Katie Galloway
@GallowayLabMIT
Assistant Prof @MITChemE ; mom^4 + wife; enjoys building cell-fate circuits, exploring dna topology, reprogramming the living world, and soccer; soli gloria deo
قد يعجبك
Delighted to bring gene circuits into a wide array of primary cells where they can be used for safe, effective gene therapies. 🧵 (1/n) Tremendous work by lead author @kaseyslove to dig into the details of these systems and figure out how to get these to work well! Original…
Loss of gene expression can compromise cellular fitness. In the case of such haploinsufficiency, replacement of the gene supplementation could rescue cell health. But what if you need a very precise dosage? Try ComMAND! 🧵 (1/n) Link: doi.org/10.1101/2024.0…
Come and join us @Stanford_ChEMH! It's an amazing place to do interdisciplinary research -- I feel very grateful to be part of this community. Faculty applications due 10/15/2025. Please share widely? Interested but worried you're not ready? DM me & I'm happy to provide advice :)
Open faculty position! We are seeking applicants for a tenure-track faculty position at the junior level (Assistant or untenured Associate Professor) with research programs that exist at the interface between molecular science and computation. Apply here: stanford.io/45MF3Qa
Beautiful trip to CSHL for Cell Fate Conversions The scenery, the science, the people...all so lovely! Very proud of Brittany and Mary who presented.
Gimme gimme gimme a man(uscript) after midnight
but there's not a soul out there... no one to hear my prayer....
but there's not a soul out there... no one to hear my prayer....
In the latest issue! A host organelle integrates stolen chloroplasts for animal photosynthesis dlvr.it/TN9RT1
Today is International #MyotonicDystrophy Awareness Day. Myotonic dystrophy may affect as many as 1 in 2,100 people across the world. Our tower will be illuminated in green this week to show support on the 5th annual awareness day💚 @MyotonicStrong ➡️myotonic.org
Astonishing 😆 I never imagined P21 PTM changes its stability that much😆. The cystine at aa41, when oxidized, largely stabilizes P21 at G2 and stops cell cycle progression in the daughter cells. Beautiful work! cell.com/molecular-cell…
🚨We have updated our STRAIGHT-IN Dual preprint! 🧵with all the details in the comments (1/n) Link: biorxiv.org/content/10.110… @GallowayLabMIT @nbwang22 @BenBlakeleyJ @annionna
So you want to engineer your hiPSCs, but targeting DNA payloads requires multiple slow, inefficient steps for each construct. What if we could accomplish multi-site integration seamlessly? 🚨Introducing STRAIGHT-IN Dual! 🧵 (1/n) Link: biorxiv.org/content/10.110…
Our new pre-print from the Greenberg and Churchman labs shows that activity-dependent modulation of RNA stability is a major, and underappreciated, mechanism of gene regulation in neurons. Tutorial below 👇 biorxiv.org/content/10.110… (1/11)
Legend David Baltimore died yesterday. He understood the way things should work: "the real contribution of @MIT is that it doesn't take itself too seriously. It takes ideas seriously, but the people are relatively informal. They are not self-aggrandizing the way academics can be.
Check out our work and software, led by the incredibly meticulous and capable @fanding_zhou! This is the culmination of work-in-progress presented a while ago at the 2022 Bioconductor Conference (see x.com/lcolladotor/st…).
Gene expression changes aren’t just about mean shifts — variability shifts matter too, especially for aging. We're thrilled to introduce QRscore, a flexible non-parametric framework for detecting shifts in mean and variance across conditions. doi.org/10.1016/j.crme… (1/7)
Is anyone else experiencing serious issues with uploading to zenodo? timeouts? stalling? #AcademicTwitter
JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada. We provide a generous startup, fully funded salary and academic appointment at U of Toronto. nature.com/naturecareers/… Please repost!
Is euchromatin really “open”? 🧬Our new study @bioRxiv suggests otherwise. Using super-resolution imaging🔬 @shiori_iida @MasaAShimazoe reveals: Euchromatin forms condensed domains in live cells. Cohesin constrains them and prevents domain mixing. 🔗biorxiv.org/cgi/content/sh… (1/3)
Transient gene melting governs the timing of oligodendrocyte maturation: Cell cell.com/cell/fulltext/…
WORK! My lab currently have 5 (!) open positions for postdocs/PhD students for: -Nanopore protein sequencing -Archaeal CDV cell division -Microfluidics for synthetic cells -Nuclear Pore Complex -Origami mimics of peroxisomes Please apply! ceesdekkerlab.nl/come-join-us/ RT=👍
Excited to have my second PhD student defend his thesis! Congrats, Dr Adam Beitz! @beitz_adam Adam is one of the Founders that joined in late 2019 and got into lab in 2020. How do cell convert? By finding a receptive state! Cheers to your resilience and brilliance! Excelsior!
Proteins dance. Molecular dynamics animate life, but their analysis is limited by the capabilities of current measurement technologies.
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قد يعجبك
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