Steven Lewis
@stevenmlewis7
aspiring physician-scientist @stonybrookmed MSTP | phd @caoresco lab @cshl | immunobio postgrad @stephanieeisen, undergrad @rmedzhitov | #LGM
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When we think about tumor suppressor genes and cancer risk, we think the 2 hit hypothesis and loss of heterozygosity - but what happens between hit 1 and 2? Check out our view on fascinating work from @Carman_MC_Li written w/my incredible advisor @caoresco nature.com/articles/s4158…
What a day for the Bulldogs 🔥 Yale's 45-28 win over Harvard claims the Bulldogs a share of the Ivy League regular season title and clinches the conference's FIRST-EVER automatic bid into the FCS playoffs 😤
i actually liked when you could spend 3-4 hours chilling at the ballpark instead of blinking and 5 innings are already gone
MLB games lasting 3+ hours: 2003: 28% 2004: 31% 2005: 30% 2006: 32% 2007: 39% 2008: 37% 2009: 38% 2010: 38% 2011: 40% 2012: 47% 2013: 52% 2014: 58% 2015: 46% 2016: 54% 2017: 62% 2018: 54% 2019: 62% 2020: 59% 2021: 67% 2022: 60% 2023: 17% ⏰ 2024: 12% ⏰ 2025: 15% ⏰
excited to share this work - we really do hope others in the MG field and those working w/other tissues (liver? Pancreas?!) will check this image analysis method out/find it useful - always a blast developing this w/the @caoresco crew! And a great collab w/the Navlakha lab @CSHL
Are you looking for a reliable strategy to analyze mammary tissue using whole mount images?? Well, maybe you should check MaGNet, our new computational based and user friendly approach (and you probably can adapt it to other organs as well). link.springer.com/article/10.100…
Check out our recent study showing how to re-activate estrogen responses in originally hormone low/negative breast cancer cells! Shoutout to the amazing @DeeptimanChatt2 @CicconeMichael @anandan_dhivyaa! nature.com/articles/s4146…
nature.com
Loss of BPTF restores estrogen response and suppresses metastasis of mammary tumors
Nature Communications - BPTF is known to regulate chromatin accessibility and self-renewal in mammary epithelial stem cells. Here, the authors discover that BPTF inhibition delays tumor formation,...
Early-onset cancers are on the rise—and scientists are racing to understand why. A new New York Times feature highlights research from CSHL Associate Professor Camila dos Santos on how pregnancy, breastfeeding, and even urinary tract infections can leave lasting marks on breast…
Did you know that breasts have branches? Disturbances to this tree of life can have implications for breast cancer risk. Now, three grad students in CSHL's @caoresco lab have developed a computer model for measuring such changes. #BreastCancerAwareness cshl.edu/the-magnetic-m…
John Oliver writers room rn
the John Oliver team currently debating how much prison time they want to serve for their next episode
The fact that the Mets didn’t send Taylor when they should have a few nights ago and they sent Marte when they shouldn’t have is just brutal.
Just found out Pete Crow Armstrong was on the Mets lol I’m sick😂😂
A Mets and Yankee fan kiss on the scoreboard as she shows off her engagement ring. The crowd boos.
Every single broadcast call of Jeff McNeil's game-winning HR in the 7th inning today. Includes Spanish calls & Yankees broadcasts.
The more I think about the more I realize 2024 was the year and we unfortunately blew it
ESPN’s @JeffPassan on Bob Nutting’s reputation around baseball as the owner of the Pittsburgh Pirates via @937theFan: “I think he’s seen as somebody who has a passionate fanbase. Who has arguably the most beautiful stadium in Major League Baseball. And completely wasted it.”
WABC asked the mayoral candidates "Mets or Yankees?" Zohran Mamdani said "Mets", adding "I must admit I'm a bit of a fair-weather fan." Andrew Cuomo said "both."
Millennials and Gen Z are gonna be really good old people!! Feat Ismael Loutfi
My good friend, Richard Neer of WNEW FM & WFAN fame “helped me move” into my new home at Hilton Head, SC. Kramer wasn’t available.
WALK OFF!! - always nice to snag a win against a good pitcher - soto owns his former team - pete got called out at 2B and it didn’t even matter - small ball wins games - loudest i’ve ever heard citi field on a random tuesday - 25-7 at home?? METS WIN :)
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