#minimap2 search results

5 cm x 9 cm @nvidia Jetson TX2 SoC calling methylation on @nanopore NA12878 reads at 1.2Gbases/hour, powered by #minimap2 - split indexes and #Nanopolish - GPU accelerated signal alignment. 1 module for 1 PromethION module @martinalexsmith :D?

Hasindu2008's tweet image. 5 cm x 9 cm @nvidia Jetson TX2 SoC calling methylation on @nanopore NA12878 reads at 1.2Gbases/hour, powered by #minimap2 - split indexes and #Nanopolish - GPU accelerated signal alignment.
1 module for 1 PromethION module @martinalexsmith :D?

We are happy to announce F5N, the first ever mobile @nanopore sequence analyser available on Google Play play.google.com/store/apps/det… F5N includes #minimap2, #samtools & #f5c @Hasindu2008 (improved #nanopolish). Please test F5N & report issues @ github.com/SanojPunchihew…

hiruna72's tweet image. We are happy to announce F5N, the first ever mobile @nanopore sequence analyser available on Google Play play.google.com/store/apps/det… F5N includes #minimap2, #samtools & #f5c @Hasindu2008 (improved #nanopolish). Please test F5N & report issues @ github.com/SanojPunchihew…

Pre-release of mm2-fast - our accelerated version of minimap2 - is out! Compatible with minimap2 v2.22. Working on another release that would be compatible with latest minimap2 version (v2.24). #genomics #longreads #Minimap2 #HPC @Saurabh_Kalikar @chirgjain @wasim_galaxy @lh3lh3

sanchit_misra's tweet image. Pre-release of mm2-fast - our accelerated version of minimap2 - is out! Compatible with minimap2 v2.22. Working on another release that would be compatible with latest minimap2 version (v2.24). #genomics #longreads #Minimap2 #HPC @Saurabh_Kalikar @chirgjain @wasim_galaxy @lh3lh3

The @ncbi Eukaryotic Annotation Pipeline has switched it's aligner from splign to #minimap2 #PAGXXVIII @lh3lh3 @nanopore @PacBio @illumina

DCGenomics's tweet image. The @ncbi Eukaryotic Annotation Pipeline has switched it's aligner from splign to #minimap2 #PAGXXVIII @lh3lh3 @nanopore @PacBio @illumina

Now our #Rock64 cluster with #ARM processors can "reliably" perform #minimap2 + #nanopolish call-methylation for 8 Gbase minION flow cell data in around 6.5 hours. Now the PromethION time. @martinalexsmith @Psy_Fer_ the NAS is now doing good !!

Hasindu2008's tweet image. Now our #Rock64 cluster with #ARM processors can "reliably" perform #minimap2 + #nanopolish call-methylation for  8 Gbase minION flow cell data in around 6.5 hours. Now the PromethION time.
@martinalexsmith @Psy_Fer_ the NAS is now doing good !!
Hasindu2008's tweet image. Now our #Rock64 cluster with #ARM processors can "reliably" perform #minimap2 + #nanopolish call-methylation for  8 Gbase minION flow cell data in around 6.5 hours. Now the PromethION time.
@martinalexsmith @Psy_Fer_ the NAS is now doing good !!
Hasindu2008's tweet image. Now our #Rock64 cluster with #ARM processors can "reliably" perform #minimap2 + #nanopolish call-methylation for  8 Gbase minION flow cell data in around 6.5 hours. Now the PromethION time.
@martinalexsmith @Psy_Fer_ the NAS is now doing good !!

latest test subject: @nvidia JetsonNano, performing #minimap2(CPU only -4 hg38 index parts) at 174.1 Kb/s and #f5c (GPU #nanopolish call-methylation) at 326.9Kb/s. Adequate to keep up methylation calling with the @nanopore MinIT's 150kb/s base-calling rate and thus the MinION

Hasindu2008's tweet image. latest test subject: @nvidia JetsonNano, performing #minimap2(CPU only -4 hg38 index parts) at 174.1 Kb/s and #f5c (GPU #nanopolish call-methylation) at 326.9Kb/s. Adequate to keep up methylation calling with the @nanopore MinIT's 150kb/s base-calling rate and thus the MinION

This is amazing. #Minimap2 was published less than three months ago and already had 68 citations. I’m looking to add another. Well done Heng Li (@lh3lh3). I look forward to meeting you someday. academic.oup.com/bioinformatics…

bioinfo_mark's tweet image. This is amazing. #Minimap2 was published less than three months ago and already had 68 citations. I’m looking to add another. 

Well done Heng Li (@lh3lh3). I look forward to meeting you someday. 

academic.oup.com/bioinformatics…

Fun fact: Meanwhile, the #ARM cluster performs methylation calling on 75Gb in 15h (5.2h of I/O |14.8h compute). Server ~60h fast5 I/O, ~3h compute on 60Gb. #minimap2 ~2h on the server (peak RSS 20GB) and ~16h on #ARM cluster (peak RSS <4GB)

Hasindu2008's tweet image. Fun fact: Meanwhile, the #ARM cluster performs methylation calling on 75Gb in 15h (5.2h of I/O |14.8h compute). Server ~60h fast5 I/O, ~3h compute on 60Gb.
#minimap2 ~2h on the server (peak RSS 20GB) and ~16h on #ARM cluster (peak RSS &amp;lt;4GB)

Calling methylation for a 60 Gbase Promethion dataset on a 72 thread server with HD RAID. fast5 load time: 62.72 h - open time: 41.08 h - read time: 19.31 h data processing time: 2.92 h Is anyone aware of a good workaround for fast HDF5 file access?



Excited to share a blog summarizing our work on mm2-fast - our accelerated version of minimap2 that is up to 1.8x faster: bwa-mem2.github.io/mm2-fast-blog-…. This work also got published at "Nature Computational Science" earlier this year. Code availability github.com/bwa-mem2/mm2-f… #Minimap2


I am thrilled to present mm2-fast: an accelerated version of Minimap2 that achieves up to 3.5x speedup on CPUs while maintaining identical output. Code: github.com/lh3/minimap2/t… #genomics #longreads #Minimap2 #HPC @Saurabh_Kalikar @chirgjain @wasim_galaxy @lh3lh3

Accelerating long-read analysis on modern CPUs biorxiv.org/cgi/content/sh… #bioRxiv



New update to the #minimap2 #rust crate. Experimental multithread support. crates.io/crates/minimap2


#Minimap2 library for #Python: pypi.org/project/minima… Very alpha stage, but has multithreading. Results are returned in DataFrames with @DataPolars (easy convert to Pandas). Feedback appreciated. I don't know what platforms it'll work on. #Bioinformatics #Genomics #Nanopore


minimap2-fpga: Integrating hardware-accelerated chaining for efficient end-to-end long-read sequence mapping. #Minimap2 #FPGA #Bioinformatics @biorxivpreprint biorxiv.org/content/10.110…


@erikgarrison Another way to wrap #minimap2.

ViralMSA: Massively scalable reference-guided multiple sequence alignment of viral genomes biorxiv.org/cgi/content/sh… #biorxiv_bioinfo



after 2008, a lot is changing again, i am looking at reads spanning entire transcripts with @nanopore and #minimap2 aligner, amazing


If you are analysing data from an organism/condition for which there is already a high quality reference annotation, providing splice junctions during alignment (e.g. with #minimap2) is much better than post-alignment correction techniques.


#minimap2 is great ! dozens of times faster than lastal !


Inspired by the -x presets in #minimap2, we are introducing presets to #f5c for maximising performance on a variety of systems, e.g. -x laptop, -x hpc, etc. [see f5c.page.link/profiles] If specific presets for your system is needed, let us know.


Check out our latest publication at nature.com/articles/s4159… - A method to align long read sequences accurately on devices with even 2GB of RAM - powered by a partitioned index + post merging technique attached to #minimap2.

Our work with @Hasindu2008 and Prof Sri Parameswaran from @UNSWCOMPUTING out in @SciReports



📋Explore one of the highlights of long-read sequence alignment in #OmicsBox 3.1 biobam.com/long-read-sequ… Learn about the complexities of using #Minimap2 for #longreads and #RNA sequence alignment, its features, benefits, and practical applications! #Bioinformatics #Genomics

bio_bam's tweet image. 📋Explore one of the highlights of long-read sequence alignment in #OmicsBox 3.1

biobam.com/long-read-sequ…

Learn about the complexities of using #Minimap2 for #longreads and #RNA sequence alignment, its features, benefits, and practical applications! 

#Bioinformatics  #Genomics

minimap2-fpga: Integrating hardware-accelerated chaining for efficient end-to-end long-read sequence mapping. #Minimap2 #FPGA #Bioinformatics @biorxivpreprint biorxiv.org/content/10.110…


#Minimap2 #Rust library update. Updates to 2.26, with_seq function, hopeful for MacOS/aarch64 compilation. See full announcement here: sci.kiwi/@josephguhlin/… Crate is here: crates.io/crates/minimap2 #bioinformatics #genomics #nanopore #pacbio


#Minimap2 library for #Python: pypi.org/project/minima… Very alpha stage, but has multithreading. Results are returned in DataFrames with @DataPolars (easy convert to Pandas). Feedback appreciated. I don't know what platforms it'll work on. #Bioinformatics #Genomics #Nanopore


New update to the #minimap2 #rust crate. Experimental multithread support. crates.io/crates/minimap2


mm2-fast: accelerated version of minimap2 that is up to 1.8x faster. #minimap2 #Genomics #longreads #HPC #iamintel @lh3lh3 @chirgjain @wasim_galaxy @Saurabh_Kalikar

Excited to share a blog summarizing our work on mm2-fast - our accelerated version of minimap2 that is up to 1.8x faster: bwa-mem2.github.io/mm2-fast-blog-…. This work also got published at "Nature Computational Science" earlier this year. Code availability github.com/bwa-mem2/mm2-f… #Minimap2



Excited to share a blog summarizing our work on mm2-fast - our accelerated version of minimap2 that is up to 1.8x faster: bwa-mem2.github.io/mm2-fast-blog-…. This work also got published at "Nature Computational Science" earlier this year. Code availability github.com/bwa-mem2/mm2-f… #Minimap2


Pre-release of mm2-fast - our accelerated version of minimap2 - is out! Compatible with minimap2 v2.22. Working on another release that would be compatible with latest minimap2 version (v2.24). #genomics #longreads #Minimap2 #HPC @Saurabh_Kalikar @chirgjain @wasim_galaxy @lh3lh3

sanchit_misra's tweet image. Pre-release of mm2-fast - our accelerated version of minimap2 - is out! Compatible with minimap2 v2.22. Working on another release that would be compatible with latest minimap2 version (v2.24). #genomics #longreads #Minimap2 #HPC @Saurabh_Kalikar @chirgjain @wasim_galaxy @lh3lh3

Thanks for the suggestion! Ours are 151bp PE reads, looks like #minimap2 would work (and 3x time faster)! We will def try it - would be nice to benchmark minimap2vsbwamem on WGS somatic calls since we are receiving more WGS projects! :) #bioinformatics


I am thrilled to present mm2-fast: an accelerated version of Minimap2 that achieves up to 3.5x speedup on CPUs while maintaining identical output. Code: github.com/lh3/minimap2/t… #genomics #longreads #Minimap2 #HPC @Saurabh_Kalikar @chirgjain @wasim_galaxy @lh3lh3

Accelerating long-read analysis on modern CPUs biorxiv.org/cgi/content/sh… #bioRxiv



Anyone knows the answer to this? #minimap2 #longread #aligner "Does option --secondary=no equal to -N 1" biostars.org/p/9480592


If you are analysing data from an organism/condition for which there is already a high quality reference annotation, providing splice junctions during alignment (e.g. with #minimap2) is much better than post-alignment correction techniques.


We are happy to announce F5N, the first ever mobile @nanopore sequence analyser available on Google Play play.google.com/store/apps/det… F5N includes #minimap2, #samtools & #f5c @Hasindu2008 (improved #nanopolish). Please test F5N & report issues @ github.com/SanojPunchihew…

hiruna72's tweet image. We are happy to announce F5N, the first ever mobile @nanopore sequence analyser available on Google Play play.google.com/store/apps/det… F5N includes #minimap2, #samtools &amp;amp; #f5c @Hasindu2008 (improved #nanopolish). Please test F5N &amp;amp; report issues @ github.com/SanojPunchihew…

5 cm x 9 cm @nvidia Jetson TX2 SoC calling methylation on @nanopore NA12878 reads at 1.2Gbases/hour, powered by #minimap2 - split indexes and #Nanopolish - GPU accelerated signal alignment. 1 module for 1 PromethION module @martinalexsmith :D?

Hasindu2008's tweet image. 5 cm x 9 cm @nvidia Jetson TX2 SoC calling methylation on @nanopore NA12878 reads at 1.2Gbases/hour, powered by #minimap2 - split indexes and #Nanopolish - GPU accelerated signal alignment.
1 module for 1 PromethION module @martinalexsmith :D?

Pre-release of mm2-fast - our accelerated version of minimap2 - is out! Compatible with minimap2 v2.22. Working on another release that would be compatible with latest minimap2 version (v2.24). #genomics #longreads #Minimap2 #HPC @Saurabh_Kalikar @chirgjain @wasim_galaxy @lh3lh3

sanchit_misra's tweet image. Pre-release of mm2-fast - our accelerated version of minimap2 - is out! Compatible with minimap2 v2.22. Working on another release that would be compatible with latest minimap2 version (v2.24). #genomics #longreads #Minimap2 #HPC @Saurabh_Kalikar @chirgjain @wasim_galaxy @lh3lh3

Now our #Rock64 cluster with #ARM processors can "reliably" perform #minimap2 + #nanopolish call-methylation for 8 Gbase minION flow cell data in around 6.5 hours. Now the PromethION time. @martinalexsmith @Psy_Fer_ the NAS is now doing good !!

Hasindu2008's tweet image. Now our #Rock64 cluster with #ARM processors can &quot;reliably&quot; perform #minimap2 + #nanopolish call-methylation for  8 Gbase minION flow cell data in around 6.5 hours. Now the PromethION time.
@martinalexsmith @Psy_Fer_ the NAS is now doing good !!
Hasindu2008's tweet image. Now our #Rock64 cluster with #ARM processors can &quot;reliably&quot; perform #minimap2 + #nanopolish call-methylation for  8 Gbase minION flow cell data in around 6.5 hours. Now the PromethION time.
@martinalexsmith @Psy_Fer_ the NAS is now doing good !!
Hasindu2008's tweet image. Now our #Rock64 cluster with #ARM processors can &quot;reliably&quot; perform #minimap2 + #nanopolish call-methylation for  8 Gbase minION flow cell data in around 6.5 hours. Now the PromethION time.
@martinalexsmith @Psy_Fer_ the NAS is now doing good !!

The @ncbi Eukaryotic Annotation Pipeline has switched it's aligner from splign to #minimap2 #PAGXXVIII @lh3lh3 @nanopore @PacBio @illumina

DCGenomics's tweet image. The @ncbi Eukaryotic Annotation Pipeline has switched it&apos;s aligner from splign to #minimap2 #PAGXXVIII @lh3lh3 @nanopore @PacBio @illumina

latest test subject: @nvidia JetsonNano, performing #minimap2(CPU only -4 hg38 index parts) at 174.1 Kb/s and #f5c (GPU #nanopolish call-methylation) at 326.9Kb/s. Adequate to keep up methylation calling with the @nanopore MinIT's 150kb/s base-calling rate and thus the MinION

Hasindu2008's tweet image. latest test subject: @nvidia JetsonNano, performing #minimap2(CPU only -4 hg38 index parts) at 174.1 Kb/s and #f5c (GPU #nanopolish call-methylation) at 326.9Kb/s. Adequate to keep up methylation calling with the @nanopore MinIT&apos;s 150kb/s base-calling rate and thus the MinION

Fun fact: Meanwhile, the #ARM cluster performs methylation calling on 75Gb in 15h (5.2h of I/O |14.8h compute). Server ~60h fast5 I/O, ~3h compute on 60Gb. #minimap2 ~2h on the server (peak RSS 20GB) and ~16h on #ARM cluster (peak RSS <4GB)

Hasindu2008's tweet image. Fun fact: Meanwhile, the #ARM cluster performs methylation calling on 75Gb in 15h (5.2h of I/O |14.8h compute). Server ~60h fast5 I/O, ~3h compute on 60Gb.
#minimap2 ~2h on the server (peak RSS 20GB) and ~16h on #ARM cluster (peak RSS &amp;lt;4GB)

Calling methylation for a 60 Gbase Promethion dataset on a 72 thread server with HD RAID. fast5 load time: 62.72 h - open time: 41.08 h - read time: 19.31 h data processing time: 2.92 h Is anyone aware of a good workaround for fast HDF5 file access?



This is amazing. #Minimap2 was published less than three months ago and already had 68 citations. I’m looking to add another. Well done Heng Li (@lh3lh3). I look forward to meeting you someday. academic.oup.com/bioinformatics…

bioinfo_mark's tweet image. This is amazing. #Minimap2 was published less than three months ago and already had 68 citations. I’m looking to add another. 

Well done Heng Li (@lh3lh3). I look forward to meeting you someday. 

academic.oup.com/bioinformatics…

📋Explore one of the highlights of long-read sequence alignment in #OmicsBox 3.1 biobam.com/long-read-sequ… Learn about the complexities of using #Minimap2 for #longreads and #RNA sequence alignment, its features, benefits, and practical applications! #Bioinformatics #Genomics

bio_bam's tweet image. 📋Explore one of the highlights of long-read sequence alignment in #OmicsBox 3.1

biobam.com/long-read-sequ…

Learn about the complexities of using #Minimap2 for #longreads and #RNA sequence alignment, its features, benefits, and practical applications! 

#Bioinformatics  #Genomics

#nanopores @Hasindu2008: 'latest test subject: @nvidia JetsonNano, performing #minimap2(CPU only -4 hg38 index parts) at 174.1 Kb/s and #f5c (GPU #nanopolish call-methylation) at 326.9Kb/s. Adequate to keep up methylati… https://t.co/o49Yuf3QRF, see more tweetedtimes.com/v/176?s=tnp

SeqComplete's tweet image. #nanopores @Hasindu2008: &apos;latest test subject: @nvidia JetsonNano, performing #minimap2(CPU only -4 hg38 index parts) at 174.1 Kb/s and #f5c (GPU #nanopolish call-methylation) at 326.9Kb/s. Adequate to keep up methylati… https://t.co/o49Yuf3QRF, see more tweetedtimes.com/v/176?s=tnp

#nanopores @Hasindu2008: '5 cm x 9 cm @nvidia Jetson TX2 SoC calling methylation on @nanopore NA12878 reads at 1.2Gbases/hour, powered by #minimap2 - split indexes and #Nanopolish - GPU accelerated signal alignment. 1 m… https://t.co/QOm8RByagu, see more tweetedtimes.com/v/176?s=tnp

SeqComplete's tweet image. #nanopores @Hasindu2008: &apos;5 cm x 9 cm @nvidia Jetson TX2 SoC calling methylation on @nanopore NA12878 reads at 1.2Gbases/hour, powered by #minimap2 - split indexes and #Nanopolish - GPU accelerated signal alignment.
1 m… https://t.co/QOm8RByagu, see more tweetedtimes.com/v/176?s=tnp

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