Liz
@DeHelenos
Microbióloga y bioanalista. Magíster en Microbiología. Metabolismo de Neoplasias hematológicas, Biología Celular y Molecular, Salud Pública.
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Mitochondria coordinate far more than ATP. 🔻 Cytochrome c → apoptosis 🔷 H₂O₂ → redox + protein thiol signaling 🔴 NADH/NAD⁺ → integrated stress response 🔺 AMPK → metabolic/catabolic shift 🧬 mtDNA/mtRNA → innate immune activation 💠 TCA metabolites → chromatin +…
Representación esquemática del espectro de la tuberculosis (TB), que abarca desde la eliminación espontánea, la infección latente por Mycobacterium tuberculosis, la TB incipiente, la TB subclínica y la enfermedad activa: Clin Microbiol Rev 2026:e0019425.
Proteins aren’t just something you eat; they’re the actual machinery that keeps you alive. Once you see how many layers of structure a protein has to go through just to work, it makes sense why biology is as precise (and fragile) as it is. At the top, you’ve got the basics:…
Pathogens accelerate features of human aging: A review of molecular mechanisms sciencedirect.com/science/articl…
🔋 Mitochondria run their core power system using bacterial-style DNA. 🧬 But they need your nuclear DNA for support, repair, and growth. Think of it like a battery with its own mini-engine; it sparks on its own, but the car (your cell) builds and maintains it. Mitochondria…
Metaflammation’s Role in Systemic Dysfunction in Obesity: A Comprehensive Review mdpi.com/1422-0067/26/2… Metaflammation’s role in systemic dysfunction in obesity
Where vitamins and minerals are stored in the body Vitamins and minerals use different storage strategies. Some are stockpiled in organs and tissues, while others are used immediately and must be replenished often. Storage pattern explains why some deficiencies appear quickly…
Impressive synthesis and integration of concepts around the Energy Resistance Principle @msahsorin
bsahely.com/2025/10/10/the… The Energy Resistance Principle: How Life Balances Power, Flow, and Meaning | ChatGPT5 & NotebookLM Every system that endures — cellular, social, or planetary — must balance the energy it generates with the capacity it has to channel that energy without…
Welcome to the Mitoverse 😀 Great introductory piece on mitochondria from @mitoworld_org stemmagazine.com/gOCT25/viewer/…
Crazy example of Chinese biotech cycle times: I'm reading a new bioRxiv preprint from a Chinese research team about a new circular RNA modality. It's about a cool idea to embed aptamers into circular RNAs. The circularity confers stability and the aptamers confer targeting. So…
Oncolytic viruses have the unique ability to selectively replicate within (and to destroy) cancer cells, offering a promising approach in cancer treatment. A new Review summarises clinical progress, remaining challenges, & future research directions: hubs.li/Q03Kgclb0
Mitochondria move thru the body. Free mitochondria can be exported by brown fat cells into the bloodstream. From there, they transit to cells with damaged mtDNA, where they are imported and rescue mitochondrial function. The implications for cancer therapies are profound.…
Without resistance, nothing can be transformed into anything else. x.com/MitoPsychoBio/…
How does energy keep us alive? Our bodies are resistive energetic circuits where electrons flow from food→oxygen in our mitochondria. It's only through energy resistance (éR) - like electrical resistance - that transformation of energy into life is possible. The Energy…
The ERP paper with @msahsorin and our thoughts on the bridge between the physics of energy and biology come out next week 😃
The cycle of life, every instant, in your mitochondria. The major electron carrier in mitochondria is NAD+. When it collects an electron from the food you eat, NAD+ is converted into NADH. NADH then feeds the electron to the electron transport chain so the electron can flow to…
“Por piedad, detengan esta guerra y dejen de matar inocentes” - Padre Romanelli, uno de los últimos sacerdotes católicos que quedan en Gaza 🇵🇸
Review @NatRevGastroHep @ljpally19 @iit_ucl @pallett_lab @BrownRom1 @george_e_finney Tissue-resident memory CD8+ T cells: master deciphers of the hepatic environment nature.com/articles/s4157…
Biomarcadores del envejecimiento: de lo molecular a la función fisiológica La mejor estrategia para vivir más y mejor no está en pastillas milagrosas, sino en hacer ejercicio, comer bien y poco, dormir adecuadamente y estar en paz con uno mismo y con los que te rodean.…
Oncolytic viruses have the unique ability to selectively replicate within (and to destroy) cancer cells, offering a promising approach in cancer treatment. A new Review summarises clinical progress, remaining challenges, & future research directions: hubs.li/Q03K5DlW0
Mental disorders are not brain disorders in isolation. Poor body health is a more pronounced manifestation of mental illness than poor brain health.
Results reveal the ΔΨM as the upstream signal conveying the mitochondrial status to the epigenome to regulate cellular biology, providing a new framework for how mitochondria can influence health outcomes in the absence of canonical dysfunction.
Mitochondrial membrane potential regulates nuclear DNA methylation and gene expression through phospholipid remodeling; 🧬 biorxiv.org/content/10.110…
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