Research from @NikouSpyridoula, Parker, and @thenagliklab in human cells and mice elucidates how #candidalysin – a toxin produced by the yeast pathogen #Calbicans – elicits distinct cellular responses through p38 and #EGFR. @TheCrick fcld.ly/11ql443

scisignal's tweet image. Research from @NikouSpyridoula, Parker, and @thenagliklab in human cells and mice elucidates how #candidalysin – a toxin produced by the yeast pathogen #Calbicans – elicits distinct cellular responses through p38 and #EGFR. @TheCrick fcld.ly/11ql443

Bulut et al. When platelets meet #candidalysin: “We just Wnt to have fun” Read the article here👉 doi.org/10.1111/all.15… See more papers: journalallergy.com/Groundbreaking… @dominjor #asthma #Allergy_journal

AllergyEaaci's tweet image. Bulut et al. When platelets meet #candidalysin: “We just Wnt to have fun”

Read the article here👉 doi.org/10.1111/all.15…

See more papers: journalallergy.com/Groundbreaking…
@dominjor #asthma #Allergy_journal

#Candidalysin unraveled more, read what @Swidergall_lab from @HarborUCLA, @theRAD__lab from @unibirmingham, @mpm_hki from LeibnizHKI and @thenagliklab from @KingsCollegeLon have to say. But why are studies on candidalysin not in WT SC5314 ? @IDSAInfo academic.oup.com/jid/advance-ar…


#mdpitoxins Editor’s Choice Articles🔍 🛎️"#Candidalysin Is the Hemolytic Factor of Candida albicans" by Prof. Bernhard Hube et al. 👉Link: mdpi.com/2008114

Toxins_MDPI's tweet image. #mdpitoxins Editor’s Choice Articles🔍 
🛎️"#Candidalysin Is the Hemolytic Factor of Candida albicans" by Prof. Bernhard Hube et al. 
👉Link: mdpi.com/2008114

We recommend reading this interesting article published in #mdpitoxins recently: "Evaluation of a Novel Synthetic Peptide Derived from Cytolytic #Mycotoxin #Candidalysin" First author: Dr. Pedro Henrique de Oliveira Cardoso. Welcome to read and share! @UCDBoficial @OcFrancosLab

Toxins_MDPI's tweet image. We recommend reading this interesting article published in #mdpitoxins recently:
"Evaluation of a Novel Synthetic Peptide Derived from Cytolytic #Mycotoxin #Candidalysin" 
First author: Dr. Pedro Henrique de Oliveira Cardoso. Welcome to read and share!
@UCDBoficial  @OcFrancosLab

Selene Mogavero & team trace the steps of #Candidalysin from fungus to host. Read this @CellMicrobiol Editor's Choice Microreview: ow.ly/CRvE50GpVJh #OpenAccess

WileyLifeSci's tweet image. Selene Mogavero & team trace the steps of #Candidalysin from fungus to host.

Read this @CellMicrobiol Editor's Choice Microreview: ow.ly/CRvE50GpVJh

#OpenAccess

Platelets also precluded pulmonary hemorrhage from fungal lung invasion. Thus, in addition to hemostasis, #platelets promoted protection against C. albicans airway mycosis through a pathway involving #candidalysin, GP1b alpha and Dkk-1, which promotes #Th2 and #Th17 responses 4/4


New #mBio minireview: #Candidalysin biology and activation of host cells. #Candida #albicans doi.org/10.1128/mbio.0…

mbiojournal's tweet image. New #mBio minireview: #Candidalysin biology and activation of host cells. #Candida #albicans doi.org/10.1128/mbio.0…

Fascinating discovery of #candidalysin in #Candida #albicans a #peptide #toxin

C. albicans attacks human cells by releasing a toxic peptide called candidalysin (£) bit.ly/1RrS9XD

NatureNV's tweet image. C. albicans attacks human cells by releasing a toxic peptide called candidalysin (£) bit.ly/1RrS9XD


Fungal infections are becoming more common. A new review in #IDDB explores #Candidalysin: From Mechanism of Action to #Biomarker Development and Therapeutic Response. Yao-Qi Chen; Qian Li; Tian-Yi Zhang; Ning-Ning Liu. #IDDB doi.org/10.36401/IDDB-…

InnoJournals's tweet image. Fungal infections are becoming more common. A new review in #IDDB explores #Candidalysin: From Mechanism of Action to #Biomarker Development and Therapeutic Response. Yao-Qi Chen; Qian Li; Tian-Yi Zhang; Ning-Ning Liu. #IDDB 
doi.org/10.36401/IDDB-…

All three candidalysins have different amino acid sequences but are a-helical and amphipathic. Notably, the C. dub and C. trop candidalysins were more potent in vitro at inducing cell damage, calcium influx, MAPK signalling and cytokine responses than C. alb #candidalysin.


At todays poster session 2 at the #HFP2024: Tim will present his work about our favorite cytolytic toxin #candidalysin and how it promotes #Candida's gut commensalism!

mpm_hki's tweet image. At todays poster session 2 at the #HFP2024: Tim will present his work about our favorite cytolytic toxin #candidalysin and how it promotes #Candida's gut commensalism!

#Candidalysin from C. albicans is fascinating and a key to unlocking #guthealth!

ASM Candida meeting at Providence RI. Jonathan Richardson shows that candidalysin forms oligomers in presence of lipids. @HubWTSA @MRCcmm #ASMCandida @ASMicrobiology

neil_gow's tweet image. ASM Candida meeting at Providence RI. Jonathan Richardson shows that candidalysin forms oligomers in presence of lipids.  @HubWTSA @MRCcmm #ASMCandida @ASMicrobiology


#TBT in #IDDB : This 2020 review article by Chen et al. discusses Candidalysin - mechanism of action, biomarker development, and therapeutic response doi.org/10.36401/IDDB-… #Candidalysin #FungalInfection @ZKozlakidis @Innovativehci @InnoJournals @drrdwa

EditorsIddb's tweet image. #TBT in #IDDB : This 2020 review article by Chen et al. discusses Candidalysin - mechanism of action, biomarker development, and therapeutic response
doi.org/10.36401/IDDB-…
#Candidalysin #FungalInfection
@ZKozlakidis  @Innovativehci  @InnoJournals  @drrdwa

Magnificent piece of work by @aps_hki showing that albumin can neutralize hydrophobic toxins including #candidalysin, @Mark_Gresnigt, @mpm_hki, @LabMoyes, @jemyho. Thanks for involving us. journals.asm.org/doi/10.1128/mB…


The toxin #Candidalysin of the yeast Candida albicans is embedded in the unusual protein structure Ece1 during infections. Researchers from @LeibnizHKI have now decoded the structure, paving the way for #nanobody-based therapies against vaginal candidiasis. @microverse_exc


New #mBio minireview: #Candidalysin biology and activation of host cells. #Candida #albicans doi.org/10.1128/mbio.0…

mbiojournal's tweet image. New #mBio minireview: #Candidalysin biology and activation of host cells. #Candida #albicans doi.org/10.1128/mbio.0…

Delighted to announce our publication on the presence of active #candidalysin in #Candida EVs. Great work by Sejeong Lee @antzela_tsavou and our collaborators @davidrandes @ZarnowskiRobert @mpm_hki @JPRichardsonLab journals.asm.org/doi/epub/10.11…


👏The first out of 4 publications honored with the 2024 medac Research Award uncovered how #Ece1 controls the release of #candidalysin in Candida albicans, enabling fungal infections. Read more in @NatureMicrobiol: nature.com/articles/s4156…

LeibnizHKI's tweet image. 👏The first out of 4 publications honored with the 2024 medac Research Award uncovered how #Ece1 controls the release of #candidalysin in Candida albicans, enabling fungal infections.
Read more in @NatureMicrobiol: nature.com/articles/s4156…

Check out Tim Schille's poster at today's poster session of the #DMykG2024: He presents the role of #candidalysin and the other Ece1 peptides in fungal gut commensalism. 👉 Poster PI-21 👉 Also check out the paper: nature.com/articles/s4158… @DmykGeV @LeibnizHKI @microverse_exc

mpm_hki's tweet image. Check out Tim Schille's poster at today's poster session of the #DMykG2024: He presents the role of #candidalysin and the other Ece1 peptides in fungal gut commensalism. 
👉 Poster PI-21
👉 Also check out the paper: nature.com/articles/s4158…
@DmykGeV @LeibnizHKI @microverse_exc

At todays poster session 2 at the #HFP2024: Tim will present his work about our favorite cytolytic toxin #candidalysin and how it promotes #Candida's gut commensalism!

mpm_hki's tweet image. At todays poster session 2 at the #HFP2024: Tim will present his work about our favorite cytolytic toxin #candidalysin and how it promotes #Candida's gut commensalism!

The toxin #Candidalysin of the yeast Candida albicans is embedded in the unusual protein structure Ece1 during infections. Researchers from @LeibnizHKI have now decoded the structure, paving the way for #nanobody-based therapies against vaginal candidiasis. @microverse_exc


#mdpitoxins Editor’s Choice Articles🔍 🛎️"#Candidalysin Is the Hemolytic Factor of Candida albicans" by Prof. Bernhard Hube et al. 👉Link: mdpi.com/2008114

Toxins_MDPI's tweet image. #mdpitoxins Editor’s Choice Articles🔍 
🛎️"#Candidalysin Is the Hemolytic Factor of Candida albicans" by Prof. Bernhard Hube et al. 
👉Link: mdpi.com/2008114

Very proud to be part of this work! Finally we know the function of the non-#candidalysin peptides! @mpm_hki @JPRichardsonLab @emi1ypriest trebuchet.public.springernature.app/get_content/46…


Delighted to be part of this excellent work: Nanobody-mediated neutralization of #candidalysin prevents epithelial damage and inflammatory responses that drive vulvovaginal candidiasis pathogenesis! @mpm_hki @aps_hki @emi1ypriest @antzela_tsavou journals.asm.org/doi/10.1128/mb…


Brilliant study from David Corry @ImmunoDocs. C. albicans is cleared from the brain through innate mechanisms involving Saps, #candidalysin, Aβ, and CD11b. @JPRichardsonLab @LortalLea @mpm_hki @KingsCollegeLon cell.com/cell-reports/p…


#candidalysin promotes the stimulation of neutrophil extracellular traps (NETs) via ROS- and Ca2+-dependent pathways! @emboreports. Excellent study by @UrbanConstantin @LucasUnger12. Fortunate to have contributed with @mpm_hki @KingsCollegeLon embopress.org/doi/full/10.15…

thenagliklab's tweet image. #candidalysin promotes the stimulation of neutrophil extracellular traps (NETs) via ROS- and Ca2+-dependent pathways! @emboreports. Excellent study by @UrbanConstantin @LucasUnger12. Fortunate to have contributed with @mpm_hki @KingsCollegeLon 
embopress.org/doi/full/10.15…

#TBT in #IDDB : This 2020 review article by Chen et al. discusses Candidalysin - mechanism of action, biomarker development, and therapeutic response doi.org/10.36401/IDDB-… #Candidalysin #FungalInfection @ZKozlakidis @Innovativehci @InnoJournals @drrdwa

EditorsIddb's tweet image. #TBT in #IDDB : This 2020 review article by Chen et al. discusses Candidalysin - mechanism of action, biomarker development, and therapeutic response
doi.org/10.36401/IDDB-…
#Candidalysin #FungalInfection
@ZKozlakidis  @Innovativehci  @InnoJournals  @drrdwa

Have you read this #IDDB review article from 2020? "Candidalysin: From Mechanism of Action to Biomarker Development and Therapeutic Response"" by Chen et al. doi.org/10.36401/IDDB-… #candidalysin #fungalinfection @ZKozlakidis

EditorsIddb's tweet image. Have you read this #IDDB review article from 2020? "Candidalysin: From Mechanism of Action to Biomarker Development and Therapeutic Response"" by Chen et al. 
doi.org/10.36401/IDDB-…
#candidalysin #fungalinfection 
@ZKozlakidis

We recommend reading this interesting article published in #mdpitoxins recently: "Evaluation of a Novel Synthetic Peptide Derived from Cytolytic #Mycotoxin #Candidalysin" First author: Dr. Pedro Henrique de Oliveira Cardoso. Welcome to read and share! @UCDBoficial @OcFrancosLab

Toxins_MDPI's tweet image. We recommend reading this interesting article published in #mdpitoxins recently:
"Evaluation of a Novel Synthetic Peptide Derived from Cytolytic #Mycotoxin #Candidalysin" 
First author: Dr. Pedro Henrique de Oliveira Cardoso. Welcome to read and share!
@UCDBoficial  @OcFrancosLab

ไม่พบผลลัพธ์สำหรับ "#candidalysin"

Research from @NikouSpyridoula, Parker, and @thenagliklab in human cells and mice elucidates how #candidalysin – a toxin produced by the yeast pathogen #Calbicans – elicits distinct cellular responses through p38 and #EGFR. @TheCrick fcld.ly/11ql443

scisignal's tweet image. Research from @NikouSpyridoula, Parker, and @thenagliklab in human cells and mice elucidates how #candidalysin – a toxin produced by the yeast pathogen #Calbicans – elicits distinct cellular responses through p38 and #EGFR. @TheCrick fcld.ly/11ql443

Bulut et al. When platelets meet #candidalysin: “We just Wnt to have fun” Read the article here👉 doi.org/10.1111/all.15… See more papers: journalallergy.com/Groundbreaking… @dominjor #asthma #Allergy_journal

AllergyEaaci's tweet image. Bulut et al. When platelets meet #candidalysin: “We just Wnt to have fun”

Read the article here👉 doi.org/10.1111/all.15…

See more papers: journalallergy.com/Groundbreaking…
@dominjor #asthma #Allergy_journal

We recommend reading this interesting article published in #mdpitoxins recently: "Evaluation of a Novel Synthetic Peptide Derived from Cytolytic #Mycotoxin #Candidalysin" First author: Dr. Pedro Henrique de Oliveira Cardoso. Welcome to read and share! @UCDBoficial @OcFrancosLab

Toxins_MDPI's tweet image. We recommend reading this interesting article published in #mdpitoxins recently:
"Evaluation of a Novel Synthetic Peptide Derived from Cytolytic #Mycotoxin #Candidalysin" 
First author: Dr. Pedro Henrique de Oliveira Cardoso. Welcome to read and share!
@UCDBoficial  @OcFrancosLab

New #mBio minireview: #Candidalysin biology and activation of host cells. #Candida #albicans doi.org/10.1128/mbio.0…

mbiojournal's tweet image. New #mBio minireview: #Candidalysin biology and activation of host cells. #Candida #albicans doi.org/10.1128/mbio.0…

Selene Mogavero & team trace the steps of #Candidalysin from fungus to host. Read this @CellMicrobiol Editor's Choice Microreview: ow.ly/CRvE50GpVJh #OpenAccess

WileyLifeSci's tweet image. Selene Mogavero & team trace the steps of #Candidalysin from fungus to host.

Read this @CellMicrobiol Editor's Choice Microreview: ow.ly/CRvE50GpVJh

#OpenAccess

#mdpitoxins Editor’s Choice Articles🔍 🛎️"#Candidalysin Is the Hemolytic Factor of Candida albicans" by Prof. Bernhard Hube et al. 👉Link: mdpi.com/2008114

Toxins_MDPI's tweet image. #mdpitoxins Editor’s Choice Articles🔍 
🛎️"#Candidalysin Is the Hemolytic Factor of Candida albicans" by Prof. Bernhard Hube et al. 
👉Link: mdpi.com/2008114

#TBT in #IDDB : This 2020 review article by Chen et al. discusses Candidalysin - mechanism of action, biomarker development, and therapeutic response doi.org/10.36401/IDDB-… #Candidalysin #FungalInfection @ZKozlakidis @Innovativehci @InnoJournals @drrdwa

EditorsIddb's tweet image. #TBT in #IDDB : This 2020 review article by Chen et al. discusses Candidalysin - mechanism of action, biomarker development, and therapeutic response
doi.org/10.36401/IDDB-…
#Candidalysin #FungalInfection
@ZKozlakidis  @Innovativehci  @InnoJournals  @drrdwa

At todays poster session 2 at the #HFP2024: Tim will present his work about our favorite cytolytic toxin #candidalysin and how it promotes #Candida's gut commensalism!

mpm_hki's tweet image. At todays poster session 2 at the #HFP2024: Tim will present his work about our favorite cytolytic toxin #candidalysin and how it promotes #Candida's gut commensalism!

Fungal infections are becoming more common. A new review in #IDDB explores #Candidalysin: From Mechanism of Action to #Biomarker Development and Therapeutic Response. Yao-Qi Chen; Qian Li; Tian-Yi Zhang; Ning-Ning Liu. #IDDB doi.org/10.36401/IDDB-…

InnoJournals's tweet image. Fungal infections are becoming more common. A new review in #IDDB explores #Candidalysin: From Mechanism of Action to #Biomarker Development and Therapeutic Response. Yao-Qi Chen; Qian Li; Tian-Yi Zhang; Ning-Ning Liu. #IDDB 
doi.org/10.36401/IDDB-…

Check out Tim Schille's poster at today's poster session of the #DMykG2024: He presents the role of #candidalysin and the other Ece1 peptides in fungal gut commensalism. 👉 Poster PI-21 👉 Also check out the paper: nature.com/articles/s4158… @DmykGeV @LeibnizHKI @microverse_exc

mpm_hki's tweet image. Check out Tim Schille's poster at today's poster session of the #DMykG2024: He presents the role of #candidalysin and the other Ece1 peptides in fungal gut commensalism. 
👉 Poster PI-21
👉 Also check out the paper: nature.com/articles/s4158…
@DmykGeV @LeibnizHKI @microverse_exc

One of the highlights of MPM research is of course #candidalysin! Annika shared with the audience some new discoveries related to this interesting #fungal #toxin! #candida

mpm_hki's tweet image. One of the highlights of MPM research is of course #candidalysin! Annika shared with the audience some new discoveries related to this interesting #fungal #toxin! #candida

Stefania Vaga is now at The Human Microbiome Symposium #EEmicrobiome presenting our research on the effects of #Ece1 and #candidalysin on the gene-protein-reaction #network, by applying #SystemsBiology methods. @EMBLEvents #hostfungalinteractions

sysbiomelab's tweet image. Stefania Vaga is now at The Human Microbiome Symposium #EEmicrobiome presenting our research on the effects of #Ece1 and #candidalysin on the gene-protein-reaction #network, by applying #SystemsBiology methods. @EMBLEvents #hostfungalinteractions

Have you read this #IDDB review article from 2020? "Candidalysin: From Mechanism of Action to Biomarker Development and Therapeutic Response"" by Chen et al. doi.org/10.36401/IDDB-… #candidalysin #fungalinfection @ZKozlakidis

EditorsIddb's tweet image. Have you read this #IDDB review article from 2020? "Candidalysin: From Mechanism of Action to Biomarker Development and Therapeutic Response"" by Chen et al. 
doi.org/10.36401/IDDB-…
#candidalysin #fungalinfection 
@ZKozlakidis

#candidalysin is indeed crucial for host cell damage, but what are the other Ece1 peptides doing? Rita showed her latest data on their role in fungal biology and host interaction at #DGHMVAAM20 in Leipzig

mpm_hki's tweet image. #candidalysin is indeed crucial for host cell damage, but what are the other Ece1 peptides doing? Rita showed her latest data on their role in fungal biology and host interaction at #DGHMVAAM20 in Leipzig

👏The first out of 4 publications honored with the 2024 medac Research Award uncovered how #Ece1 controls the release of #candidalysin in Candida albicans, enabling fungal infections. Read more in @NatureMicrobiol: nature.com/articles/s4156…

LeibnizHKI's tweet image. 👏The first out of 4 publications honored with the 2024 medac Research Award uncovered how #Ece1 controls the release of #candidalysin in Candida albicans, enabling fungal infections.
Read more in @NatureMicrobiol: nature.com/articles/s4156…

#candidalysin drives allergic airway disease/#asthma in #Candida infections! Fantastic study by the David Corry lab (@bcmhouston) in @ImmunityCP. So pleased to be part of this together with @mpm_hki, @KingsCollegeLon. Quick thread 1/4 authors.elsevier.com/c/1djN43qNrUmR…

thenagliklab's tweet image. #candidalysin drives allergic airway disease/#asthma in #Candida infections! Fantastic study by the David Corry lab (@bcmhouston) in @ImmunityCP. So pleased to be part of this together with @mpm_hki, @KingsCollegeLon. Quick thread 1/4
authors.elsevier.com/c/1djN43qNrUmR…

Our postdoc Selene Mogavero entertained the audience with her talk about fungal toxin candidalysin // Statusworkshop of DGHM-Fachgruppe “Eukaryotic Pathogens” in Berlin #candidalysin #candida #fungalpathogens

mpm_hki's tweet image. Our postdoc Selene Mogavero entertained the audience with her talk about fungal toxin candidalysin // Statusworkshop of DGHM-Fachgruppe “Eukaryotic Pathogens” in Berlin #candidalysin #candida #fungalpathogens

@OWMHepworth presenting her PhD work on #candidalysin’s mechanism of toxicity at #LakesidePTE2022!

thenagliklab's tweet image. @OWMHepworth presenting her PhD work on #candidalysin’s mechanism of toxicity at #LakesidePTE2022!

Very proud of @OWMHepworth for delivering her offered talk on #candidalysin oligomeric structures at #bsmm2022! Great job!

thenagliklab's tweet image. Very proud of @OWMHepworth for delivering her offered talk on #candidalysin oligomeric structures at #bsmm2022! Great job!

#candidalysin promotes the stimulation of neutrophil extracellular traps (NETs) via ROS- and Ca2+-dependent pathways! @emboreports. Excellent study by @UrbanConstantin @LucasUnger12. Fortunate to have contributed with @mpm_hki @KingsCollegeLon embopress.org/doi/full/10.15…

thenagliklab's tweet image. #candidalysin promotes the stimulation of neutrophil extracellular traps (NETs) via ROS- and Ca2+-dependent pathways! @emboreports. Excellent study by @UrbanConstantin @LucasUnger12. Fortunate to have contributed with @mpm_hki @KingsCollegeLon 
embopress.org/doi/full/10.15…

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