sclerodermaUM's profile picture. 👉University of Michigan Scleroderma Program leading the way through excellence in clinical care, teaching, & research #scleroderma tweets≠advice  Follow≠endorse

Dr. Dinesh Khanna

@sclerodermaUM

👉University of Michigan Scleroderma Program leading the way through excellence in clinical care, teaching, & research #scleroderma tweets≠advice Follow≠endorse

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We've received very touching #sclerodermastories from patients & family. Read them all at the link below. Please consider supporting the Michigan Medicine Scleroderma Program on #GivingBlueday 11/27/18, at medicine.umich.edu/dept/intmed/di…#medicineneedsvictors #victorsinthehouse #Rheum

sclerodermaUM's tweet image. We've received very touching #sclerodermastories from patients & family. Read them all at the link below. Please consider supporting the Michigan Medicine Scleroderma Program on #GivingBlueday 11/27/18, at medicine.umich.edu/dept/intmed/di… … #medicineneedsvictors #victorsinthehouse #Rheum

Dr. Dinesh Khanna reposted

🫁Better understand key characteristics and diverse subtypes of fibrosing #interstitiallungdisease with our NEW CE #Webinar Series! Register Now: ow.ly/WJSc50X5a8q @sclerodermaUM @DrBernstein #Rheumatology #rheumatologists #InterstitialLungDisease #LungDisease #CME

MLG_CME's tweet image. 🫁Better understand key characteristics and diverse subtypes of fibrosing #interstitiallungdisease with our NEW CE #Webinar Series!  Register Now: ow.ly/WJSc50X5a8q

@sclerodermaUM

@DrBernstein
#Rheumatology #rheumatologists #InterstitialLungDisease #LungDisease #CME

Interested in a career in scleroderma and related disorders? Join one of the largest programs with robust clinical research and trials. We are actively recruiting! @UMIntMed nejmcareercenter.org/job/920859/div… 📷


Interested in a position at U-M scleroderma program? Expertise in analyzing omics data. We are leading center in clinical trials and one of the largest scleroderma program. careers.umich.edu/job_detail/264…


Dr. Dinesh Khanna reposted

Join us today at 12 pm for Grand Rounds on "Systemic Sclerosis: An Update" presented by @sclerodermaUM, professor in the Division of Rheumatology. Learn more: medschool.umich.edu/departments/in…

UMIntMed's tweet image. Join us today at 12 pm for Grand Rounds on "Systemic Sclerosis: An Update" presented by @sclerodermaUM, professor in the Division of Rheumatology.

Learn more: medschool.umich.edu/departments/in…

Delighted to present @UMIntMed grand rounds today at noon ET. Systemic Sclerosis- an update! Join at umich.zoom.us/j/97732438261 Password:  606879

sclerodermaUM's tweet image. Delighted to present @UMIntMed grand rounds today at noon ET. Systemic Sclerosis- an update! Join at umich.zoom.us/j/97732438261
Password:  606879

Dr. Dinesh Khanna reposted

DID YOU KNOW? >30% of Systemic Sclerosis pts present without Raynauds!. Data from 2 large US cohorts, of SSc dx with puffy fingers/hands or other symptoms. Such patients presented with more severe skin and musculoskeletal disease. buff.ly/t6mFdB9

RheumNow's tweet image. DID YOU KNOW?  >30% of Systemic Sclerosis pts present without Raynauds!. Data from 2 large US cohorts,  of SSc dx with puffy fingers/hands or other symptoms. Such patients presented with more severe skin and musculoskeletal disease. buff.ly/t6mFdB9

Dr. Dinesh Khanna reposted

Bringing rheumatology closer to haematology. CAR-T therapy is showing tremendous promise in autoimmune conditions esp difficult to treat cases. #eular2025

Excited to present data from RESET-SSc in #scleroderma #eular2025. CAR-T was well tolerated with beneficial effects on skin/ FVC. Exciting data on U-M IIS with LN bx showing complete depletion of B cells at 3 weeks and NFC showing normalization of capillary density and size

sclerodermaUM's tweet image. Excited to present data from RESET-SSc in #scleroderma #eular2025. CAR-T was well tolerated with beneficial effects on skin/ FVC. Exciting data on U-M IIS with LN bx showing complete depletion of B cells at 3 weeks and NFC showing normalization of capillary density and size
sclerodermaUM's tweet image. Excited to present data from RESET-SSc in #scleroderma #eular2025. CAR-T was well tolerated with beneficial effects on skin/ FVC. Exciting data on U-M IIS with LN bx showing complete depletion of B cells at 3 weeks and NFC showing normalization of capillary density and size
sclerodermaUM's tweet image. Excited to present data from RESET-SSc in #scleroderma #eular2025. CAR-T was well tolerated with beneficial effects on skin/ FVC. Exciting data on U-M IIS with LN bx showing complete depletion of B cells at 3 weeks and NFC showing normalization of capillary density and size
sclerodermaUM's tweet image. Excited to present data from RESET-SSc in #scleroderma #eular2025. CAR-T was well tolerated with beneficial effects on skin/ FVC. Exciting data on U-M IIS with LN bx showing complete depletion of B cells at 3 weeks and NFC showing normalization of capillary density and size


“Normal” CPK by race and gender. ⁦@docrota⁩ ⁦@FloridaRheums

sclerodermaUM's tweet image. “Normal” CPK by race and gender. ⁦@docrota⁩   ⁦@FloridaRheums⁩

Great lecture by Dr Seo. Summary slide on ANCA vasculitis @floridarheums

sclerodermaUM's tweet image. Great lecture by Dr Seo. Summary slide on ANCA vasculitis @floridarheums

Dr. Dinesh Khanna reposted

Novel Rx for #scleroderma ?adaptive ?B cells ?Tcells ?anti inflammatory ?costimulatory ?interferon ⬇️ ?anti fibrotic ?vascular remodelling 🤔all of above Hope for #SSc @Worldsclerofnd @SclerodermaCAN @scleroderma_sso @SclerodermaNews @sclerodermaUM @FloridaRheums #FSR2025

Janetbirdope's tweet image. Novel Rx for #scleroderma

?adaptive
?B cells
?Tcells
?anti inflammatory 
?costimulatory
?interferon ⬇️
?anti fibrotic
?vascular remodelling 

🤔all of above 

Hope for #SSc @Worldsclerofnd @SclerodermaCAN @scleroderma_sso @SclerodermaNews

@sclerodermaUM @FloridaRheums #FSR2025
Janetbirdope's tweet image. Novel Rx for #scleroderma

?adaptive
?B cells
?Tcells
?anti inflammatory 
?costimulatory
?interferon ⬇️
?anti fibrotic
?vascular remodelling 

🤔all of above 

Hope for #SSc @Worldsclerofnd @SclerodermaCAN @scleroderma_sso @SclerodermaNews

@sclerodermaUM @FloridaRheums #FSR2025
Janetbirdope's tweet image. Novel Rx for #scleroderma

?adaptive
?B cells
?Tcells
?anti inflammatory 
?costimulatory
?interferon ⬇️
?anti fibrotic
?vascular remodelling 

🤔all of above 

Hope for #SSc @Worldsclerofnd @SclerodermaCAN @scleroderma_sso @SclerodermaNews

@sclerodermaUM @FloridaRheums #FSR2025

Dr. Dinesh Khanna reposted

#CAR-T in active #scleroderma #diffuse open label @sclerodermaUM presented improvement in #nailfold #capillary patterns Suggesting #vascular recovery Hope is for lungs, skin and survival to improve but These are ▶️ Early days ?risk OP0338 #EULAR2025. @RheumNow @eular_org

Janetbirdope's tweet image. #CAR-T in active #scleroderma #diffuse 

open label
@sclerodermaUM presented improvement in 
#nailfold #capillary patterns
Suggesting #vascular recovery

Hope is for lungs, skin and survival to improve but 
These are ▶️
Early days ?risk

OP0338
#EULAR2025. @RheumNow @eular_org

Dr. Dinesh Khanna reposted

🚨 Promising advances in #SystemicSclerosis at #EULAR2025! 🧬 CD19 CAR-T therapy shows encouraging efficacy in SLE, SSc & IIM with manageable safety ⚠️ 🔬 11+ ongoing Phase 2/3 trials in SSc(-ILD) targeting fibrosis, immunity, vasculopathy @sclerodermaUM

cristianasieiro's tweet image. 🚨 Promising advances in #SystemicSclerosis at #EULAR2025!
🧬 CD19 CAR-T therapy shows encouraging efficacy in SLE, SSc & IIM with manageable safety ⚠️
🔬 11+ ongoing Phase 2/3 trials in SSc(-ILD) targeting fibrosis, immunity, vasculopathy
@sclerodermaUM
cristianasieiro's tweet image. 🚨 Promising advances in #SystemicSclerosis at #EULAR2025!
🧬 CD19 CAR-T therapy shows encouraging efficacy in SLE, SSc & IIM with manageable safety ⚠️
🔬 11+ ongoing Phase 2/3 trials in SSc(-ILD) targeting fibrosis, immunity, vasculopathy
@sclerodermaUM
cristianasieiro's tweet image. 🚨 Promising advances in #SystemicSclerosis at #EULAR2025!
🧬 CD19 CAR-T therapy shows encouraging efficacy in SLE, SSc & IIM with manageable safety ⚠️
🔬 11+ ongoing Phase 2/3 trials in SSc(-ILD) targeting fibrosis, immunity, vasculopathy
@sclerodermaUM
cristianasieiro's tweet image. 🚨 Promising advances in #SystemicSclerosis at #EULAR2025!
🧬 CD19 CAR-T therapy shows encouraging efficacy in SLE, SSc & IIM with manageable safety ⚠️
🔬 11+ ongoing Phase 2/3 trials in SSc(-ILD) targeting fibrosis, immunity, vasculopathy
@sclerodermaUM

Considering Phase 3 trial in #scleroderma? if thinking about individual organ, consider this work presented at the #EULAR2025 and supported by SCTC and @NIH_NIAMS For composite endpoint, revised CRISS is being qualified by the regulatory agency

sclerodermaUM's tweet image. Considering Phase 3 trial in #scleroderma? if thinking about individual organ, consider this work presented at the #EULAR2025 and supported by SCTC and @NIH_NIAMS  For composite endpoint, revised CRISS is being qualified by the regulatory agency

Excited to present data from RESET-SSc in #scleroderma #eular2025. CAR-T was well tolerated with beneficial effects on skin/ FVC. Exciting data on U-M IIS with LN bx showing complete depletion of B cells at 3 weeks and NFC showing normalization of capillary density and size

sclerodermaUM's tweet image. Excited to present data from RESET-SSc in #scleroderma #eular2025. CAR-T was well tolerated with beneficial effects on skin/ FVC. Exciting data on U-M IIS with LN bx showing complete depletion of B cells at 3 weeks and NFC showing normalization of capillary density and size
sclerodermaUM's tweet image. Excited to present data from RESET-SSc in #scleroderma #eular2025. CAR-T was well tolerated with beneficial effects on skin/ FVC. Exciting data on U-M IIS with LN bx showing complete depletion of B cells at 3 weeks and NFC showing normalization of capillary density and size
sclerodermaUM's tweet image. Excited to present data from RESET-SSc in #scleroderma #eular2025. CAR-T was well tolerated with beneficial effects on skin/ FVC. Exciting data on U-M IIS with LN bx showing complete depletion of B cells at 3 weeks and NFC showing normalization of capillary density and size
sclerodermaUM's tweet image. Excited to present data from RESET-SSc in #scleroderma #eular2025. CAR-T was well tolerated with beneficial effects on skin/ FVC. Exciting data on U-M IIS with LN bx showing complete depletion of B cells at 3 weeks and NFC showing normalization of capillary density and size

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