Tal vez te guste
A new review paper led by @mj_dahl, Agnieszka Kulesza and @WB_Markus. We review how deficient #dopaminergic and #noradrenergic modulation of hippocampal plasticity may contribute to memory loss in aging and Alzheimer's disease sciencedirect.com/science/articl… #locuscoeruleus
We recently showed age-dependent alterations to locus coeruleus in the presence of tau pathology: sciencedirect.com/science/articl… Want to know the molecular signatures that potentially drive these changes? Come chat with me during lunch at Poster 123 tomorrow July 18 at #AAIC2023!
In this new preprint postdocs Meike van der Heijden & Amanda Brown set out to answer the question "why can cerebellar dysfunction present itself as different motor disorders?" They find and optogenetically confirm different spike signatures for ataxia, dystonia, and tremor.
Neural spike signatures determine the behavioral presentation of cerebellar disease biorxiv.org/cgi/content/sh… #bioRxiv
New pre-print led by @EmilyDPrevost identifying the Monosynaptic inputs to ventral tegmental area glutamate and GABA co-transmitting neurons biorxiv.org/content/10.110…
Latest preprint from the lab looking at norepinephrine and dopamine release dynamics in dorsal CA1 during contextual fear conditioning. biorxiv.org/content/10.110…
It's that time of year! The Emory Neuroscience program is hold an open house on Wed November 2nd, 5-6pm EST. Come learn more about the application process and what life would look like as a grad student in Atlanta! RSVP here: forms.gle/qP8avsxS3reiSN…
In vivo tractography of human locus coeruleus—relation to 7T resting state fMRI, psychological measures and single subject validity | Molecular Psychiatry nature.com/articles/s4138…
Finally OUT!!! very proud of this work led by Loic Broussot and @ContesseThomas Completely unexpected role of a LDTg GABA input to the VTA to promote fear freezing. Check out full article here (open access) and don’t skip the sup. video! nature.com/articles/s4138…
nature.com
A non-canonical GABAergic pathway to the VTA promotes unconditioned freezing
Molecular Psychiatry - A non-canonical GABAergic pathway to the VTA promotes unconditioned freezing
Beautiful!
Neural spike signatures determine the behavioral presentation of cerebellar disease biorxiv.org/cgi/content/sh… #bioRxiv
NEW PREPRINT FROM THE LAB📢📢: Locus Coeruleus firing patterns selectively modulate brain activity and dynamics! 3y in the making and this work is finally seeing light thanks to a fantastic teamwork! C Grimm, S Duss and @BohacekLab. Short thread ⬇️ biorxiv.org/content/10.110…
The Neurotox Virtual Special Issue in ACS Chemical Neuroscience is out! Guest editor Heather Patisaul and I compiled work from experts in a range of fields to clarify mechanisms that underlie adverse impacts on the nervous system. @NCStateSciences 👇 pubs.acs.org/articlesonrequ…
pubs.acs.org
Virtual Issue: Neurotoxicology
Virtual Issue: Neurotoxicology
Our recent work "A distinct astrocyte subtype in the aging mouse brain characterized by impaired protein homeostasis" made it to the Cover of @NatureAging August issue! Volume 2 Issue 8, August 2022 - nature.com/nataging/volum…
First published article from my lab! It will be useful for labs using water restriction to motivate behavior. eneuro.org/content/8/6/EN…
eneuro.org
Three Water Restriction Schedules Used in Rodent Behavioral Tasks Transiently Impair Growth and...
Water restriction is commonly used to motivate rodents to perform behavioral tasks; however, its effects on hydration and stress hormone levels are unknown. Here, we report daily body weight and...
🔵Exciting new work from Sebastian Bouret's lab for all #LocusCoeruleus lovers: "Our data show that LC neurons dynamically track the amount of effort produced to face both cognitive and physical challenges with subsecond precision." Also data on reward!🐵 journals.plos.org/plosbiology/ar…
"Safer" chemical replacements for banned flame retardants may not be as safe as once thought. Research from @NCStateBioSci shows that they may pose a risk to brain development in children. Learn more: ncst.at/J7JP50GTxHL
AAVs to express PPO for inhibiting synaptic projections in vivo are now available from Addgene. If anyone has any questions about using them for your terminals of interest, please reach out!
Plasmids from @mbruchas: A photoswitchable GPCR-based opsin for presynaptic silencing. hubs.la/H0-jKZn0
For anyone interested in reading about the super cool research I do in the lab of the brilliant Dr. Shannon Farris, give this a click and check it out! (we're also looking for a new research assistant, link in article 🤓)
How do we recall faces, names, and where and when we met someone? With a new @NIH R01, @sfarris721's lab is studying the bioenergetics, molecular cues, and distinct cell types that encode social memories in the brain’s hippocampus. #Neuroscience #Memory vtx.vt.edu/articles/2021/…
news.vt.edu
Neuroscientists explore differences in mitochondria of memory cells in the brain with new NIH...
With a new five-year, $2-million National Institutes of Health grant, Shannon Farris, assistant professor at the Fralin Biomedical Research Institute at VTC, is mapping out the diverse bioenergetic...
Tagging active neurons by soma-targeted Cal-Light biorxiv.org/cgi/content/sh… #biorxiv_neursci
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