Our multi-chamber cardioid paper is finally out! Big thanks to the whole team & collaborators, #IMBA for their continuous support, and the reviewers & editors for facilitating further improvements. Thank you!
Now online! Multi-chamber cardioids unravel human heart development and cardiac defects dlvr.it/SzRL7b
Breakthrough in #IonChannels research 👀 International researchers from @univienna & @WUSTL have made significant progress in understanding the "gating" process of Kir2 potassium channels. Read more in @NatureComms ⤵ nature.com/articles/s4146…
nature.com
Subunit gating resulting from individual protonation events in Kir2 channels
Nature Communications - Here, authors introduced negative charges in the transmembrane helices in Kir2.2 channels generating pH-dependent sub-conductances. Molecular dynamics simulations show how...
📢 Starts tomorrow! The EpIC [Electrophysiology and Ion Channels] Seminar series features outstanding early stage investigators and cutting-edge topics. Pls, register (free) and RT! sgp-epic-seminars.com Inaugural session presented by Willow Coyote-Maestas @willowcoyote
![OsamaHarraz's tweet image. 📢 Starts tomorrow!
The EpIC [Electrophysiology and Ion Channels] Seminar series features outstanding early stage investigators and cutting-edge topics. Pls, register (free) and RT! sgp-epic-seminars.com
Inaugural session presented by Willow Coyote-Maestas @willowcoyote](https://pbs.twimg.com/media/FvDcu8mXoAAi-P_.jpg)
Very happy to see our work published! Thank you to everyone involved, especially @TomTomIBK who I humbly shared first authorship with, and @moonii1020 for the great collaboration. #retina #ionchannels #calciumchannels #electrophysiology #compchem
Happy to share the most recent paper #structurally and #biophysically characterizing two disease-causing Cav1.4 mutations. Great collaborative effort with KoschakLab. @CavX_PhD @uniinnsbruck #retina #compchem tandfonline.com/doi/full/10.10…
tandfonline.com
Characterization of two pathological gating-charge substitutions in Cav1.4 L-type calcium channels
Cav1.4 L-type calcium channels are predominantly expressed at the photoreceptor terminals and in bipolar cells, mediating neurotransmitter release. Mutations in its gene, CACNA1F, can cause congeni...
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