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There should be a bug bounty-like scheme for finding these kind of things financed by the state. A drug bounty. If one proves through a clinical trial that a product is good or bad, then they get a certain amount of money proportional to amount of life gained
Resolve this longevity paradox for me: -"1 extra year of healthy lifespan is worth $37T!" -a clinical trial to study whether rapamycin (most reliable drug that extends lifespan in mice, is off patent) can reasonably slow aging costs ~ $80M. Nobody has done this yet.
It is even more insane than you think. Everyone there says it is not nearly enough
It's even more insane than you think - the median pensioner in France has higher income than the median working age adult
Regular reminder France already spends the largest share of national income on pensions in the whole Eurozone. It feels like the domestic debate on fiscal issues is so detached from reality, it is hard for an outsider to begin to comprehend.
A suggestion. A suspension of the retirement reform is a jump without a parachute. Given the widely different views (remember how it went last time), it means months if not years of haggling, during which the situation steadily deteriorates. Why not do the reverse? Construct…
20 ans de drama en une slide
En l'an 2000, notre école marche, notre hôpital est de qualité, les finances sont saines et la croissance est forte. En 2025, tout l'inverse. Qu'est-ce qui s'est passé ? On a dirigé toute notre dépense vers des virements (retraite, remboursements) plutôt que vers les services.
The Economist on firing people in the US versus Europe: There are two ways for Western companies to sack lots of people. The American one involves the boss inviting hundreds of unsuspecting employees on a Zoom call, offering them a few months’ wages as severance and insincerely…
whenever i visit paris I have whatever the opposite of Paris syndrome is. it was shocking to me that such a place could exist and not be the most important city in the world and not incessantly talked about
L'effet Laffer, ce n'est pas que le manque à gagner, c'est surtout la destruction de valeur. Le but d'une société doit être de prospérer. Enrichir l'état n'est pas un but en soi.
🇪🇺 VON DER LEYEN: “AI FIRST!”... AND ONE PERSON CLAPS European Commission President Ursula von der Leyen tried to rally Brussels around artificial intelligence - and got a single clap for her trouble. “AI first!” she declared at a recent event, before pausing… and hearing…
🇪🇺🇬🇱 EU THROWS CASH AT GREENLAND - AND SHADE AT TRUMP Ursula von der Leyen just promised to double EU funding for Greenland. Meaning: Europe’s making sure the Arctic island doesn’t drift into Washington or Beijing’s orbit. “Trusted and reliable partners,” she said - diplomatic…
But if the technology was perfect. You are better off doing a only a dozen cells and really high depth.. + many cells at low depth as each gives you different kind of data
It is not so much about depth vs number of cells but the technology one uses. Some like 10x V3 will quickly reach a plateau whereas other will continue discovering new UMIs.
Vous voulez que les dividendes ouvrent des droits à la retraite? Et lorsqu'ils s'arrêtent, l'Etat les remplace? Assurance chômage pour dividendes?
En France, le travail est plus taxé que le capital. 100 € de salaire → 54 € nets 100 € de dividendes → 70 € nets Si Lecornu veut vraiment du changement, c’est là qu’il doit agir : rééquilibrer les plateaux de la balance.
Today, @ekindogus and I are excited to introduce @periodiclabs. Our goal is to create an AI scientist. Science works by conjecturing how the world might be, running experiments, and learning from the results. Intelligence is necessary, but not sufficient. New knowledge is…
Augmenter la TVA n’a de sens que si ce n’est pas répercuté sur les allocations sociales. Si les prestations sociales sont alignées sur l’indice des prix, la hausse de la TVA est répercutée sur les pensions et allocations, et donc finit par retomber sur les facteurs de…
▶️️️#Économie - Salaire : S. Lecornu veut rapprocher le brut du net “On devrait augmenter la TVA.” @pascalperri #24hPujadas #LCI #La15 ⤵️
Il faudrait plutôt supprimer ce quota. Tout ce qui compte c’est de construire. Si vous construisez un logement de standing la personne qui l’occupera libère une autre logement et par un jeu de chaises musicales cela profite aussi aux familles à bas revenus. Ce que la recherche…
🎙️ @karim_bouamrane : "Je propose une peine d'inéligibilité pour les maires s'ils ne respectent pas les 25 % de logements sociaux prévus par la loi." #GGRMC
We also track their locations at any time and we can serve them "add" for a topic if more than n people vote on it online
I suggest we propose a counter-law to this: ⚖️ PoliticianControl Where all European citizens can read any EU politician's chats at any moment To keep them all in check
🇪🇺 My fellow Europeans You have to fight ChatControl 💪 Don't let @vonderleyen read your chats! metalhearf.fr/posts/chatcont…
metalhearf.fr
ChatControl wants to scan all your private messages
The EU is pushing legislation that would scan all our private messages, even in encrypted apps.
🚀 Excited to share scPortrait! Led by Sophia Mädler & Niklas Schmacke w/ the Mann lab — a new @scverse tool for standardized single-cell image data. Enables ML-ready extraction, >1B cell processing, cross-omics, & cancer macrophage insights. 🔗 biorxiv.org/content/10.110…
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