Less_Sepulveda's profile picture. 🔬♀️Embryologist and stem cell biologist
☕ Coffee addict
🍺 Beer lover
🏊‍♀️🏋️‍♀️🏃‍♀️ Fitness freak
⚠️ Calcium Oxalate kidney stone maker

Lessly

@Less_Sepulveda

🔬♀️Embryologist and stem cell biologist ☕ Coffee addict 🍺 Beer lover 🏊‍♀️🏋️‍♀️🏃‍♀️ Fitness freak ⚠️ Calcium Oxalate kidney stone maker

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My latest paper is out! thanks to all the authors and @MRC_LMS for a great effort. We questioned the potency of mouse primordial germ cells (PGCs) and propose that PGCs exhibit a latent pluripotency. Brief summary and pretty videos below. Check it out sciencedirect.com/science/articl…


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Remembering our much-loved and missed babies. They will never be forgotten 💜🧡🕯️ #WaveOfLight #BLAW #BabyLossAwarenessWeek #BabyLoss #PregnancyLoss


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New Paper Alert 🥳Our work showing that histone modifications are critical for regulating the specification of epiblast and primitive endoderm lineages in rabbit blastocysts has just been published ! rdcu.be/d52Qv

Epi_Nath's tweet image. New Paper Alert 🥳Our work showing that histone modifications are critical for regulating the specification of epiblast and primitive endoderm lineages in rabbit blastocysts has just been published ! 
rdcu.be/d52Qv

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Maybe my last post here? ---> Follow the lab on 🦋🦋🦋 ! Happily retweeting new preprint: @Paul_Chammas postdoc paper @MRC_LMS , teasing apart Dux vs MERVL in the 2C-like state. Not all 2C-like cells are created equal....

Happy to share our latest #preprint showcasing the work done during my postdoc in the lab of @MPercharde at the @MRC_LMS. We used CRISPRa to disentangle the close relationship between Dux and MERVL elements in the induction of the 2-cell like state. biorxiv.org/content/10.110… (1/8)

Paul_Chammas's tweet image. Happy to share our latest #preprint showcasing the work done during my postdoc in the lab of @MPercharde at the @MRC_LMS. We used CRISPRa to disentangle the close relationship between Dux and MERVL elements in the induction of the 2-cell like state. biorxiv.org/content/10.110… (1/8)


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Happy to share our latest #preprint showcasing the work done during my postdoc in the lab of @MPercharde at the @MRC_LMS. We used CRISPRa to disentangle the close relationship between Dux and MERVL elements in the induction of the 2-cell like state. biorxiv.org/content/10.110… (1/8)

Paul_Chammas's tweet image. Happy to share our latest #preprint showcasing the work done during my postdoc in the lab of @MPercharde at the @MRC_LMS. We used CRISPRa to disentangle the close relationship between Dux and MERVL elements in the induction of the 2-cell like state. biorxiv.org/content/10.110… (1/8)

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Academic Women Association (AWA) is back, with a Christmas networking event 🎄 When: Thursday 5th December, 3.30 pm Where: Ex Libris, 1st floor Commonwealth building, Hammersmith Campus Book Here: lnkd.in/dctgTt48

Ilaria_Bell's tweet image. Academic Women Association (AWA) is back, with a Christmas networking event 🎄 
When: Thursday 5th December, 3.30 pm
Where: Ex Libris, 1st floor Commonwealth building, Hammersmith Campus
Book Here: lnkd.in/dctgTt48

Many congratulations to Miguel! He will be part of our mentoring session at the GRS Germinal stem cell biology 2025. You can apply now grc.org/germinal-stem-…


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Sending love to all of the babies in Heaven and their families on Earth. Shine on in paradise little angels. @allontheboard #BabyLossAwarenessWeek #BabyLoss #BLAW

allontheboard's tweet image. Sending love to all of the babies in Heaven and their families on Earth. Shine on in paradise little angels. @allontheboard 

#BabyLossAwarenessWeek #BabyLoss #BLAW

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Our work establishing the orphan nuclear receptor NR5A2 as an essential regulator of early mouse development is finally out! We show that NR5A2 is required for the development of a viable morula. doi.org/10.1126/scienc…


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Happy Pluripotency Day! #OCT4 🧫


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In April, Professor Petra Hajkova, deputy director of the @MRC_LMS, was awarded the prestigious Cheryll Tickle Medal. This medal is awarded annually to mid-career, female scientists for outstanding achievements in the field of Developmental Biology. lms.mrc.ac.uk/petra-hajkova-…

MRC_LMS's tweet image. In April, Professor Petra Hajkova, deputy director of the @MRC_LMS, was awarded the prestigious Cheryll Tickle Medal. This medal is awarded annually to mid-career, female scientists for outstanding achievements in the field of Developmental Biology.
lms.mrc.ac.uk/petra-hajkova-…

We’re looking back over the first half of 2024 at the outstanding achievements of our #womeninscience at the @MRC_LMS. We’re proud to see our scientists being recognised for their groundbreaking work. Congratulations to all of you!🎉



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EMBO Gold Medal awarded to Elvan Böke @LabBoke to recognize her pioneering research on physiological mechanisms that enable oocytes to stay healthy over decades of dormancy @CRGenomica embo.org/press-releases…


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In the spirit of #MentalHealthAwarenessWeek I am really grateful to my colleagues @ImperialMed @MRC_LMS and in the #devtranscon lab for making this a great place to work - massive thanks to Laurence Game for leading us through our local Nature Reserve @ScrubsAction

metzisv's tweet image. In the spirit of #MentalHealthAwarenessWeek I am really grateful to my colleagues @ImperialMed @MRC_LMS and in the #devtranscon lab for making this a great place to work - massive thanks to Laurence Game for leading us through our local Nature Reserve @ScrubsAction

Great mouse work done by @Pranay_Shahh and the human side by @CamilleDion15! Congratulations to all the collaborators!!!

Delighted to share our most recent paper explaining why DNA Translesion Synthesis (TLS) is required for fertility. Huge amount of work from @Pranay_Shahh and a great collaboration with @ReikLab at Altos Labs, @HGLeitch and the Garaycoechea Lab @_Hubrecht Institute (link below)



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Last chance to register for the Women’s Health in the Workplace event, a safe space to discuss health challenges (physical and mental) faced by women in the academic workplace and the policies around them. imperial.ac.uk/events/174591/… @ImperialSandC @ImperialMed @imperialcollege

Our next event "Women’s Health in the Workplace" co-hosted by Women’s Health Network of Excellence, Academic Women Association and Women in Academic Medicine, is approaching! More information and registration below 👇 imperial.ac.uk/events/174591/…



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Congratulations to Petra Hajkova ⁦@MRC_LMS⁩ on a tour de force presentation and the award of the Tickle Medal ⁦@_BSDB_

metzisv's tweet image. Congratulations to Petra Hajkova ⁦@MRC_LMS⁩ on a tour de force presentation and the award of the Tickle Medal ⁦@_BSDB_⁩

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Preprint alert! With Irene Amblard @CroBeaver @BorisLenhard @ImperialMed @MRC_LMS we dissect a regulatory circuit that operates during mouse caudal body dev to control Cdx2 Spoiler alert - a single motif switch converts a silencer into an enhancer: biorxiv.org/content/10.110…


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What a fantastic inspirational talk we had at our last AWA event by Prof Helena Teede! Thank you everyone for coming, stay tuned for the next AWA event in April. #AWA #AcademicWomenAssociation

A huge thank you to the fantastic speaker @HelenaTeede, and to the organisers @HelenaTeede @NinaModerau @Ilaria_Bell @AWHLproject @MRC_LMS, as well as all those who attended. Find out more about the AWA and how you can join ⬇️ imperial.ac.uk/department-sur…

ImperialSandC's tweet image. A huge thank you to the fantastic speaker @HelenaTeede, and to the organisers @HelenaTeede @NinaModerau @Ilaria_Bell  @AWHLproject @MRC_LMS, as well as all those who attended. 

Find out more about the AWA and how you can join ⬇️

imperial.ac.uk/department-sur…


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