaneous in vitro expression of minimal 21 transfer RNAs by tRNA array method by Miyachi, R., Masuda, K., Shimizu, Y., Ichihashi, N. nature.com/articles/s4146…


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If you are an highschool student and you are conducting research in a lab, you are a scientist. If you are an undergraduate student and you are conducting research in a lab, you are a scientist.


Machine learning-guided evolution of pyrrolysyl-tRNA synthetase for improved incorporation efficiency of diverse noncanonical amino acids rdcu.be/ew4uf


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Michelle Chang of @PrincetonChem and colleagues publish in @NChemBio: “Terminal alkyne formation by a pyridoxal phosphate-dependent enzyme.” Great work! nature.com/articles/s4158…


From the chin lab Genetic Code-Locking Confers Stable Virus Resistance to a Recoded Organism | Biochemistry pubs.acs.org/doi/10.1021/ac…


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2 of 2: Instead of activating a water molecule for hydrolysis, as previously thought, release factors induce a structural change in the transfer RNA, enabling its own 2’OH group to attack and break the bond, a universal process in all organisms. science.org/doi/10.1126/sc…


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Online now! The continuous evolution of biomolecular force fields dlvr.it/TLNb6S


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Excited to share our newest paper, online today @Nature! We report the discovery of a highly unusual mechanism of antiviral immunity through the synthesis of long, homopolymeric DNA. nature.com/articles/s4158…

stephentang23's tweet image. Excited to share our newest paper, online today @Nature! We report the discovery of a highly unusual mechanism of antiviral immunity through the synthesis of long, homopolymeric DNA.

nature.com/articles/s4158…

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There is also a Colab notebook for EvoBindRare now! Try it and let us know what you think: colab.research.google.com/github/patrick…

RareFold predicts and designs proteins with noncanonical AAs. With EvoBindRare, we designed linear & cyclic peptide binders with high affinity & novel binding modes, validated in wet lab. A step toward next-gen therapeutics. 📄 biorxiv.org/content/10.110… 💻 github.com/patrickbryant1…

Patrick18287926's tweet image. RareFold predicts and designs proteins with noncanonical AAs. With EvoBindRare, we designed linear & cyclic peptide binders with high affinity & novel binding modes, validated in wet lab.
A step toward next-gen therapeutics.
📄 biorxiv.org/content/10.110…
💻 github.com/patrickbryant1…


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Happy to share the peer-reviewed and updated version of our work on OrthoRep-driven evolution of aaRSs for genetic code expansion with unnatural amino acids. Congrats to @yuichi_furuhata, a true master bioengineer, on leading this excellent work! nature.com/articles/s4146…


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Pushing the bounds of human capability across frontiers of intelligence, space & biotech is a mission I care deeply about. As federal science budgets enter a period of uncertainty - we're excited to step up with $100M for engineers & inventors affected by funding cuts.

1/ We're dedicating $100M to support American scientists facing funding cuts through the Lux Science Helpline, an expansion of our Lux Labs program. To compete in the future, innovation must be funded 🧪💡

Lux_Capital's tweet image. 1/ We're dedicating $100M to support American scientists facing funding cuts through the Lux Science Helpline, an expansion of our Lux Labs program. To compete in the future, innovation must be funded 🧪💡


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Escherichia coli with a 57-codon genetic code biorxiv.org/content/10.110… #biorxiv_synbio


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Seeing what bacteria see from a flying UAV 👁️ rdcu.be/ehkQB #synbio #biotech @itai_levin @yonchem

Geneticdesigner's tweet image. Seeing what bacteria see from a flying UAV 👁️
rdcu.be/ehkQB

#synbio #biotech @itai_levin @yonchem

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Designing Enzymatic Reactivity with an Expanded Palette "build new enzyme function through the incorporation of noncanonical amino acids and synthetic cofactors" …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cb…

paperperday's tweet image. Designing Enzymatic Reactivity with an Expanded Palette

"build new enzyme function through the incorporation of noncanonical amino acids and synthetic cofactors"

…mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cb…

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Chlamydomonas chloroplast genes tolerate compression of the genetic code to just 51 codons biorxiv.org/content/10.110… #biorxiv_synbio


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Hijacking a bacterial membrane transporter for efficient genetic code expansion biorxiv.org/content/10.110… #biorxiv_synbio


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Continuous in situ synthesis of a complete set of tRNAs sustains steady-state translation in a recombinant cell-free system. biorxiv.org/content/10.110… #biorxiv_synbio


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Thrilled (and relieved) to finally have this review by Arianna, Zeyi, and Kaitlyn out! Everything you've ever wanted to know about genetic code expansion in mammalian cells! pubs.acs.org/doi/10.1021/ac…


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