FraticelliLab's profile picture. Quantitative Stem Cell Dynamics lab @IRBBarcelona led by @AlejoFraticelli
stem cells | hematopoiesis | lineages | epigenetic memories
Account run by students

Fraticelli lab

@FraticelliLab

Quantitative Stem Cell Dynamics lab @IRBBarcelona led by @AlejoFraticelli stem cells | hematopoiesis | lineages | epigenetic memories Account run by students

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Finally out in Nature our collaboration with the Velten Lab 🥰 Enjoy the reading! nature.com/articles/s4158…


Starting the week with a postdoc less in the lab and a nice farewell sentence on our office’s board 🥲🤍 Academia is tough when it comes to goodbyes.

FraticelliLab's tweet image. Starting the week with a postdoc less in the lab and a nice farewell sentence on our office’s board 🥲🤍
Academia is tough when it comes to goodbyes.

Fraticelli lab reposted

Wild paper that just got presented at the @EMBO #EMBOlineage2025 meeting. Crazy stuff. Congrats to the authors for a powerful (pun intended) finding!

Inheritable 'memory' genes drive #cancer drug tolerance, but their discovery in clinical samples is a major challenge. Our new theory, moving away from Luria-Delbruck, detects them from a *single* scRNA-seq dataset! With #ArchishmanRaju led by @suvranil_1 tinyurl.com/4pef8scy



Just wrapped up the #EMBO Lineage Tracing Workshop and we are already feeling nostalgic! Incredible science, inspiring discussions, and a spectacular location. Huge thanks to everyone who made it so special — see you again in two years! 💥

FraticelliLab's tweet image. Just wrapped up the #EMBO Lineage Tracing Workshop and we are already feeling nostalgic! Incredible science, inspiring discussions, and a spectacular location. Huge thanks to everyone who made it so special — see you again in two years! 💥

So proud of our PhD student Marta, presenting her story yesterday in the EMBO Lineage Tracing Workshop #EMBO Congrats 😍🥳

Presented a poster today at the Lineage tracing EMBO workshop in Sant Feliu de Guíxols🌞 So cool to interact with people from the field! @FraticelliLab @EMBO

mlopezosias's tweet image. Presented a poster today at the Lineage tracing EMBO workshop in Sant Feliu de Guíxols🌞 So cool to interact with people from the field! @FraticelliLab @EMBO
mlopezosias's tweet image. Presented a poster today at the Lineage tracing EMBO workshop in Sant Feliu de Guíxols🌞 So cool to interact with people from the field! @FraticelliLab @EMBO


🚀 Excited to kick off the Lineage Tracing EMBO Workshop in beautiful Sant Feliu de Guíxols! Looking forward to inspiring discussions and cutting-edge science. #EMBOWorkshop @AlejoFraticelli @leilaperie @IdoAmitLab @EMBO

FraticelliLab's tweet image. 🚀 Excited to kick off the Lineage Tracing EMBO Workshop in beautiful Sant Feliu de Guíxols! Looking forward to inspiring discussions and cutting-edge science. #EMBOWorkshop @AlejoFraticelli @leilaperie @IdoAmitLab @EMBO

Fraticelli lab reposted

Comentant ahir a @324cat @som3cat amb el @icreacommunity company @AlejoFraticelli @fraticellilab @IRBbarcelona l'utopia actual de viure 150 anys. Article de @DavidMeseguer 3cat.cat/324/la-quimera…

ManelEsteller's tweet image. Comentant ahir a @324cat @som3cat amb el @icreacommunity company @AlejoFraticelli @fraticellilab @IRBbarcelona l'utopia actual de viure 150 anys. Article de @DavidMeseguer
3cat.cat/324/la-quimera…

Fraticelli lab reposted

Excited to share our latest work @Nature! We show that the total number of hematopoietic stem cells (HSCs) in the body is restricted, challenging the classical model that HSC numbers are determined locally by the niche and introducing a new paradigm. (1/9) nature.com/articles/s4158…


Fraticelli lab reposted

Just as you start to feel like you've assembled an amazing team, everything is working, and all the projects have something interesting... people start/need to move on to their next career stage... There's no such thing as homeostasis for a PI.


Fraticelli lab reposted

If you want to know about Blood Stem Cell Aging, then THIS is the meeting to go to. I will be presenting the latest results of the @FraticelliLab regarding HSC memories and clonal dynamics. JOIN US !!!!! ehaweb.org/connect-networ…

AlejoFraticelli's tweet image. If you want to know about Blood Stem Cell Aging, then THIS is the meeting to go to. 
I will be presenting the latest results of the @FraticelliLab regarding HSC memories and clonal dynamics. 

JOIN US !!!!! 

ehaweb.org/connect-networ…

Our favorite cells are always dressing up quite heavily before FACS... we wonder if they enjoy the process 🙈😂 #AcademicTwitter

FraticelliLab's tweet image. Our favorite cells are always dressing up quite heavily before FACS... we wonder if they enjoy the process 🙈😂 #AcademicTwitter

Fraticelli lab reposted

Job offer! We are looking for a motivated postdoctoral researcher with expertise in cancer metabolism/immunology to investigate metabolic heterogeneity as a driver of cancer metastasis. @CBM_CSIC_UAM @criscancer #cancermetabolism #immunometabolism

BalsaEduard's tweet image. Job offer! We are looking for a motivated postdoctoral researcher with expertise in cancer metabolism/immunology to investigate metabolic heterogeneity as a driver of cancer metastasis. @CBM_CSIC_UAM @criscancer #cancermetabolism #immunometabolism

Fraticelli lab reposted

In Science, researchers present a new method to safely and preferentially generate CAR T cells directly inside the body using targeted lipid nanoparticles that deliver mRNA directly to T cells. The approach showed rapid and sustained immune reprogramming in preclinical models,…

ScienceMagazine's tweet image. In Science, researchers present a new method to safely and preferentially generate CAR T cells directly inside the body using targeted lipid nanoparticles that deliver mRNA directly to T cells. 

The approach showed rapid and sustained immune reprogramming in preclinical models,…

Fraticelli lab reposted

Fantastic data shared and discussed at the 3rd YERM session on cell fate and cell plasticity including normal and malignant hematopoiesis. #EHA2025

young_eha's tweet image. Fantastic data shared and discussed at the 3rd YERM session on cell fate and cell plasticity including normal and malignant hematopoiesis. 

#EHA2025

We are so proud of Marta Lopez ( @mlopezosias ) presenting her PhD work yesterday at @young_eha in Milan!! 🥰 🥳 She nailed it 💥🚀 #EHA2025 @EHA_Hematology

FraticelliLab's tweet image. We are so proud of Marta Lopez ( @mlopezosias ) presenting her PhD work yesterday at @young_eha in Milan!! 🥰 🥳 She nailed it 💥🚀 #EHA2025  @EHA_Hematology

If you are at #EHA2025, you cannot miss the talk given by Marta from our lab! 😍 Amazing story about HSC and development 👀

🚨 Just landed at #EHA2025 Excited for the coming days! Also - I'm speaking at #YoungEHA this Saturday (Session 3 - 14:00 Brown Hall 2) Come by to hear the latest from our lab 👩‍🔬✨ @FraticelliLab @AlejoFraticelli



Fraticelli lab reposted

Absolutely thrilled to share with you the final version of EPIclone, out now (open access) in @Nature. This has been an amazing collaboration with the lab of Lars Velten (@larsplus) at @CRGenomica nature.com/articles/s4158…


🎉 Today at #ISCO2025 in Berlin, Andrea Polazzi from our lab shared exciting preliminary results on a novel technology for studying cellular heterogeneity! 🧬 Incredible work, Andrea — we're proud of you! 👏 👉 isco-conference.eu

FraticelliLab's tweet image. 🎉 Today at #ISCO2025 in Berlin, Andrea Polazzi from our lab shared exciting preliminary results on a novel technology for studying cellular heterogeneity! 🧬 Incredible work, Andrea — we're proud of you! 👏
👉 isco-conference.eu

Fraticelli lab reposted

REGISTER NOW! 🚨🚨 Spots are filling up for the first EMBO workshop on Single cell Lineage Tracing 2025!! Sept 18-21 in Girona, Spain. Tons of opportunities for talks (short and full length) still available!!! meetings.embo.org/event/25-linea…


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