CELL
@CellBioSF
CELL: Consortium for the Equations of Life and Living Systems. Fusing MathBio, BioPhysics, CompBio and DescriptiveBio around an aggressive mathematical core.
What is the universal mathematical configuration space in biology that we are building t CELL: Consortium for the Equations of Life and Living Systems and why do we need it? Physics got real when it chose Hilbert space as the home of states, fixed the operator algebra, and…
The 2025 medicine laureate Shimon Sakaguchi’s groundbreaking research transformed our understanding of how the immune system maintains balance. In the mid-1990s, Sakaguchi identified a unique subset of T cells that act as the immune system’s “brakes.” These regulatory T cells…
🚀🚀David Baker preprint is here!! What if we could test hundreds of designed proteins per day instead of waiting weeks for just a few dozen?@UW @biorxivpreprint "Accelerating protein design by scaling experimental characterization"(v2) • Recent advances in computational…
Nature Methods Squidiff: predicting cellular development and responses to perturbations using a diffusion model nature.com/articles/s4159…
We're excited to announce NOBLE (Neural Operator with Biologically Informed Latent Embeddings), accepted to @NeurIPSConf NOBLE is our new neural operator framework designed for neuroscience research, accurately predicting somatic voltage responses to current injections in…
Demis Hassabis and John Jumper, the 2024 Nobel Prize laureates in chemistry, have developed an AI model to solve a 50-year-old problem: predicting proteins’ complex structures. In 2020, Hassabis and Jumper presented an AI model called AlphaFold2. With its help, they have been…
I feel like crap. I didn’t get any grants this year, so I had to let go of my super talented postdoc—someone with a doctorate who’s now unemployed, without benefits or retirement, and still grinding away on a paper... Postdocs are the most unappreciated and undervalued positions…
But I am keen to update preprints continually even after the useless but mandatory journal publication with extensive case studies of successes & failures OR update the preprints to link to other studies (our or others) that show success & failure cases. 3/3
One of the things we have been actively aiming to improve in our science & publications is extensive analysis of failure modes of our own models AND exposing this honestly & exhaustively in our preprints. 1/
it’s an exciting time for mathematics (and science broadly)!
I firmly believe we are at a watershed moment in the history of mathematics. In the coming years, using LLMs for math research will become mainstream, and so will Lean formalization, made easier by LLMs. (1/4)
🚀 Interested in AI for living systems? Apply to the UCSD Schmidt AI in Science Postdoc Fellowship! We are exploring AI to uncover the Equations of Living Systems—from cell differentiation to tissue rheology (deadline Oct 6). Please share/reach out. 🔗 postdoc.ucsd.edu/funding/schmid…
Thrilled to share that I’ll be joining @UCLA as Professor in July 2026! Grateful to my amazing students, postdocs, colleagues @UCR, collaborators, and mentors. A new chapter begins, advancing #compchem, #AI to explore #RNA, #DNA, #CRISPR, and emerging directions in #Biophysics.
The UCLA Department of Chemistry & Biochemistry is excited to welcome world-renowned computational biophysicist Prof. Giulia Palermo @palermo_lab, who will join the @UCLA faculty as a Full Professor on July 1, 2026! chemistry.ucla.edu/news/welcoming…
🎈🌿 We are delighted to announce that The Living Physics Lab and Dr David Jordan, joins CELL: Consortium for the Equations of Life and Living Systems as a 'Founding Member Lab'. cellbiosf.substack.com/p/the-living-p… David is the Founding Director of the Living Physics Lab in Cambridge, UK,…
At CELL, we plan to structure the consortium around focused working groups and fast-moving swarms. Details are in the link below. Tell us where this model works, where it breaks, and how to improve it. Your feedback will directly shape the future of open science.…
What is the universal mathematical configuration space in biology that we are building t CELL: Consortium for the Equations of Life and Living Systems and why do we need it? Physics got real when it chose Hilbert space as the home of states, fixed the operator algebra, and…
Biological intuition seduces us with language like “gene expression space” or “metabolic state space,” but these are conceptual shadows. What lives in the notebooks of molecular biologists is not yet a space in the mathematical sense. The CELL initiative demands we be precise: a…
Can't wait to dig deep on this. Invariably I just love everything that comes out of Prof @AnimaAnandkumar lab and team! Will be writing soon on how this effort may port into what we are building at CELL /cc @CellBioSF
Physics-informed learning is essential for AI+Science. Check out our latest paper in @PNASNews special edition on AI+Chemistry on incorporating simple rules of physics that two atoms in a molecule cannot get too close to one another (due to repulsive forces) vastly improves…
Good point. My first paper was on time travel in the Gödel universe. ML was easy to pick up after that :) journals.aps.org/prd/abstract/1…
We’ve found a ton of value hiring folks with strong theory backgrounds with little to no production ML experience. One of our members of technical staff got his phd in pure math/the geometry of black holes and had no prior ML experience. Within days of hiring him we released our…
We’ve found a ton of value hiring folks with strong theory backgrounds with little to no production ML experience. One of our members of technical staff got his phd in pure math/the geometry of black holes and had no prior ML experience. Within days of hiring him we released our…
Absolutely the right take. People have wrongly complained about places like Harvard CS having “too much theory” forever. Turns out if you get the theory it’s not that hard to apply it. The reverse is not true. That + a culture of students working on side projects with their…
Prof. Chen Ning Yang, a world-renowned physicist, Nobel Laureate in Physics, Academician of the Chinese Academy of Sciences, Professor at Tsinghua University, and Honorary Director of the Institute for Advanced Study at Tsinghua University, passed away in Beijing due to illness…
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