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Three color fiber photometry !!
Excited to share our Science paper on HaloDA1.0-the first genetically encoded far-red dopamine sensor! 🥳It enables powerful multiplex imaging in neurons, brain slices, and live animals.🧠🔬 #GRABsensors #Dopamine science.org/doi/10.1126/sc…
@LabLuthi congratulates @GFoustoukos for the Best Publication Award 2025 from the #SSSSC, the #Swiss Society for #Sleep Research, Sleep Medicine and #Chronobiology. A nice recognition of your outstanding research skills!👏 @fbm-unil.bsky.social @NatureNeuro @natneuro.nature.com
🧠 Paper alert! My scientific labour of love from my time at the @UKDRI at @ucl is now out in @NeuroCellPress ! Deep-layer 5/6 PV interneurons show early dysfunction in Alzheimer's models in vivo, tied to NPTX2 and GluA4 loss. 🔗 cell.com/neuron/fulltex… 🧵Thread below ⬇️
The @LabLuthi thanks #CIBM_ch organizers of the first #EEGResearch day - we enjoyed a very informative event and were glad to participate in a Duo Talk @unil #FBM #neuro
Congrats Min from @LabLuthi 👌!
A time window for memory consolidation during NREM sleep revealed by cAMP oscillation: Neuron cell.com/neuron/fulltex…
Deficient synaptic neurotransmission results in a persistent sleep-like cortical activity across vigilance states in mice: Current Biology cell.com/current-biolog…
👉👉New paper alert from @LabLuthi ! Newly promoted Dr. Cherrad, with @GFoustoukos, @FernandezLmj and others combines stimulation of sensory neurons from the #vagus nerve with #sleep, #heartrate, temperature and #locuscoeruleus recordings @unil #FBM #Neuro
Vagal afferent activation induces a NREM-sleep-like state with brain-body cooling, but locus coeruleus activation biorxiv.org/content/10.110… #biorxiv_neursci
Brava Francesca! Presenting for the first time her results on LC photometry-fMRI at an international conference #EMIM2025 🎙️ Always a special moment. More to come soon!
The night’s watch: Exploring how sleep protects against neurodegeneration: Neuron cell.com/neuron/fulltex…
Pupil size reveals arousal level fluctuations in human sleep nature.com/articles/s4146….
Here's our latest issue: cell.com/neuron/current The cover is for a Perspective piece by Lüthi & Nedergaard who discuss microarousals, and propose an inverted U-shaped relationship to reconcile their essential and disruptive roles: cell.com/neuron/fulltex… Cover by Nadia Alzoubi
Almost all neurons co-release peptides and small transmitters. Thrilled to share our latest research where new GRAB sensor promotes better understanding of the dynamics and molecular regulation between neuropeptide and neurotransmitter release in vivo. nature.com/articles/s4146…
It is an exciting time to be studying the functions of noradrenaline waves and micro-arousals in sleep 🧠💤 Take a look at this brand new review from @anita_luthi and Maiken Nedergaard on the subject
Anything but small: Microarousals stand at the crossroad between noradrenaline signaling and key sleep functions: Neuron cell.com/neuron/fulltex…
Maiken and I review here the brief awakenings from #sleep called #microarousals. They fragment sleep, but they are also integral to healthy sleep dynamics - so how to reconcile these opposing views? @LabLuthi @fbm-unil.bsky.social @anitaluthi.bsky.social
Online now: Anything but small: Microarousals stand at the crossroad between noradrenaline signaling and key sleep functions dlvr.it/THLG9T
Check out the landmark study of @NedergaardLab on #infraslow #locus #coeruleus activity in #NREM #Sleep and the link to blood volume, cerebrospinal fluctuations - 👏@NatalieHauglund 👏 from @LabLuthi
Out today in @CellCellPress ! We show that oscillations in norepinephrine and cerebral blood volume are the missing pieces that link NREM sleep to clearance of waste from the brain 🧠💤 cell.com/cell/fulltext/…
Infraslow noradrenergic locus coeruleus activity fluctuations are gatekeepers of the NREM–REM #sleep cycle @LabLuthi @anita_luthi @alejandrosoriof @GFoustoukos @CardisRomain nature.com/articles/s4159…
@LabLuthi uncovers a dual role of #locus @coeruleus in #sleep -> 1) its strict gatekeeper role for the sleep cycle 2) the partial brain-body arousals it generates. Powerful minds behind all this: @alejandrosoriof @GFoustoukos @CardisRomain nature.com/articles/s4159…
nature.com
Infraslow noradrenergic locus coeruleus activity fluctuations are gatekeepers of the NREM–REM sleep...
Nature Neuroscience - Lüthi and colleagues show that activity of the locus coeruleus (LC) is crucial for the cyclic alternation between non-rapid-eye-movement and rapid-eye-movement sleep....
👍@unil has noted a reduction in the number of animals 🐁used for research in 2023 compared with 2022. This is due in particular to increased efforts to integrate the 3Rs principle into all stages of the scientific process. news.unil.ch/display/172745…
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