ElowitzLab's profile picture. Lab of Michael Elowitz at Caltech. Synthetic biology and systems biology

ElowitzLab

@ElowitzLab

Lab of Michael Elowitz at Caltech. Synthetic biology and systems biology

This experiment came to life when I realized the negative control (two genes, same regulation) was intrinsically more interesting—and easier!—than the "real" experiment I had been planning... Thanks @NikoMcCarty!

Take two cells and place them side by side. Both cells have the same genome. And yet, oddly enough, they behave in different ways. They divide at different times and their RNA levels are distinct. Now let’s go one step further. Take those same two cells. But this time, imagine…

NikoMcCarty's tweet image. Take two cells and place them side by side. Both cells have the same genome. And yet, oddly enough, they behave in different ways. They divide at different times and their RNA levels are distinct.

Now let’s go one step further. Take those same two cells. But this time, imagine…
NikoMcCarty's tweet image. Take two cells and place them side by side. Both cells have the same genome. And yet, oddly enough, they behave in different ways. They divide at different times and their RNA levels are distinct.

Now let’s go one step further. Take those same two cells. But this time, imagine…


ElowitzLab reposted

Our #SynBioFH23 team have brought together an exciting programme to showcase how #bioscience technologies are impacting global healthcare approaches. #GlobalHealth Submit an abstract by 17 Jan 2023 for an opportunity to share your work.📅 Full details➡️bit.ly/3Dj2HHp

eventsWCS's tweet image. Our #SynBioFH23 team have brought together an exciting programme to showcase how #bioscience technologies are impacting global healthcare approaches. #GlobalHealth 

Submit an abstract by 17 Jan 2023 for an opportunity to share your work.📅
Full details➡️bit.ly/3Dj2HHp


ElowitzLab reposted

In 2000, a physicist named Michael Elowitz published one of the first synthetic gene circuits, called the "repressilator." By stitching three genes together, he endowed living cells with an artificial rhythm, coaxing them to flash green. Learn how he built it, and even play…


ElowitzLab reposted

I’ve always been interested in the stories behind BioNumbers. Textbooks say DNA polymerase, for example, replicates 220 nucleotides per second. But how do we know this? How can one actually measure the speed of a single enzyme? A fast typist, for comparison, types ~80 words per…

NikoMcCarty's tweet image. I’ve always been interested in the stories behind BioNumbers.

Textbooks say DNA polymerase, for example, replicates 220 nucleotides per second. But how do we know this? How can one actually measure the speed of a single enzyme?

A fast typist, for comparison, types ~80 words per…
NikoMcCarty's tweet image. I’ve always been interested in the stories behind BioNumbers.

Textbooks say DNA polymerase, for example, replicates 220 nucleotides per second. But how do we know this? How can one actually measure the speed of a single enzyme?

A fast typist, for comparison, types ~80 words per…
NikoMcCarty's tweet image. I’ve always been interested in the stories behind BioNumbers.

Textbooks say DNA polymerase, for example, replicates 220 nucleotides per second. But how do we know this? How can one actually measure the speed of a single enzyme?

A fast typist, for comparison, types ~80 words per…

Congratulations @ShiyuXia and @ucberkeley!

In January 2026, I will be joining Berkeley @UCBerkeley as an Assistant Professor in the Department of Chemical and Biomolecular Engineering, College of Chemistry @UCB_Chemistry, with exciting connections with world-class communities including the Lawrence Berkeley National…

ShiyuXia's tweet image. In January 2026, I will be joining Berkeley @UCBerkeley as an Assistant Professor in the Department of Chemical and Biomolecular Engineering, College of Chemistry @UCB_Chemistry, with exciting connections with world-class communities including the Lawrence Berkeley National…


ElowitzLab reposted

Added some tiny improvements to the flowcytometry app I made during my time in @ElowitzLab. Now it supports exporting gated events as npy and mat. So you can gate data in your favorite graphic interface, then analyze them with python or Matlab! ym3141.github.io/EasyFlowQ/Raw%…


Congratulations to @ShiyuXia and all of the outstanding CASI recipients!

BWF is pleased to announce the 2025 recipients of its Career Awards at the Scientific Interface (CASI). buff.ly/WDswUnt #bwfcasi

BWFUND's tweet image. BWF is pleased to announce the 2025 recipients of its Career Awards at the Scientific Interface (CASI). buff.ly/WDswUnt #bwfcasi


Beautiful paper from @sandynandagopal , Galit Lahav & colleagues. a seemingly “messy” circuit of dimerizing proteins (bHLH factors) can process a combinatorial input signals. Important step in more systematically understanding biological signal processing

How does one (signaling) arm know what the other is doing in the cell? Through a network of bHLH transcription factors obviously! Our work showing how neural stem cells integrate signals to coordinate a fate response is now out: cell.com/cell-reports/f…



I just love the great writing, beautiful books (and now...the capsule!) that @NikoMcCarty and others at @AsimovPress are creating.

Our second book is now available for pre-order. 🎉 Embracing the book's technology theme, we did something special: We encoded the entire book into DNA & packaged it into stainless steel capsules, where it will live for tens of thousands of years. 1,000 copies were made... 🧵



ElowitzLab reposted

How could we identify key genes involved in any biological process and cell type? Please read on about Nuclear In-Situ Sequencing (NIS-Seq) nature.com/articles/s4158…


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