ToGuLab
@techbiodd
We love biomolecular natural product chemistry - from compound / pathway discovery to elucidation of biosyntheses and application of enzymes in total synthesis!
قد يعجبك
Check out in our latest issue the Editorial of our 40th anniversary collection from our Executive Editor Katie Lim & Editorial Board Chair Tobias Gulder reflecting on the progress of the journal over the past four decades Read their full thoughts here🔽 pubs.rsc.org/en/content/art…
A beauty put together by our @TobiasMilzarek @Helmholtz_HIPS @Helmholtz_HZI. It summarizes a huge body of work by many on one of our favorite natural product classes, the sorbicillinoids! Thanks to @dfg_public for funding!
🔓Read this #OpenAccess review by @TobiasMilzarek & our Editorial Board Chair Tobias Gulder @techbiodd at @Helmholtz_HIPS in our latest issue looking at the structures, bioactivities, biosynthesis & synthesis of the fungal sorbicillinoids Find it below👇 pubs.rsc.org/en/content/art…
Fluoro-Fucosylation Enables the Interrogation of the Lea-LecB Interaction by Bio#NMRspectroscopy (Ryan Gilmour and co-workers) @GilmourLab #openaccess 🔓 onlinelibrary.wiley.com/doi/10.1002/an…
Expanding Polycyclic Tetramate Macrolactam (PoTeM) Core Structure Diversity by Chemo-Enzymatic Synthesis and Bioengineering (Tobias A. M. Gulder and co-workers) @ManuEinsiedler @sschneider_lab @techbiodd @Helmholtz_HIPS @Helmholtz_HZI #openaccess 🔓onlinelibrary.wiley.com/doi/10.1002/an…
Way to go @ManuEinsiedler, Sebastian Schuler and the entire team PoTeM!
What a nice pre-christmas present: This fascinating and complex project of my colleague and good friend Basti about extending PoTeM structural space using two different approaches; now published in ACIE! Challenging chemistry, but totally worth the effort! onlinelibrary.wiley.com/doi/10.1002/an…
onlinelibrary.wiley.com
Erweiterung der Vielfalt der Kernstruktur von Polycyclischen Tetramsäure‐Haltigen Makrolactamen...
Polycyclische Tetramsäure-haltige Makrolactame (PoTeMs) leiten sich vom Ornithin-basierten Lysobacteren A ab. Um das Kohlenstoffgerüst der PoTeM-Kernstruktur um eine CH2-Einheit zu erweitern, wurden...
What a nice pre-christmas present: This fascinating and complex project of my colleague and good friend Basti about extending PoTeM structural space using two different approaches; now published in ACIE! Challenging chemistry, but totally worth the effort! onlinelibrary.wiley.com/doi/10.1002/an…
onlinelibrary.wiley.com
Erweiterung der Vielfalt der Kernstruktur von Polycyclischen Tetramsäure‐Haltigen Makrolactamen...
Polycyclische Tetramsäure-haltige Makrolactame (PoTeMs) leiten sich vom Ornithin-basierten Lysobacteren A ab. Um das Kohlenstoffgerüst der PoTeM-Kernstruktur um eine CH2-Einheit zu erweitern, wurden...
…robialcellfactories.biomedcentral.com/.../s129... A new paper resulting from our collaboration with ICESI university in Colombia was just published by MCF. Factories. It concerns the optimization of secondary metabolite production during fermentation of an endopytic fungus. Congrats to all coauthors!
I am very proud to share a long story on lectins and biofilm imaging just published in @JACS_Au by Eva and Lisa in cooperation with many colleagues such as @AnneImberty @SueSK001 😍 #glycotime #chembio #AMR please have a look here: pubs.acs.org/doi/10.1021/ja…
So glad to see our work about the synthesis and biological activity characterisation of benzodiazepinediones resulting in the discovery and fine-tuning of their interference with bacterial quorum sensing now out in @OrgBiomolChem! pubs.rsc.org/en/content/art… Hope you enjoy the read!
![ManuEinsiedler's tweet card. Benzo[1,4]diazepines show a large diversity of biological activities and are still commonly used as medications against a broad range of diseases. Within our research in the field of chemo-enzymatic...](https://pbs.twimg.com/card_img/1988796363547480064/pyMPOTfE?format=jpg&name=orig)
Thanks for the invitation by @CarlNising to visit the @BayerDialog site in Wuppertal and giving a @GDCh_aktuell lecture there yesterday! This was an amazing day!
Congratulations Lena and lab @barra_lena! What a beautiful piece of work to start your independent publication record! Very much looking forward to everything to come from your team over the next decades 👍
Happy to share our first independent work just out @angew_chem: Natural methyl analogs of central sesquiterpenes widespread in actinobacteria! Exciting enzyme chemistry. Curious why they exist. A hidden "magic methyl effect" in the terpene world? onlinelibrary.wiley.com/doi/10.1002/an…
📢 Our first paper on hydrogen isotope exchange in structured solutions is out in @angew_chem 🍾 Many thanks to Yang, Jonny & Martin and the labs @RalfTonner and Asmis! This was only possible with such a great team @123H_RTG! 👏 onlinelibrary.wiley.com/doi/10.1002/an…
🎉A great day at the @NatProdReports Editorial Board meeting. Wonderful to see so many of the board in person to talk about the exciting future of the journal! Looking forward to listening to their talks tomorrow at the journal's 40th anniversary symposium
sciencedirect.com/science/articl… Another paper on new bioactive compounds from a rare European basidiomycete was just accepted by Fitoterapia. Congrats to @WinnieSum6 and all other co-authors and thanks for funding from @AvHStiftung and @DAAD_Germany !
⏳Its the final day for you to register to attend the special one day symposium celebrating @NatProdReports 40th anniversary held @Helmholtz_HIPS! Join us in the celebrations and register for free here🔽 rsc.li/npr40
🚨Don't miss your chance to atttend the special one day symposium celebrating @NatProdReports 40th anniversary held @Helmholtz_HIPS! Join us in the celebrations with talks across natural products research 📅Register for free by October 18th▶rsc.li/npr40
Happy that this is finally online! Genetic code expansion approaches to decipher the ubiquitin code @ACSChemRev Many congratulations to Vera, Max and Marco! @VeraWanka @MaxFottner @MarkoCigler 🥂🎉🥳 pubs.acs.org/doi/10.1021/ac…
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