IPSC derived BS
@cwcm_ipsc
Regenerative medicine scientist turned VC and shit...
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CRISPR or shRNA? Why not both? Explore how combining #CRISPR knockout and #shRNA enhances gene function studies in iPSC-derived cardiomyocytes. Validate phenotypes with confidence and uncover deeper insights into cardiac differentiation. Read the full application note:…
1 week left to register for this #webinar! Dr. McMahon will discuss: ✨ Voltage imaging theory & practice ✨ Best practices in voltage imaging ✨ High-throughput functional phenotyping w/ voltage imaging in hiPSC-derived cardiomyocytes Secure your spot: hubs.ly/Q03GwHjH0
✨New #Citation: Published via @ScienceMagazine, @jankokaj & his team demonstrated a novel reprogramming strategy for the direct conversion of fibroblasts into neurons—within suspension 3D microcultures.🧠 💡Calcium Imaging Powered by Calbryte™ 520 science.org/doi/full/10.11…
🟧This is a game changer 🟧 Orange fluorescent calcium ion indicator (🟠OCaMP) with potential in vivo imaging applications: - Cortical neuronal activity🧠 - Whisker-evoked calcium activity in the barrel cortex - Detection of single action potentials⚡️ biorxiv.org/content/10.110…
When you need to get it right, ask Perplexity.
The tinder bio vs real life
These Sam courtroom sketches are getting more and more flattering.
An early win on the penultimate day of the @CPW_Plymouth cell physiology workshop. A cardiomyocyte contracting in response to 1 Hz electric field stimulation with the “cell” above it doing something rather less healthy! @Cairn_Research #cpw2023 #stillgoingstrong
It’s still #fluorescencefriday so here’s a cardiomyocyte showing off its titin (cyan) and actinin-2 (magenta)
The structure of the Dentate Gyrus in the hippocampus and its glial and neuronal diversity! 🧠🔬🤓 #neuroscience #confocalmicroscopy
While SARS-CoV2 infects Neurons, HIV prefers Microglia. HIV stored in these cells can become latent for decades while still replication-competent. After years, lymphoid and brain HIV sequences are distinct. Blood viremia doesn't detect🧠 HIV either. Markers: 🔴HIV🔵IBA1🟡Neun
Happy #FluorescenceFriday everyone! What better to enjoy this day than with some #colon #mucus 😊 #mucusmatters #FluorescentFriday #microscopy #mucusmayhem
Me knowing that #microscreepy/#spooktober season is only 6 Fridays away - I can't contain my excitement! Enjoy a happy #FluorescentFriday with some influenza virus "ghosts" #sciart #microscopy #fluorescencefriday
Some intestinal cells for #MicroscopyMonday #bioart #sciart #microscopy #immunofluorescence #intestine #histoart #pathart
The bar has been raised so high recently for #FluorescenceFriday. Ay yai yai....
These Sam courtroom sketches are getting more and more flattering.
What would it look like when Mickey matches with Minnie on Tinder?
For #FluorescenceFriday I present a matrix impression of calcium fluctuations in #dendrites of a Purkinje Cell imaged in vivo with two-photon microscopy in a mouse #cerebellum. Data courtesy of Kazuo Kitamura @kazkitamura at the University of Yamanashi, Japan. #microscopy…
My favorite day of the week #FluorescentFriday #pathart #bioart #sciart #intestine #histoart #underthemicroscope #microscopy
SEM of a marmoset heart showing the sarcomeres intercalated with mitochondria.
And don’t forget to check out the time lapse calcium imaging movies of rotavirus infection of MA104 cells with and without IP3R expression. Knockout of IP3R abolishes 🌊Ca2+ waves 🌊 but not the increased Ca2+ signaling within infected cells
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