#gprc5d search results

1-2> Matching modality to mechanism. The title above is something I've often commented on on Twitter, so it was nice to see. For example, #BMS has seen #GPRC5D as a more appropriate modality for cell therapy than bispecific antibodies, though I don't know the specific reasons.

onco_park's tweet image. 1-2> Matching modality to mechanism.
The title above is something I've often commented on on Twitter, so it was nice to see. For example, #BMS has seen #GPRC5D as a more appropriate modality for cell therapy than bispecific antibodies, though I don't know the specific reasons.

Bristol Myers Squibb $BMY Announces First Disclosures and New Data at #ASH22, Demonstrating Commitment to Raising Standards in Treatment Through Broad Multiple Myeloma Portfolio #GPRC5D CAR-T / Abecma / #BCMA TCE alnuctamab / #cellmods businesswire.com/news/home/2022…

BertrandBio's tweet image. Bristol Myers Squibb $BMY Announces First Disclosures and New Data at #ASH22, Demonstrating Commitment to Raising Standards in Treatment Through Broad Multiple Myeloma Portfolio #GPRC5D CAR-T / Abecma / #BCMA TCE alnuctamab / #cellmods businesswire.com/news/home/2022…
BertrandBio's tweet image. Bristol Myers Squibb $BMY Announces First Disclosures and New Data at #ASH22, Demonstrating Commitment to Raising Standards in Treatment Through Broad Multiple Myeloma Portfolio #GPRC5D CAR-T / Abecma / #BCMA TCE alnuctamab / #cellmods businesswire.com/news/home/2022…
BertrandBio's tweet image. Bristol Myers Squibb $BMY Announces First Disclosures and New Data at #ASH22, Demonstrating Commitment to Raising Standards in Treatment Through Broad Multiple Myeloma Portfolio #GPRC5D CAR-T / Abecma / #BCMA TCE alnuctamab / #cellmods businesswire.com/news/home/2022…
BertrandBio's tweet image. Bristol Myers Squibb $BMY Announces First Disclosures and New Data at #ASH22, Demonstrating Commitment to Raising Standards in Treatment Through Broad Multiple Myeloma Portfolio #GPRC5D CAR-T / Abecma / #BCMA TCE alnuctamab / #cellmods businesswire.com/news/home/2022…

#Talquetamab is a bispecific antibody. The cancer-targeting part binds to #GPRC5D, a protein found on some normal cells but abundant on #myeloma cells, making it a good drug target. The $JNJ drug could become the first one approved for targeting GPRC5D.


BMS-986393 (#GPRC5D CAR-T). We will need to look at the adverse event profile by dose. ash.confex.com/ash/2023/webpr…

onco_park's tweet image. BMS-986393 (#GPRC5D CAR-T).
We will need to look at the adverse event profile by dose.
ash.confex.com/ash/2023/webpr…
onco_park's tweet image. BMS-986393 (#GPRC5D CAR-T).
We will need to look at the adverse event profile by dose.
ash.confex.com/ash/2023/webpr…

⚡️ La thérapie #CAR_Tcell 🩸 ciblée par l'antigène #GPRC5D induit une forte réponse dans le #MyélomeMultiple 👉#MCARH109, ​​une thérapie #CAR_T 🩸 ciblant l'antigène GPRC5D, a généré des rémissions chez 70,6 % des patients atteints de #Myélome multiple R/R www2.onclive.com/view/gprc5d-an…

jyves94's tweet image. ⚡️ La thérapie #CAR_Tcell 🩸 ciblée par l'antigène #GPRC5D induit une forte réponse dans le #MyélomeMultiple
👉#MCARH109, ​​une thérapie #CAR_T 🩸 ciblant l'antigène GPRC5D, a généré des rémissions chez 70,6 % des patients atteints de #Myélome multiple R/R
www2.onclive.com/view/gprc5d-an…

⚡️#TheLancet 👉Cellules #CAR_T #GPRC5D (#OriCAR_017) chez des patients atteints d’un #MyélomeMultiple #POLARIS en R/R, 1er essai de #Phase1 chez l’homme 👉La thérapie par #CAR_T ciblant #BCMA a montré une activité dans le traitement du #MyélomeMultiple R/R thelancet.com/journals/lanha…

jyves94's tweet image. ⚡️#TheLancet
👉Cellules #CAR_T #GPRC5D (#OriCAR_017) chez des patients atteints d’un #MyélomeMultiple #POLARIS en R/R, 1er essai de #Phase1 chez l’homme
👉La thérapie par #CAR_T ciblant #BCMA a montré une activité dans le traitement du #MyélomeMultiple R/R
thelancet.com/journals/lanha…

Les chercheurs espéraient que la protéine #GPRC5D pourrait offrir une façon d'amener le système immunitaire à traquer & à détruire les cellules de #MyélomeMultiple 🩸 👉Les résultats d'une étude de Phase 2 sur un #AnticorpsBispécifique ciblant cette protéine viennent le confirmer

🩸#NEWORLEANS 🇺🇸- « Nous avons une nouvelle cible » : un #AnticorpsBispécifique pour le #MyélomeMultiple 🩸 réussit un essai à mi-parcours #ASH2022 #GPRC5D statnews.com/2022/12/10/bis…

jyves94's tweet image. 🩸#NEWORLEANS 🇺🇸- « Nous avons une nouvelle cible » : un #AnticorpsBispécifique pour le #MyélomeMultiple 🩸 réussit un essai à mi-parcours
#ASH2022 #GPRC5D
statnews.com/2022/12/10/bis…


🩸 Le #Talquetamab est un anticorps bispécifique expérimental, prêt à l'emploi, qui redirige les lymphocytes T ciblant à la fois le #GPRC5D, une nouvelle cible médicamenteuse, sur les cellules de #Myélome_Multiple et le #CD3 sur les #LymphocytesT.

jyves94's tweet image. 🩸 Le #Talquetamab est un anticorps bispécifique expérimental, prêt à l'emploi, qui redirige les lymphocytes T ciblant à la fois le #GPRC5D, une nouvelle cible médicamenteuse, sur les cellules de #Myélome_Multiple et le #CD3 sur les #LymphocytesT.

Cela conduit à l'activation des #Cellules_T et à la lyse ultérieure des cellules exprimant #GPRC5D par la perforine sécrétée et diverses #Granzymes stockées dans les vésicules sécrétoires des cellules T cytotoxiques


🩸 L'essai de la thérapie #CAR_TCell ciblant le #GPRC5D montre son efficacité dans le #MyélomeMultiple résistant R/R, & révèle des #Rémissions chez 70,6 % des patients inscrits. 👉 Le #CAR_T a produit des résultats impressionnants ! #CARTCR #ImmunoTherapy buff.ly/3MdehGe

jyves94's tweet image. 🩸 L'essai de la thérapie #CAR_TCell ciblant le #GPRC5D montre son efficacité dans le #MyélomeMultiple résistant R/R, & révèle des #Rémissions chez 70,6 % des patients inscrits.
👉 Le #CAR_T a produit des résultats impressionnants !
#CARTCR #ImmunoTherapy
buff.ly/3MdehGe

#GPRC5D#CD3 に対する二重特異性抗体 #talquetamab が少なくとも3ラインの治療歴を有する成人の再発・難治性 #多発性骨髄腫 を対象に欧州で条件付き承認を獲得しました。 medical.nikkeibp.co.jp/leaf/all/cance…


#BMS 🇺🇸 a souligné son intention de lancer l’essai d’enregistrement de BMS-986393 (CC-95266; #GPRC5D #CAR_T ✂️) au S1 2024 ainsi que son intention de soumettre une IND pour l’enquête sur BMS-986353 (CC-97540 #CD19 NEX-T #CAR_T ✂️) dans la #ScléroseEnPlaques (#MS) en 09 2023


🩸 L'essai de #Phase1 #POLARIS ciblées par #GPRC5D a montré un taux de réponse global de 100 % pour #OriCAR_017, une nouvelle thérapie #CAR_Tcell avec une nouvelle cible dans le #MyélomeMultiple R/R. targetedonc.com/view/gprc5d-ta…

jyves94's tweet image. 🩸 L'essai de #Phase1 #POLARIS ciblées par #GPRC5D a montré un taux de réponse global de 100 % pour #OriCAR_017, une nouvelle thérapie #CAR_Tcell avec une nouvelle cible dans le #MyélomeMultiple R/R.
targetedonc.com/view/gprc5d-ta…

#EurekaTherapeutics Announces New England Journal of Medicine Publication of Clinical Study Demonstrating #GPRC5D as an Active Target for the Treatment of #MultipleMyeloma 1stoncology.com/blog/eureka-th…


Although the #GPRC5D gene is typically expressed in hair follicles, CD138-positive multiple myeloma cells have also been found to express GPRC5D. Learn more about the GPRC5D gene in its #BiologicalPathwayReview! hmpgloballearningnetwork.com/site/onc/biolo…

OncLearnNetwork's tweet image. Although the #GPRC5D gene is typically expressed in hair follicles, CD138-positive multiple myeloma cells have also been found to express GPRC5D. Learn more about the GPRC5D gene in its #BiologicalPathwayReview! hmpgloballearningnetwork.com/site/onc/biolo…

LucidQuest Updates > Hematology Today: CAR-T, Gene Therapy and Radioconjugates (Oct 6–13, 2025) dlvr.it/TNfK9P #BioPharmaandTechNews #HematologyNews #GPRC5D Comment below!

_timos_'s tweet image. LucidQuest Updates > Hematology Today: CAR-T, Gene Therapy and Radioconjugates (Oct 6–13, 2025) dlvr.it/TNfK9P #BioPharmaandTechNews #HematologyNews #GPRC5D Comment below!

CAR T-Cell therapy targeting #GPRC5D was found to be safe and effective for the treatment of relapsed/refractory #MM, according to a recent systematic meta-analysis. Learn more: hubs.ly/Q03mdDcN0

OncLearnNetwork's tweet image. CAR T-Cell therapy targeting #GPRC5D was found to be safe and effective for the treatment of relapsed/refractory #MM, according to a recent systematic meta-analysis. Learn more: hubs.ly/Q03mdDcN0

🔬AlpVHHs Pipeline Highlight: BS016 targeting GPRC5D for Multiple Myeloma (MM)! Advancing our VHH program against this key GPCR target in MM. Full details:👉alpvhhs.com/pipeline/ #Nanobody #VHH #GPRC5D #MultipleMyeloma #Biotech #AACR26

AlpVHHs's tweet image. 🔬AlpVHHs Pipeline Highlight:
BS016 targeting GPRC5D for Multiple Myeloma (MM)!  Advancing our VHH program against this key GPCR target in MM.  Full details:👉alpvhhs.com/pipeline/ 
#Nanobody #VHH #GPRC5D #MultipleMyeloma #Biotech #AACR26
AlpVHHs's tweet image. 🔬AlpVHHs Pipeline Highlight:
BS016 targeting GPRC5D for Multiple Myeloma (MM)!  Advancing our VHH program against this key GPCR target in MM.  Full details:👉alpvhhs.com/pipeline/ 
#Nanobody #VHH #GPRC5D #MultipleMyeloma #Biotech #AACR26

Enjoyed presenting @DAVAOnc #HemeDAVA meeting on #GPRC5D taste changes & #TALISMAN study & learnings. Great panel led by @AlGarfall & honored to be part of it with @DoctorAKrishnan @GKaurMD & Dr Raza. We've made progress but we also need to help patients live well too #MyCompany

MAWildgust's tweet image. Enjoyed presenting @DAVAOnc #HemeDAVA meeting on #GPRC5D taste changes & #TALISMAN study & learnings. Great panel led by @AlGarfall & honored to be part of it with @DoctorAKrishnan @GKaurMD & Dr Raza. We've made progress but we also need to help patients live well too #MyCompany
MAWildgust's tweet image. Enjoyed presenting @DAVAOnc #HemeDAVA meeting on #GPRC5D taste changes & #TALISMAN study & learnings. Great panel led by @AlGarfall & honored to be part of it with @DoctorAKrishnan @GKaurMD & Dr Raza. We've made progress but we also need to help patients live well too #MyCompany
MAWildgust's tweet image. Enjoyed presenting @DAVAOnc #HemeDAVA meeting on #GPRC5D taste changes & #TALISMAN study & learnings. Great panel led by @AlGarfall & honored to be part of it with @DoctorAKrishnan @GKaurMD & Dr Raza. We've made progress but we also need to help patients live well too #MyCompany

🔥 New: GPRC5D antibody [EPR2837641] (ab315808). ✅Recombinant Antibody ✅IHC on TMAs & myeloma ✅Leica BOND® RXvalidated ✅reliable supply See data: go to Abcam and search “ab315808.” #GPRC5D #IHC #RecombinantAntibody

advisains's tweet image. 🔥 New: GPRC5D antibody [EPR2837641] (ab315808). 
✅Recombinant Antibody
✅IHC on TMAs & myeloma
✅Leica BOND® RXvalidated
✅reliable supply
See data: go to Abcam and search “ab315808.”
#GPRC5D #IHC #RecombinantAntibody
advisains's tweet image. 🔥 New: GPRC5D antibody [EPR2837641] (ab315808). 
✅Recombinant Antibody
✅IHC on TMAs & myeloma
✅Leica BOND® RXvalidated
✅reliable supply
See data: go to Abcam and search “ab315808.”
#GPRC5D #IHC #RecombinantAntibody
advisains's tweet image. 🔥 New: GPRC5D antibody [EPR2837641] (ab315808). 
✅Recombinant Antibody
✅IHC on TMAs & myeloma
✅Leica BOND® RXvalidated
✅reliable supply
See data: go to Abcam and search “ab315808.”
#GPRC5D #IHC #RecombinantAntibody

LucidQuest Updates > Hematology Today: CAR-T, Gene Therapy and Radioconjugates (Oct 6–13, 2025) dlvr.it/TNfK9P #BioPharmaandTechNews #HematologyNews #GPRC5D Comment below!

_timos_'s tweet image. LucidQuest Updates > Hematology Today: CAR-T, Gene Therapy and Radioconjugates (Oct 6–13, 2025) dlvr.it/TNfK9P #BioPharmaandTechNews #HematologyNews #GPRC5D Comment below!

Thérapie par #CAR_T 🧬 ciblée par #GPRC5D (#CT071) pour le #MyélomeMultiple 🩸 R/R : 1er essai de phase 1 chez l’homme. Le taux de réponse est de 100 % (IC à 95 % : 83,2-100), avec une réponse complète ou un taux supérieur de 50 % (dix patients sur 20). thelancet.com/journals/lanha…

jyves94's tweet image. Thérapie par #CAR_T 🧬 ciblée par #GPRC5D (#CT071) pour le #MyélomeMultiple 🩸 R/R : 1er essai de phase 1 chez l’homme.
Le taux de réponse est de 100 % (IC à 95 % : 83,2-100), avec une réponse complète ou un taux supérieur de 50 % (dix patients sur 20).
thelancet.com/journals/lanha…

Fang Baijun's team from Henan Cancer Hospital published a review in the British Journal of Haematology, focusing on the GPRC5D target and explaining its key role in tumor biology. They also reviewed the cutting-edge progress such as CAR-T/NK cell therapy and ADC drugs.#GPRC5D

Oncologynewspro's tweet image. Fang Baijun's team from Henan Cancer Hospital published a review in the British Journal of Haematology, focusing on the GPRC5D target and explaining its key role in tumor biology. They also reviewed the cutting-edge progress such as CAR-T/NK cell therapy and ADC drugs.#GPRC5D
Oncologynewspro's tweet image. Fang Baijun's team from Henan Cancer Hospital published a review in the British Journal of Haematology, focusing on the GPRC5D target and explaining its key role in tumor biology. They also reviewed the cutting-edge progress such as CAR-T/NK cell therapy and ADC drugs.#GPRC5D
Oncologynewspro's tweet image. Fang Baijun's team from Henan Cancer Hospital published a review in the British Journal of Haematology, focusing on the GPRC5D target and explaining its key role in tumor biology. They also reviewed the cutting-edge progress such as CAR-T/NK cell therapy and ADC drugs.#GPRC5D

Sanofi’s SAR446523, a GPRC5D monoclonal antibody, earns orphan drug designation in the US for multiple myeloma sanofi.com/en/media-room/… #Sanofi #SAR446523 #GPRC5D #OrphanDrug #MultipleMyeloma #MonoclonalAntibody #Oncology #Hematology #RareDiseases


Syed Maaz Tariq, MD, shares results from a retrospective analysis showing non-BCMA CAR T-Cell therapies, such as #GPRC5D, demonstrate efficacy and safety for patients with relapsed/refractory #MM. Learn more: hubs.ly/Q03tTTZk0

OncLearnNetwork's tweet image. Syed Maaz Tariq, MD, shares results from a retrospective analysis showing non-BCMA CAR T-Cell therapies, such as #GPRC5D, demonstrate efficacy and safety for patients with relapsed/refractory #MM. Learn more: hubs.ly/Q03tTTZk0

Comparative Landscape of GPRC5D-Targeting and Next-Gen Therapies in Relapsed/Refractory Multiple Myeloma at @EHA_Hematology 2025. Follow us for the latest #EHA2025 updates: t.ly/6uoHY #LARVOL #Hematology #Myeloma #CancerResearch #Oncology #CancerData

Larvol's tweet image. Comparative Landscape of GPRC5D-Targeting and Next-Gen Therapies in Relapsed/Refractory Multiple Myeloma at @EHA_Hematology 2025.

Follow us for the latest #EHA2025 updates: t.ly/6uoHY

#LARVOL #Hematology #Myeloma #CancerResearch #Oncology #CancerData


CAR T-Cell therapy targeting #GPRC5D was found to be safe and effective for the treatment of relapsed/refractory #MM, according to a recent systematic meta-analysis. Learn more: hubs.ly/Q03mdDcN0

OncLearnNetwork's tweet image. CAR T-Cell therapy targeting #GPRC5D was found to be safe and effective for the treatment of relapsed/refractory #MM, according to a recent systematic meta-analysis. Learn more: hubs.ly/Q03mdDcN0

Featured today by @MSKLibrary: Phase I Trial of MCARH109, a G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D)-Targeted Chimeric Antigen Receptor T-Cell Therapy for Multiple Myeloma: An Updated Analysis #CAR_TCellTherapy #MultipleMyeloma #GPRC5D #CancerResearch

MSKLibrary's tweet image. Featured today by @MSKLibrary: Phase I Trial of MCARH109, a G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D)-Targeted Chimeric Antigen Receptor T-Cell Therapy for Multiple Myeloma: An Updated Analysis

#CAR_TCellTherapy #MultipleMyeloma #GPRC5D #CancerResearch

Although it was also cool the analogy of #GPRC5D bispecific followed by CAR-T against #BCMA as el chicharito in the Mexico vs Croatia game ⚽

#BeyondBlood in CDMX: Según @Rfonsi1, tratar el mieloma en los mayores es como ir a pescar 🎣 Such a cool analogy! Need to maintain line tension just right to catch #MMsm fish in ASCT-ineligible pts - if too much dex or too little dara, you may not achieve the best outcomes!

RahulBanerjeeMD's tweet image. #BeyondBlood in CDMX:
Según @Rfonsi1, tratar el mieloma en los mayores es como ir a pescar 🎣

Such a cool analogy!
Need to maintain line tension just right to catch #MMsm fish in ASCT-ineligible pts - if too much dex or too little dara, you may not achieve the best outcomes!


#GPRC5D AbbVie pens $1B deal for Simcere’s phase 1 T-cell engager. The candidate, SIM0500, is a humanized trispecific antibody that targets GPRC5D, BCMA, and CD3.Learn about our catalog: en.genomeditech.com

Genomeditech's tweet image. #GPRC5D AbbVie pens $1B deal for Simcere’s phase 1 T-cell engager. The candidate, SIM0500, is a humanized trispecific antibody that targets GPRC5D, BCMA, and CD3.Learn about our catalog: en.genomeditech.com

No results for "#gprc5d"

⚡️ La thérapie #CAR_Tcell 🩸 ciblée par l'antigène #GPRC5D induit une forte réponse dans le #MyélomeMultiple 👉#MCARH109, ​​une thérapie #CAR_T 🩸 ciblant l'antigène GPRC5D, a généré des rémissions chez 70,6 % des patients atteints de #Myélome multiple R/R www2.onclive.com/view/gprc5d-an…

jyves94's tweet image. ⚡️ La thérapie #CAR_Tcell 🩸 ciblée par l'antigène #GPRC5D induit une forte réponse dans le #MyélomeMultiple
👉#MCARH109, ​​une thérapie #CAR_T 🩸 ciblant l'antigène GPRC5D, a généré des rémissions chez 70,6 % des patients atteints de #Myélome multiple R/R
www2.onclive.com/view/gprc5d-an…

1-2> Matching modality to mechanism. The title above is something I've often commented on on Twitter, so it was nice to see. For example, #BMS has seen #GPRC5D as a more appropriate modality for cell therapy than bispecific antibodies, though I don't know the specific reasons.

onco_park's tweet image. 1-2> Matching modality to mechanism.
The title above is something I've often commented on on Twitter, so it was nice to see. For example, #BMS has seen #GPRC5D as a more appropriate modality for cell therapy than bispecific antibodies, though I don't know the specific reasons.

🩸 Le #CAR_T ciblé par #GPRC5D est prometteur dans le #MyélomeMultiple fortement prétraité. 👉 Sur les 17 patients traités, 12 patients ont obtenu une réponse, dont 6 ont obtenu une réponse complète. #MCARH109 #BCMA #CAR_Tcell #Myélome 🩸 cgtlive.com/view/gprc5d-ta…

jyves94's tweet image. 🩸 Le #CAR_T ciblé par #GPRC5D est prometteur dans le #MyélomeMultiple fortement prétraité.
👉 Sur les 17 patients traités, 12 patients ont obtenu une réponse, dont 6 ont obtenu une réponse complète.
#MCARH109 #BCMA #CAR_Tcell #Myélome 🩸
cgtlive.com/view/gprc5d-ta…

Bristol Myers Squibb $BMY Announces First Disclosures and New Data at #ASH22, Demonstrating Commitment to Raising Standards in Treatment Through Broad Multiple Myeloma Portfolio #GPRC5D CAR-T / Abecma / #BCMA TCE alnuctamab / #cellmods businesswire.com/news/home/2022…

BertrandBio's tweet image. Bristol Myers Squibb $BMY Announces First Disclosures and New Data at #ASH22, Demonstrating Commitment to Raising Standards in Treatment Through Broad Multiple Myeloma Portfolio #GPRC5D CAR-T / Abecma / #BCMA TCE alnuctamab / #cellmods businesswire.com/news/home/2022…
BertrandBio's tweet image. Bristol Myers Squibb $BMY Announces First Disclosures and New Data at #ASH22, Demonstrating Commitment to Raising Standards in Treatment Through Broad Multiple Myeloma Portfolio #GPRC5D CAR-T / Abecma / #BCMA TCE alnuctamab / #cellmods businesswire.com/news/home/2022…
BertrandBio's tweet image. Bristol Myers Squibb $BMY Announces First Disclosures and New Data at #ASH22, Demonstrating Commitment to Raising Standards in Treatment Through Broad Multiple Myeloma Portfolio #GPRC5D CAR-T / Abecma / #BCMA TCE alnuctamab / #cellmods businesswire.com/news/home/2022…
BertrandBio's tweet image. Bristol Myers Squibb $BMY Announces First Disclosures and New Data at #ASH22, Demonstrating Commitment to Raising Standards in Treatment Through Broad Multiple Myeloma Portfolio #GPRC5D CAR-T / Abecma / #BCMA TCE alnuctamab / #cellmods businesswire.com/news/home/2022…

BMS-986393 (#GPRC5D CAR-T). We will need to look at the adverse event profile by dose. ash.confex.com/ash/2023/webpr…

onco_park's tweet image. BMS-986393 (#GPRC5D CAR-T).
We will need to look at the adverse event profile by dose.
ash.confex.com/ash/2023/webpr…
onco_park's tweet image. BMS-986393 (#GPRC5D CAR-T).
We will need to look at the adverse event profile by dose.
ash.confex.com/ash/2023/webpr…

🩸 L'essai de la thérapie #CAR_TCell ciblant le #GPRC5D montre son efficacité dans le #MyélomeMultiple résistant R/R, & révèle des #Rémissions chez 70,6 % des patients inscrits. 👉 Le #CAR_T a produit des résultats impressionnants ! #CARTCR #ImmunoTherapy buff.ly/3MdehGe

jyves94's tweet image. 🩸 L'essai de la thérapie #CAR_TCell ciblant le #GPRC5D montre son efficacité dans le #MyélomeMultiple résistant R/R, & révèle des #Rémissions chez 70,6 % des patients inscrits.
👉 Le #CAR_T a produit des résultats impressionnants !
#CARTCR #ImmunoTherapy
buff.ly/3MdehGe

⚡️#TheLancet 👉Cellules #CAR_T #GPRC5D (#OriCAR_017) chez des patients atteints d’un #MyélomeMultiple #POLARIS en R/R, 1er essai de #Phase1 chez l’homme 👉La thérapie par #CAR_T ciblant #BCMA a montré une activité dans le traitement du #MyélomeMultiple R/R thelancet.com/journals/lanha…

jyves94's tweet image. ⚡️#TheLancet
👉Cellules #CAR_T #GPRC5D (#OriCAR_017) chez des patients atteints d’un #MyélomeMultiple #POLARIS en R/R, 1er essai de #Phase1 chez l’homme
👉La thérapie par #CAR_T ciblant #BCMA a montré une activité dans le traitement du #MyélomeMultiple R/R
thelancet.com/journals/lanha…

#MultipleMyeloma Studying the mechanisms of resistance to #Talquetamab: Based on a small patient sample, this study showed two mechanisms of resistance induced by the inability of talquetamab to bind to #GPRC5D. While resistance to GPRC5D by 1) genetic mutation is familiar,

onco_park's tweet image. #MultipleMyeloma 
Studying the mechanisms of resistance to #Talquetamab:
Based on a small patient sample, this study showed two mechanisms of resistance induced by the inability of talquetamab to bind to #GPRC5D. 

While resistance to GPRC5D by 1) genetic mutation is familiar,

🩸 L'essai de #Phase1 #POLARIS ciblées par #GPRC5D a montré un taux de réponse global de 100 % pour #OriCAR_017, une nouvelle thérapie #CAR_Tcell avec une nouvelle cible dans le #MyélomeMultiple R/R. targetedonc.com/view/gprc5d-ta…

jyves94's tweet image. 🩸 L'essai de #Phase1 #POLARIS ciblées par #GPRC5D a montré un taux de réponse global de 100 % pour #OriCAR_017, une nouvelle thérapie #CAR_Tcell avec une nouvelle cible dans le #MyélomeMultiple R/R.
targetedonc.com/view/gprc5d-ta…

Johnson & Johnson cherche à obtenir l'approbation de la #FDA pour un médicament contre le #MyélomeMultiple qui pourrait devenir le 1er à cibler une cible appelée #GPRC5D Les données de l'étude soutenant la demande de licence ont été présentées à l'#ASH22 medcitynews.com/2022/12/jj-aim…

jyves94's tweet image. Johnson & Johnson cherche à obtenir l'approbation de la #FDA pour un médicament contre le #MyélomeMultiple qui pourrait devenir le 1er à cibler une cible appelée #GPRC5D
Les données de l'étude soutenant la demande de licence ont été présentées à l'#ASH22 
medcitynews.com/2022/12/jj-aim…

🩸 Le #Talquetamab est un anticorps bispécifique expérimental, prêt à l'emploi, qui redirige les lymphocytes T ciblant à la fois le #GPRC5D, une nouvelle cible médicamenteuse, sur les cellules de #Myélome_Multiple et le #CD3 sur les #LymphocytesT.

jyves94's tweet image. 🩸 Le #Talquetamab est un anticorps bispécifique expérimental, prêt à l'emploi, qui redirige les lymphocytes T ciblant à la fois le #GPRC5D, une nouvelle cible médicamenteuse, sur les cellules de #Myélome_Multiple et le #CD3 sur les #LymphocytesT.

SpotlightReview: administration, safety, tolerability and toxicities of #Talquetamab a new bispecific antibody targeting #GPRC5D and #CD3 for the treatment of relapsed or #refractoryMultipleMyeloma. haematologica.org/article/view/h…

Haematologica's tweet image. SpotlightReview:  administration, safety, tolerability and toxicities of #Talquetamab a new bispecific antibody targeting #GPRC5D and #CD3 for the treatment of relapsed or #refractoryMultipleMyeloma.
haematologica.org/article/view/h…

Thérapie par #CAR_T 🧬 ciblée par #GPRC5D (#CT071) pour le #MyélomeMultiple 🩸 R/R : 1er essai de phase 1 chez l’homme. Le taux de réponse est de 100 % (IC à 95 % : 83,2-100), avec une réponse complète ou un taux supérieur de 50 % (dix patients sur 20). thelancet.com/journals/lanha…

jyves94's tweet image. Thérapie par #CAR_T 🧬 ciblée par #GPRC5D (#CT071) pour le #MyélomeMultiple 🩸 R/R : 1er essai de phase 1 chez l’homme.
Le taux de réponse est de 100 % (IC à 95 % : 83,2-100), avec une réponse complète ou un taux supérieur de 50 % (dix patients sur 20).
thelancet.com/journals/lanha…

Syed Maaz Tariq, MD, shares results from a retrospective analysis showing non-BCMA CAR T-Cell therapies, such as #GPRC5D, demonstrate efficacy and safety for patients with relapsed/refractory #MM. Learn more: hubs.ly/Q03tTTZk0

OncLearnNetwork's tweet image. Syed Maaz Tariq, MD, shares results from a retrospective analysis showing non-BCMA CAR T-Cell therapies, such as #GPRC5D, demonstrate efficacy and safety for patients with relapsed/refractory #MM. Learn more: hubs.ly/Q03tTTZk0

Retrouvez dans notre rubrique Myélome, l’analyse commentée rédigée par Sarah CAYLA sur l’article de Chari A, et al. N Engl J Med 2022 ➡️ tribunek-hemato.fr #myélome #Talquetamab #GPRC5D

TribuneK_Hemato's tweet image. Retrouvez dans notre rubrique Myélome, l’analyse commentée rédigée par Sarah CAYLA sur l’article de Chari A, et al. N Engl J Med 2022 ➡️ tribunek-hemato.fr
#myélome #Talquetamab #GPRC5D

Although the #GPRC5D gene is typically expressed in hair follicles, CD138-positive multiple myeloma cells have also been found to express GPRC5D. Learn more about the GPRC5D gene in its #BiologicalPathwayReview! hmpgloballearningnetwork.com/site/onc/biolo…

OncLearnNetwork's tweet image. Although the #GPRC5D gene is typically expressed in hair follicles, CD138-positive multiple myeloma cells have also been found to express GPRC5D. Learn more about the GPRC5D gene in its #BiologicalPathwayReview! hmpgloballearningnetwork.com/site/onc/biolo…

1> Relapse and Antigen Loss: Of the patients who responded, six relapsed after 3 to 9 months. These patients showed a decrease or complete loss of #GPRC5D protein expression. Ref: abit.ly/u1vbnc

onco_park's tweet image. 1> Relapse and Antigen Loss: 
Of the patients who responded, six relapsed after 3 to 9 months. These patients showed a decrease or complete loss of #GPRC5D protein expression.
Ref: abit.ly/u1vbnc

Great work by Sham Mailankody, ⁦@ESmithMDPhD⁩, and team on #GPRC5D #CART in #myeloma #mmsm

docbraunstein's tweet image. Great work by Sham Mailankody, ⁦@ESmithMDPhD⁩, and team on #GPRC5D #CART in #myeloma #mmsm

LucidQuest Updates > Hematology Today: CAR-T, Gene Therapy and Radioconjugates (Oct 6–13, 2025) dlvr.it/TNfK9P #BioPharmaandTechNews #HematologyNews #GPRC5D Comment below!

_timos_'s tweet image. LucidQuest Updates > Hematology Today: CAR-T, Gene Therapy and Radioconjugates (Oct 6–13, 2025) dlvr.it/TNfK9P #BioPharmaandTechNews #HematologyNews #GPRC5D Comment below!

CAR T-Cell therapy targeting #GPRC5D was found to be safe and effective for the treatment of relapsed/refractory #MM, according to a recent systematic meta-analysis. Learn more: hubs.ly/Q03mdDcN0

OncLearnNetwork's tweet image. CAR T-Cell therapy targeting #GPRC5D was found to be safe and effective for the treatment of relapsed/refractory #MM, according to a recent systematic meta-analysis. Learn more: hubs.ly/Q03mdDcN0

Loading...

Something went wrong.


Something went wrong.