Ian McCracken
@IanMcCracken15
BHF Immediate Research Fellow @IdrmOxford | University of Oxford | Interested in all things cardiac development and regeneration
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Delighted to have been awarded this @TheBHF Immediate Fellowship working at @IdrmOxford to improve our understanding of coronary vessel development and regeneration
Congratulations to @IanMcCracken15, based in @IdrmOxford, who has been awarded an Immediate Postdoctoral Basic Science Research Fellowship by @TheBHF to improve understanding of the mechanisms underpinning formation of the coronary vessels! Read more: dpag.ox.ac.uk/news/ian-mccra…
🚨 Come and join our team! I’m recruiting a Research Assistant to work on a @TheBHF funded project on the molecular regulation of epicardial EMT. Closing date 11th May 2025. my.corehr.com/pls/coreportal… @kingscardio @Kings_BHFCentre @kingsmedicine #HeartDevelopment #Regeneration
Excited to share my work @GroupRiley, out today @NatureCVR: nature.com/articles/s4416… Using imaging, scRNAseq & computational modelling , we find that the neonatal cardiac conduction system can regenerate & demonstrate how MI-induced damage elicits arrhythmogenesis 🫀⚡️ 🧵[1/n]
We are looking for a new team member. Please check it out, apply and spread the word #postdoc #cardiovascular #cambridge jobs.cam.ac.uk/job/48385/
New pre-print from my lab, a useful resource for all interested in vascular gene regulation! We identify and characterise a cohort of mammalian arterial enhancers, alongside a re-examination of many previously reported endothelial enhancers @OxfordDPAG @IdrmOxford
A catalogue of verified and characterized arterial enhancers for key arterial identity genes. biorxiv.org/cgi/content/sh… #biorxiv_devbio
Nature research paper: Multimodal decoding of human liver regeneration go.nature.com/3wkmLb9
See link below for a 4-year postdoc in my lab in Edinburgh to study endothelial and platelet interactions in heart failure. This presents an exciting opportunity to travel and spend time in the laboratories of collaborators in the Netherlands and Germany. Please circulate!
Human and murine fibroblast single-cell #transcriptomics reveal #fibroblast clusters are differentially affected by #ageing and serum cholesterol Discover more 👉academic.oup.com/cardiovascres/… @escardio @ESC_Journals #scRNAseq #atherosclerosis #CardiovascularResearch
🌟🚨WE'RE HIRING🚨🌟 An incredible #postdoc opportunity, funded by the @EUeic 🇪🇺 to develop a novel human adenovirus for gene therapy in the brain or heart. Fixed term till April '27! elxw.fa.em3.oraclecloud.com/hcmUI/Candidat…
elxw.fa.em3.oraclecloud.com
Post-Doctoral Research Fellow
We are looking for a post-doctoral scientist to work on a cross European gene therapy programme.
🥳We are recruiting, please RT! I am delighted to advertise an exciting opportunity for a Senior Scientist with expertise in cardiovascular research and/or single cell informatics to join our team in @EdinUniCVS, funded by @TheBHF. Please get in touch or follow the link below! 🫀
We have a research assistant position available to work with me and @StoneOliverA. Join us to help set up in vitro models of human lymphatic endothelial cell development! Working in @OxfordDPAG at the @IdrmOxford. Details: tinyurl.com/StoneGroupRA @the_Node #devbio #stemcells
I am happy to communicate that SCENIC+ was published in @naturemethods. SCENIC+ is a workflow to infer enhancer-driven gene regulatory networks from scRNA-seq and scATAC-seq data. This work was done together with @Bravo_Potato at @steinaerts lab! 🧵1/9🧵 nature.com/articles/s4159…
Gene regulatory networks (GRNs) are useful models to understand cellular identity and disease. We have reviewed the GRN inference field in the current era of single-cell multi-omics 📖 out in @NatureRevGenet 🔗doi.org/10.1038/s41576… Full-text access: rdcu.be/dfpa2
Single-cell data from RNA-seq, chromatin accessibility, DNA methylation and other modalities can be readily integrated using two new methods #NBTNV go.nature.com/4222tNu
📢 Submit your abstract for the #CardiovascularRegeneration symposium @UniofOxford on 13 — 14 September 2023. This event will highlight the recent developments in the field of cardiac regeneration & development. 📅 Submit by 30 June 🔗buff.ly/3OVi0fd
Thrilled to share my PhD work in @CellCellPress! Massively parallel base editing to map variant effects in human hematopoiesis. We developed screens on blood stem cells to understand disease and develop treatments at single-nucleotide resolution.1/n cell.com/cell/fulltext/…
One of the most detailed models of a human cell. Obtained using X-ray, and cryoelectron microscopy:
High-plex protein and whole transcriptome co-mapping at cellular resolution with spatial CITE-seq go.nature.com/3koGTTC
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