WickmanLab
@WickmanLab
We study cell signaling in the heart and brain and are always looking for new team members!
You might like
Our systematic investigation of G protein coupling profiles of 100+ #GPCRs driven by the one and only Ikuo Masuho is out after ~10 years of work. We see many interesting patterns with the help of AI. Check it out- there is a useful reference table. doi.org/10.1016/j.celr…
Thank you Dr. Amy Arguello for speaking in our MDT on Addiction seminar series on November 7th & sharing your research with our team. Your presentation titled, “Adolescent drug use and relapse-like behavior” was very informative. @UMN_MDTA
So glad to see this out! Dual-polarity voltage imaging—a multi-year, multi-lab effort to unveil the concurrent dynamics of multiple cell types in awake animals. In collaboration with @ganeshvasanc, Schnitzer lab, @ChengHuangThu, @jess_cardin, @vpieribone science.org/doi/10.1126/sc…
A @NatureBiotech paper presents a method called EEL FISH that profiles spatial transcriptomes in single cells in large, complex tissue samples. go.nature.com/3Rfr1NJ
Laboratory of Structural Biology of Disease led by Fang Li, PhD has published a new paper in PNAS, which offers evidence for possible animal origin of the COVID-19 omicron variant. med.umn.edu/news-events/re…
Reward and aversion processing by input-defined parallel nucleus accumbens circuits in mice ift.tt/4dA7059
nature.com
Reward and aversion processing by input-defined parallel nucleus accumbens circuits in mice
Nature Communications - The nucleus accumbens (NAc) is involved in mediating reward seeking and negative valence. Here, the authors present evidence for afferent-specific circuitry of the NAc in...
Wow from @miketadross "we demonstrate robust, bidirectional editing of chemical neurotransmission. We provide for distribution of validated reagents, community design principles, and synthetic building blocks for application to diverse pharmaceuticals." biorxiv.org/content/10.110…
Big wins for MPaT students Apoorva & Adidti in the 3-Minute Thesis competition. Adidti Bapat took 3rd place🏆! Apoorva Limaye took 1st place🏆 with her talk "Unraveling protein dynamics to facilitate rational drug designing" & moves on to the University-wide competition in Nov.!
'..optogenetic and chemogenetic activation of residual PV+ INs effectively ameliorated depressive-like behavior and rescued short-term spatial memory in AD mice..' nature.com/articles/s4138…
nature.com
Prefrontal parvalbumin interneurons deficits mediate early emotional dysfunction in Alzheimer’s...
Neuropsychopharmacology - Prefrontal parvalbumin interneurons deficits mediate early emotional dysfunction in Alzheimer’s disease
A game changer for neuroscience: MRI with millisecond precision. Out now in @ScienceMagazine science.org/doi/10.1126/sc…
Student Spotlight: Anisha Adke is starting her first year of PhD in the Molecular Pharmacology and Therapeutics Graduate Program. She has been a leader in our program’s M1/M2 antiracism education series. Keep up the good work!
A new RNA-editor invented by @DukeNeuro’s Josh Huang let's scientists monitor + manipulate brain cells w/ unprecedented selectivity and ease. It might also be an effective route to treat complex diseases like epilepsy or cancer (reported in @Nature today). today.duke.edu/2022/10/new-rn…
today.duke.edu
New RNA-Based Tool Can Illuminate Brain Circuits, Edit Specific Cells | Duke Today
New RNA-Based Tool Can Illuminate Brain Circuits, Edit Specific Cells | Duke Today
Study helps to explain the higher prevalence of Alzheimer's disease in women. X-linked ubiquitin-specific peptidase 11 increases tauopathy vulnerability in women #AlzheimersDisease @CellCellPress cell.com/cell/fulltext/…
cell.com
X-linked ubiquitin-specific peptidase 11 increases tauopathy vulnerability in women
For women, the risk of developing Alzheimer’s disease is significantly higher than for men. In this study, Yan et al. uncover a molecular mechanism underpinning the heightened susceptibility.
We (with @azayhara and @hongyu_chang ) wrote a mini-review on recent advances in optogenetics: integrated opto-electrodes for near cell resolution stimulation, closed-loop manipulations,etc. We discuss new exciting types of experiments this tech enables. cell.com/trends/neurosc…
Meet Dr. Martha Streng. @geewhiz_ephys is a postdoctoral fellow in the Krook-Magnuson lab st U. of Minnesota. Her research is focused in cerebellar interventions for temporal lobe epilepsy.
Gophers for Puerto Rico are collecting funds to help the island in the aftermath of Hurricane Fiona! Pueblos are still without power and resources! Help us by donating and sharing widely! #MedTwitter #doubledocs #sciencetwitter gofund.me/ff1f5370 #GoFundMe
gofundme.com
Donate to Gophers for Puerto Rico: Hurricane Aid Fundraiser, organized by Alexis Cotto-Rosario
If you are in the UMN area and have donated at least $10, you c… Alexis Cotto-Rosario needs your support for Gophers for Puerto Rico: Hurricane Aid Fundraiser
#UMNProud of Dr. Brian Trieu (PhD 2022)!
Brian has also helped to create a more equitable environment in academia through different efforts, two of which include developing a mentorship program for URM students and serving on his PhD program’s first DEI committee. Good luck in clinic, Brian!
Rejuvenation of the aged brain immune cell landscape in mice through p16-positive senescent cell clearance ift.tt/FElZfXG
New Research: DNA methyltransferase activity in the basolateral amygdala is critical for reconsolidation of a heroin reward memory: The persistence of drug memory contributes to relapse to drug seeking. The association between… frontiersin.org/articles/10.33… #Molecular #Neuroscience
United States Trends
- 1. Valentines Day N/A
- 2. Good Saturday N/A
- 3. #RISERCONCERTD2 N/A
- 4. Lucas Raymond N/A
- 5. #ElAmorLoVenceTodo N/A
- 6. JASPER 2ND RISENSHINE N/A
- 7. #SaturdayVibes N/A
- 8. Range Rover N/A
- 9. #SaturdayMotivation N/A
- 10. Bayes N/A
- 11. #いきづらい部1st_Day1 N/A
- 12. Solar N/A
- 13. St. Valentine N/A
- 14. Senior Day N/A
- 15. Reid Hoffman N/A
- 16. MATCH DAY N/A
- 17. Restore Britain N/A
- 18. Tory N/A
- 19. Zona 7 N/A
- 20. MEET DAY N/A
Something went wrong.
Something went wrong.