Excited to share our latest study! 🧠✨ We reveal how non-direction-selective retinal ganglion cells encode motion beyond their receptive field, relaying the unconventional signals to the brain. A new insight into multimodal neurons in visual processing! pnas.org/doi/10.1073/pn…
A simple guide to understanding how neurons make neurotransmitters Your brain has different classes of neurons, each defined by the chemical messenger (neurotransmitter) they release. These transmitters are built from specific precursors using unique enzymes and cofactors. 1️⃣…
Arousal as a universal embedding for spatiotemporal brain dynamics Preprint: biorxiv.org/content/10.110… nature.com/articles/s4158…
Our fluorescence lifetime photometry at high temporal resolution (FLIPR) paper is now online at Neuron. FLIPR allows for fast (10Hz-1 kHz) and slow (min-hrs) measurement of absolute neuronal signals in freely moving mice. We highlight the utility by measuring tonic and phasic DA.
Online now: Absolute measurement of fast and slow neuronal signals with fluorescence lifetime photometry at high temporal resolution dlvr.it/TN1Sqp
A real-time all-optical interface for dynamic perturbation of neural activity during behavior: sciencedirect.com/science/articl… Real-time interface that integrates CaImAn for online calcium imaging analysis, and a custom hologram program for two-photon optogenetic stimulation.
A pair of papers on using holographic optogenetics and compressed sensing for connectomics Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing nature.com/articles/s4159…
Nature A compressed hierarchy for visual form processing in the tree shrew nature.com/articles/s4158…
Thrilled to share that our work is now published in @ScienceMagazine!✨ We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass!🧭 science.org/doi/10.1126/sc… 🧵1/
The human brain synchronizes visual signals by adjusting axonal conduction speed in the retina—revealing a previously unknown mechanism for precise perceptual timing @Annalis43262927 @FelixFranke7 @IOB_ch nature.com/articles/s4159…
Next-generation phenotyping of inherited retinal diseases: Eye2Gene (AI-driven algorithm). Better-than-expert accuracy for 63 common genetic causes. @ucl @npontikos @GeoMichalis @MaximilianPfau3 @sktywagner @riksag @KonBalaskas #NIH @NatMachIntell: brnw.ch/21wUfkJ
Karl and I wrote a short opinion piece on the importance of comparative neuroscience
To identify fundamental neuroscientific principles that generalize across species, systems and circuits, neuroscientists must embrace an evolutionary perspective, argue Karl Farrow and @KatjaReinhard. thetransmitter.org/systems-neuros…
Vision shapes representations of space in the hippocampus, whether you are a bird or a primate. It is sensory ecology doing its job... nature.com/articles/s4158…
Our latest work is out today in @NeuroCellPress . Using voltage imaging, we clarified how serotonergic neurons compute action effectiveness during learning behavior. With Ravid Haruvi, @zq_wei and @MishaAhrens sciencedirect.com/science/articl…
Now out in NatComms: Mice and monkeys spontaneously shift through comparable cognitive states - and it's written all over their faces! (1/7) nature.com/articles/s4146…
65 years after Lettvin’s bug detector neurons in the frog retina, we revisit how the retina drives behavior—from reflexes to prey capture to brain-state modulation New review with @AnnaIntegrated & Serena Riccitelli in Annual Review of Vision Science 👇 tinyurl.com/ymp3vs4d
The ON/OFF dichotomy is fundamental to visual processing. In a new study led by Flori Soto, we identify a conserved molecular mechanism establishing the OFF pathway. rdcu.be/eikoa
Our two-photon GABA imaging from mouse retina has been published! @Aki_Yz_Matsu in my lab spearheaded this project. I want to thank @LoogerL for molecular clustering and @janeliagenie for the amazing iGABASnFR2 sensor! nature.com/articles/s4159…
Must read new book by Nachum Ulanovsky!! The book outlines a new revolutionary approach for studying the brain closer to the natural behavior of animals and humans — namely, taking a more ecological approach to neuroscience.
Nachum's new book Natural Neuroscience is out! A fresh take on how brains work in the real world—well worth a read.
What are serotonin neurons trying to tell the brain? Our work on the question has been so much fun (@JCBeique , @JermiahYCohen, @grossmancooper ). Check out @efharkin_ 's exciting paper biorxiv.org/content/10.110… nature.com/articles/s4158…
Prof. Nachum Ulanovsky’s team found that bat hippocampal neurons, known for spatial mapping, also encode social info like identity, status & relationships - creating a unified social-spatial map of the world >> doi.org/10.1126/scienc… 📷Yuval Barkai @ScienceMagazine
After a long wait, our paper is out! We show that differences in learning between the sexes are modulated by the NPY receptor, which gates sensory perception. Great work led by PhD student, soon to be Dr, @kurien_sonu with @WormResearcher & @AsafGat7 nature.com/articles/s4146…
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