You might like
Dr. Jianghong Zhong and colleagues at @Beihang1952 show that MTD retrotransposons play a crucial role in driving the early onset of #lupus by enhancing macrophage activation, which in turn promotes #ImmuneDysregulation. 🤩 Check it out: go.nature.com/4hVUOK4
Online Now: Megabase-scale loss of heterozygosity provoked by CRISPR-Cas9 DNA double-strand breaks dlvr.it/TPC5d9
Interleukin-1β (IL-1β) is secreted primarily by dying monocytes rather than by live bystander monocytes, challenging established models. #cryopyrin #pyrin #immunology #science nature.com/articles/s4159…
Comparative analysis of adenovirus, mRNA, and protein vaccines reveals context-dependent immunogenicity and efficacy @JCI_insight @harvardmed @BAwakoaiye insight.jci.org/articles/view/…
I would advise everyone to listen carefully to @davidrliu - which in my opinion is the most important scientist & innovator of our lifetime and the person who invented both Base editing & Prime editing - the 2 top leading modalities of Gene editing when he describes the grave…
Tonight’s episode of @60Minutes will include a segment on the impact of federally funded science and recent cuts to science funding. Our lab’s development of base editing and prime editing and their clinical applications will be among the work described in the episode.…
Nice paper in @ScienceMagazine apparently showing for the first time that DNA breaks leave lasting epigenetic scars Excitingly, it’s consistent with The Information Theory of Aging & our discovery of this same phenomenon in 1997, 1999, 2008 & 2023 🤣👏🧵 science.org/doi/pdf/10.112…
Viral vectors displaying peptide-MHC are versatile tools for activating and reprogramming antitumor CD8 T cells directly in vivo @ScienceAdvances @MEBirnbaum @MITdeptofBE @kochinstitute @ragoninstitute science.org/doi/10.1126/sc…
Pressure to publish jumps. And researchers have no time to do science. (New survey from Elsevier) Survey of 3200 researchers: 1. Only 45% of scientists have sufficient time for actual research. 2. For 68%, the pressure to publish today is greater than 2-3 years ago. 3. 29% of…
A great question. The reasons are not scientific. Technological challenges (likely constraining many people) are significant but decreasing. It’s time to transcend old thinking and rise to the challenge of biological systems.
Why is it that many people remain focused on gene level function? For decades we have known otherwise. There many reasons for the bias, some are technological, others are inherent to human intellect.
Led by Drs. Virginia Pascual, Jinghua Gu, and Simone Caielli, this work highlights distinct CD4 T cell subsets that may contribute to aberrant antibody responses and impaired immune regulation in systemic #lupus erythematosus. ➡️ More in @NatImmunol | go.nature.com/4o0Rbon
Immune cells called monocytes produce a key inflammatory protein called interleukin-1 beta (IL-1β) through an unconventional pathway in patients with lupus, according to new study from Dr. Virginia Pascual and Dr. Simone Caielli of @WCMpeds. Full story: bit.ly/4hdB0RR
CONGRESS | #EULAR2025 | PRESENTATION Jane E. Salmon, @WeillCornell, discussed results from the phase II IMPACT trial (NCT03152058) evaluating certolizumab in high-risk pregnancies with anti-phospholipid syndrome and lupus anticoagulant (N=51). The primary adverse pregnancy…
Mapping the placental galectin-3 interactome identifies CD9 and ITGB1 as functional glycoprotein counterreceptors during syncytialization | PNAS pnas.org/doi/10.1073/pn…
Did you know that today is #Kladdkakans dag? (Mud Cake Day). A #Swedish dessert best enjoyed together with whipped cream (#vispgrädde).😛 #kladdkakansdag
Dr. Lindsey Criswell Elected to National Academy of Medicine. Dr. Criswell is the NIAMS Director and is known for her research in SLE, RA, and Sjogrens. Congrats!! buff.ly/4fe8iyc
Researchers think certain common viruses may trigger some autoimmune conditions. At a recent OADR-ORWH talk, Dr. Judith James of @OMRF described how research from her lab pinned Epstein-Barr Virus as a potential trigger for lupus. Read more from NIH: nihrecord.nih.gov/2024/12/06/com…
Two phase 1 studies report promising outcomes with #CARTcell therapies in systemic #lupus erythematosus, but the next stage of development must address pitfalls around comparator arms and ancillary immune-modulating treatments. News & Views from Joan Merill and Judith James…
🆕 2025 ACR Guideline for Treatment of Systemic #Lupus Erythematosus 🦋 Just Released: Nov 3 #ACR25 🔥 🔸Review organ-specific treatment recommendations 🔸Steroid & HCQ Use Guidance ➠ Read the Full Guideline: acr.tw/47mkegj #RheumX #RheumTwitter #Rheum @RheumNow
We have observed a beautifully strange phenomenon of phase separation by human monocytes placed on soft matrix, which do it for survival. We model it by incorporating the Cahn–Hilliard equation with a Turing mechanism of local activation/global inhibition nature.com/articles/s4156…
United States Trends
- 1. Bama 12.4K posts
- 2. Ty Simpson 2,843 posts
- 3. Oklahoma 20.4K posts
- 4. South Carolina 32.5K posts
- 5. #UFC322 27.6K posts
- 6. Iowa 18K posts
- 7. #EubankBenn2 28.8K posts
- 8. Mateer 2,720 posts
- 9. Arbuckle N/A
- 10. Texas A&M 32K posts
- 11. Susurkaev 2,259 posts
- 12. Ryan Williams 1,561 posts
- 13. Beamer 9,277 posts
- 14. Sooners 3,884 posts
- 15. Talty 1,088 posts
- 16. Heisman 9,632 posts
- 17. Georgia Tech 2,340 posts
- 18. #FightOn N/A
- 19. Camilo 8,717 posts
- 20. #RollTide 2,701 posts
You might like
-
Bewersdorf Lab
@bewersdorflab -
Arthur Mortha
@nkg2d1 -
Rafael Irizarry
@rafalab -
Ifor Williams
@IforRWilliams -
Arjun Raj
@arjunrajlab -
John Nelson
@John_M_Nelson -
Miri Krupkin
@MiriKrupkin -
Prof. Lee Machado
@drleemachado -
Satheesh Kumar M.K.,PhD
@SatheeshKumarMK -
Mate Manczinger
@matemanc -
Niclas Thomas
@datasciimmunol -
Praveen Singh
@praveenvq -
Christophe Leterrier
@christlet -
Karina Ratiner
@KarinaRatiner
Something went wrong.
Something went wrong.