Dave Jackson
@unreal_dave
mountains | molecules
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Thank you @bradloncar for the chance to tell how my initial discovery of CpG DNA (TLR9 agonist) 30 yrs ago led to vidutolimod, and how at Zola Therapeutics we've discovered novel RNA/DNA TLR7/8/9 agonists that appear to be a huge leap forward for cancer immunotherapy!
𝐓𝐡𝐞 𝐒𝐭𝐮𝐝𝐢𝐨 𝐚𝐭 𝐊𝐞𝐧𝐝𝐚𝐥𝐥 𝐒𝐪𝐮𝐚𝐫𝐞: Biotech veteran @ArtKrieg explains the science behind his newest immunotherapy company, Zola Therapeutics, which uses both RNA and DNA agonists delivered in an LNP. Full video: biotechtv.com/post/zola-ther…
Any way you slice it whether it is #RunningAtlas, #WalkingAtlas or #BikingAtlas - we welcome you to join us for some pre-Pi Day miles tomorrow morning at 7am departing from the Tech Sq Quad.
Pharma BD landscape within the molecular glue space With last week's Lilly / Magnet Biomedicine $1.3B deal, we're now up to 24 deals led by big pharma since 2020, totaling ~$27B in total disclosed deal values What's causing all of these companies to jump in? Some thoughts:…
#RunningAtlas, #BikingAtlas, #WalkingAtlas is on for tomorrow 2/27 at 7am. We will head out for the Tech Sq Quad. Join us for some potentially wet but mild (aka #fakespring) miles!
It's winter in New England, of course we are still on! Join us tomorrow morning in a wet Tech Sq Quad at 7am for #RunningAtlas, #WalkingAtlas, #BikingAtlas
Get your miles in before the snow/sleet falls! Join us at 7am tomorrow leaving from the Tech Sq Quad. All levels and paces welcome. #RunningAtlas #BikingAtlas #WalkingAtlas
Congratulations to the team at #FlagshipFounded @Empress_Tx on being named to @cenmag’s list of startups to watch. #10StartUpsToWatch Learn more about how Empress is converging the power of genetics and a digital data-driven AI approach to revolutionize small molecule drug…
We are excited to share that Empress Therapeutics has been named to @cenmag’s annual list of #10StartUpsToWatch! This recognition highlights our unique #Chemilogics platform that applies the power of genetics to access a previously untapped universe of chemistry-based drug leads…
Most mammals rely on fats and carbohydrates to fuel exercise, but what about blood-sucking vampire bats? Scientists put them on a treadmill to find out. Learn more: newscientist.com/article/245453…
Great work by my friend and former coworker!
Fascinating research alert from Emily Mevers! @MeversLab focuses on natural products. Recent work includes psychedelic millipedes and their unique chemical defenses! These tiny creatures reveal new insights into chemical ecology and defense mechanisms. link.springer.com/article/10.100…
link.springer.com
The Chemistry of the Defensive Secretions of Three Species of Millipedes in the Genus Brachycybe
Journal of Chemical Ecology - Millipedes have long been known to produce a diverse array of chemical defense agents that deter predation. These compounds, or their precursors, are stored in high...
The Fatal Mushroom Neurotoxin Muscarine is Released from a Harmless Phosphorylated Precursor upon Cellular Injury - Dörner - Angewandte Chemie International Edition - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/an…
Stop using ‘summer’, ‘winter’ and the rest when inviting researchers to events — it’s a small step, but it’s necessary and inclusive go.nature.com/4dUMxT0
What: #RunningAtlas, #WalkingAtlas, #BikingAtlas When: Tomorrow, Thursday, October 17th at 7am Where: Departing from the Tech Sq Quad Join us!
The weather may feel a bit different tomorrow but the time and place remain the same! Departing from Tech Sq Quad at 7am. #JoinUs #RunningAtlas #BikingAtlas #WalkingAtlas
Dear friends we are looking for Scientific Program Manager for our @HarvardMSI Microbial Sciences Intiative. Forward this on or read below if you're interested. @HarvardMSI is a microbiology-centered initiative that brings together scholars from Harvard and beyond. We host…
Never underestimate a diiron enzyme. Congrats @sanjoyadak90 for bringing the nitrile synthase AetD to life with @Drennan_lab, Maria-Eirini Pandelia, and Ken Houk labs. Published today @NatureChemistry nature.com/articles/s4155…
FACULTY JOB | @AnatomyNeurobio @UCIrvine We are excited to announce a new TT faculty search at the Asst/Assoc level. Emphasis is broadly on neural circuits. UCI has a fantastic neuroscience program, and I'm happy to answer Qs. Apply by 10/31: recruit.ap.uci.edu/JPF09237 Please RT
Check out another one of our open access paper. This one was a real team effort with contributions from @apheloria, @ImperfectFunGuy, and Tappey Jones. Congrats Paige Banks on the first, first author publication and to all involved! link.springer.com/article/10.100…
link.springer.com
The Chemistry of the Defensive Secretions of Three Species of Millipedes in the Genus Brachycybe
Journal of Chemical Ecology - Millipedes have long been known to produce a diverse array of chemical defense agents that deter predation. These compounds, or their precursors, are stored in high...
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