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⚛️ When Ir meets boranes, chemistry hits different! Now in @J_A_C_S: Our Ir-catalyzed allylation via intermolecular 1,4-boronate rearrangement enables enantioselective access to (R)-pyricuol in 2 steps. 🎉 Congrats Team! 🔗 [pubs.acs.org/doi/10.1021/ja…] @BristolChem @bobbypaton
🎉 Huge congratulations to Dr. Malcolm George on successfully defending his PhD thesis! He’s now joining Pharmaron as a Senior Scientist in Process Chemistry. Wishing him every success in this exciting new chapter! 👏
💍 Looking for a ring? try one with Bpins! Check out our intramolecular lithiation–borylation route to 1,3-bis-boronic ester carbocycles, now out in @angew_chem. Congrats Chris and team! 🔗onlinelibrary.wiley.com/doi/10.1002/an… In collaboration with @merckgroup. #Organoborons @bristolchem
🌊 From a marine sponge to @angew_chem Novit! Mycapolyol E: fully synthesized and structurally confirmed via boronic ester homologation. 20 steps (LLS). 12 stereocenters. Congrats @sheenagh_aiken, @DylanRigby6 & team! 🔗 dx.doi.org/10.1002/anov.7… @BristolChem #TotalSynthesis
Radicals, tamed! Our new @J_A_C_S paper reveals an in situ doublet-state photocatalyst rivaling top photoreductants—enabling borylations & more. Huge congrats to the team! 🎉 #photocatalysis @BristolChem pubs.acs.org/doi/10.1021/ja…
Congratulations to Hannah on successfully defending her thesis! She is now Dr. Han. Wishing her all the best!
After his postdoctoral stay @GloriusGroup, we warmly welcome Dr. Jasper Tyler back to the group—this time as our Research Officer. Looking forward to working with you, Jasper!
This week, we bid farewell to Gianluca, who worked with Hanwen, as he returns to @DellAmico_group at Università di Padova to complete his PhD. Wishing you all the success!
Bittersweet April as we said goodbye to group members: Javier returned to UAM to finish his PhD, Dr. Min Siauciulis has a new position in industry, and Dr. Zeshu Wang moved to @Schoenebeck_Lab. Wishing them all every success ahead!
Huge congrats to Dr. Adam Noble as he kicks off his independent career at Uni Bristol! Your incredible work at the Aggarwal Group has been invaluable. We’re so excited to see where this next chapter takes you!
Now online & open access: Article by Malcolm R. P. George, Craig P. Butts, Varinder K. Aggarwal & co-workers @AggarwalLab The combination of synthesis and ultra-high-resolution NMR spectroscopy reveals the correct structure of caylobolide A nature.com/articles/s4416…
Our latest work with the Butt's group, out now on @ChemEurope, enables the facile and quantitative stereochemical assignment of 1,5-diols in natural products. Congrats, Max and Malcolm! …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/ce… @BristolChem #naturalproducts #stereochem #NMR
Come and hear the latest from our star-studded speakers at this years BSM. Deadline for registration is 28th March. Please re-tweet.
Congratulations to Dylan on successfully defending his thesis! He is now Dr. Rigby. Wishing him all the best!
Interesting to discover that organozinc reagents react with inversion of configuration with pi-allyl iridum complexes, unlike other electrophiles where they react with retention. Congratulations to Hong Cheng for his meticulous studies. @J_A_C_S @BristolChem @AggarwalLab
Iridium-Catalyzed Stereocontrolled C(sp3)–C(sp3) Cross-Coupling of Boronic Esters and Allylic Carbonates Enabled by Boron-to-Zinc Transmetalation | Journal of the American Chemical Society @BristolUni @BristolChem @VarinderAggar11 @TotalSyntheses pubs.acs.org/doi/10.1021/ja…
Congratulations to Chris, who defended his thesis and is now Dr. Cope, and to Dr. Huaquan Fang for Finishing up your research stay at our group. All the best to both of you!
Our latest work, out now @J_A_C_S, merged organocatalysis (MBH) w/ 1,2-boronate rearrangement to access enantioenriched, highly substituted indole and indolines. Great work team!🥳 pubs.acs.org/doi/10.1021/ja… @BristolChem #organocatalysis #boronates #research
Our latest work, in collaboration with @bobbypaton, is out now @angew_chem. We developed a regio- and enantioselective Pt-catalyzed diboration of unactivated alkenes with (pin)B−B(dan), where B(dan) goes to the less hindered carbon. Congrats to team! onlinelibrary.wiley.com/doi/10.1002/an…
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