COSBID
@COSBID
Co-Operative Studies on Brain Injury Depolarizations (COSBID) is a research interest group focused on cortical spreading depolarizations #TBI #stroke #SAH #ICH
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When 100+ spreading depolarizations run through the temporal lobe of a brain injured human being, the question of treatment goes beyond academic musings. We need answers.
Prognostic Value of Spreading Depolarizations in Patients With Severe Traumatic Brain Injury ja.ma/35dl4J9
Today marks 75 years of spreading depression research! August 14, 1944, Leão's landmark paper was received for publication in @JNeurophysiol. It would take 58 years for Leão's work to be translated to the clinic, sparking a #SpreadingDepolarizations Renaissance! #TBI #stroke #SAH
Thanks to Drs. Suzuki and Oka for hosting another excellent COSBID meeting - the first in Asia - in Yokohama, Japan. Excellent discussions and science among a very thoughtful group. #spreadingdepolarizations
Monitoring infraslow waves of brain injury (#spreadingdepolarization) with graphene transistors - on the cover of Nature Materials!
Headed to #NTS2019 organized by @neurologyrules. Looking forward to seeing @cgzammit @MobergICU @SurgeonScience and many others! #neurocritical #ICU
If you haven't already, please be sure to register for this year's #COSBID2019 in Yokohama, Japan! cosbid.org/meeting/curren… or see icsd2019.jp for more information!
Very good visualizations of cortical spreading depolarizations #AANAM Radial, spiral and reverberating waves of spreading depolarization occ... sciencedirect.com/science/articl…
The Continuum of #spreadingdepolarizations is the SECOND most cited reference @_JCBFM of the last three years! Congrats to the @JedHartings and co-authors! journals.sagepub.com/home/jcb#674a3…
A case of amyloid angiopathy presenting with 15-20 min transient neuro symptoms (‘amyloid spells’) related to migraine-like #spreadingdepolarizations. Characteristic MRI and biopsy confirmed the diagnosis! @COSBID #AANAM
Fascinating work! #AANAM
Looking forward to presenting our work from @UofR @URNeuroscience on the role of the #glymphatic system in driving cerebral edema after acute ischemic stroke tomorrow at #AANAM @AANMember. Stop by room 118A at 3:50pm!
Frontiers in Neuroscience plenary with @JedHartings at #AANAM explaining the remarkable prevalence of #spreadingdepolarizations and its role in excitotoxicity after brain injury #NeuroCC #stroke #tbi @UCNeuroPMR @UCNeurosurgery @UCHealthNews @AANMember
Brain tsunamis in stroke highlighted in the Albuquerque Journal! #cosbid #spreadingdepolarization Battling the effects of cerebral tsunamis abqjournal.com/1301127 #abq via @abqjournal
Why isn't there a perfect animal model for aneurysmal subarachnoid hemorrhage? We wrote this article to try answering the question, and to start a conversation about what sorts of outcomes matter for translation to patients. rdcu.be/bsWKf link.springer.com/article/10.100…
Recording of Sharon Jewell's Spreading Depolarizations webinar now available. - mailchi.mp/2ca2ebc8bd92/p…
A technical guide to imaging cerebral blood flow in rodents @_JCBFM from David Kleinfeld's lab @UCSDNeuro @UCSDHealth @UCSDnews - Two-Photon Microscopy to Study Blood Flow and Neurovascular Coupling journals.sagepub.com/doi/pdf/10.103…
Friday March 1st join @MobergICU for a #BrainMatters webinar featuring Sharon Jewell with @KingsCollegeLon. See below for registration information! #spreadingdepolarizations
Just ONE WEEK until our next #BrainMatters webinar! Join us on March 1st at 1pm EST to learn more about spreading depolarizations in the injured brain with Sharon Jewell. Register here: zoom.us/webinar/regist…
Interesting study! Especially in light of recent work on cilostazol (also inihibits plt aggregation and promotes vasodilation via phosphodiesterase inhibiton). Wonder what the effects of terutroban are on #spreadingdepolarizations? #SAH
Thromboxane–prostaglandin receptor antagonist, terutroban, prevents neurovascular events after subarachnoid haemorrhage: a nanoSPECT study in rats #FOAMcc bit.ly/2SrYMSf
The first successful targeting of spreading depolarizations in patients with subarachnoid hemorrhage. Cilostazol decreases the sequela of SDs after SAH and demonstrates how SDs can affect outcome after #SAH. @COSBID onlinelibrary.wiley.com/doi/pdf/10.100…
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