Silvia Monteagudo
@SilviaMonteag
Associate Professor, KU Leuven - Cartilage biology and Osteoarthritis (Tissue Homeostasis & Disease lab)
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Our paper showing that sphingomyelin 34:1 (⬆️ in🧍osteoarthritis synovial fluid) sensitises🐁sensory neurons in vitro & causes pain behaviours + knee-innervating neuronal hyperexcitability in 🐁 in vivo is now out in @OACJournal sciencedirect.com/science/articl… Tweetorial 👇 #neuroscience
Pain = main driver of clinical decision making in osteoarthritis (OA). Our lab studies OA pain mechanisms. During OA, multiple cell-cell interactions occur, many mediators being released that alter the contents of the synovial fluid. #neuroscience #pain journals.lww.com/pain/Fulltext/…
Congratulations Dr Reem!! I am very proud! You did excellent yesterday, and you have done an amazing job in your PhD 🎉🤩💪🏻
Thrilled to share I’ve successfully defended my PhD thesis; Inhibition of histone demethylases to restore H3K79 methylation in OA.” 🎉 Huge thanks to my supervisors, @SilviaMonteag & @TissueHomandDis, and to my jury Cristina Ruiz Romero, Jessica Bertrand, @LuVaDeBo and @CoolsJn!
Unlocking a Detrimental Role of IGF1 in Osteoarthritis: A New Target for Therapeutic Intervention? | Research Communities by Springer Nature communities.springernature.com/posts/unlockin…
Check out our new publication @NatureComms that unlocks a detrimental role for IGF1 in #osteoarthritis! 👇🏻
New @NatureComms Publication Alert! We uncover a Wnt/IGF1 link driving joint damage in #osteoarthritis. IGF1, induced by Wnt signaling, worsens the joint disease, but IGF1 targeting could open doors to new therapie. rdcu.be/dXZ7l @SilviaMonteag @AnaEscribano7 1/14
Dr. Rik Lories, Professor @KU_Leuven and Chair of the Division of Rheumatology @UZLeuven, speaker for the 3rd International Workshop on the Epigenetics of #OA, will present on Day 2 of the event, Sept 5, 2024, in Session 6: Pharmacological Modulation of the OA Epigenome. His talk…
📢Happy to share our latest work showing how breast cancer cells adapt to chemotherapy by activating the Wnt pathway and acquiring drug-tolerant persister cell features such as a diapause transcriptional signature and chemoresistance. @scil_leuven biorxiv.org/content/10.110…
Very happy to share our latest review @GeertLab, discussing recent advances in #bone cell #metabolism, now published in @NatureRevEndo! Interested in finding out why the #skeleton is such a metabolic powerhouse? Read it here: nature.com/articles/s4157…
🔬 Exciting opportunity alert! Join my new team as a Research Assistant and dive into investigating the role of citrate & SLC13A5 in bone mineralization & epilepsy. Ready to ignite new discoveries? Apply now! 🚀@washu_ortho_res @WashU_MRC
Grant application news day! Happy to share that our @FWOVlaanderen project on epigenetic in osteoarthritis will be funded. New questions to solve with @SilviaMonteag. Also happy for other SBE team @SCEBP_Lab to be successful in this round - @DevReg_KULeuven @KU_Leuven
Great news Indeed! Proud to work at KU Leuven!
Great news: #kuleuven rises 15 places in the QS World University Rankings, landing in 61st place, its best result to date🤩 #QWUR nieuws.kuleuven.be/en/content/202…
New review available! An overview of effector molecules, cells, and cytokines in both local and systemic OA-associated inflammation. tinyurl.com/37yvtxwd Thank you @AnaEscribano7 @AstridRoover @SilviaMonteag - a team effort
📢 PhD position available 📢 We have an exciting project for a motivated #PhD student to study how #metabolic alterations in skeletal progenitors cause #osteoporosis! More info 👇: kuleuven.be/personeel/jobs… Please share and RT! #research #bone @ECTS_science @AcademyEcts @ASBMR
Great day yesterday at the PhD defense of @AstridRoover, she did excellent!!! Thanks to the awesome jury members, our team (top video!) and everyone present!! @TissueHomandDis @DevReg_KULeuven
Big congratulations to our PhD student @AstridRoover for obtaining a junior @FWOVlaanderen postdoc fellowship!! @TissueHomandDis and I are very happy to continue working with you in the coming years @DevReg_KULeuven @KU_Leuven #proudsupervisors
📢 Check this interesting highlight @NatRevRheumatol of our lastest study on #epigenetics mechanisms and targets in #osteoarthritis ! 👌👌👩🏻🔬 @ReemAssi1 @TissueHomandDis @ChahrazadCHERI1 Research done @DevReg_KULeuven @KU_Leuven thanks to @FWOVlaanderen
New content online! Targeting KDM2/7 histone demethylases could protect against OA dlvr.it/SnqYyF
Registration and abstract submissions are now open for the Cutting Edge Osteoarthritis Meeting! #CE_OA23 @OACentreOxford
Check out our new review on intra-articular therapies for osteoarthritis just published in @DrugsJournal 💉 with @JolienQuintiens @TissueHomandDis @SilviaMonteag rdcu.be/c98ra
This paper on the regulation of key protective molecule ANP32A in #osteoarthritis identifies the hypoxia and Wnt signaling pathways as regulators of ANP32A expression, rendering them interesting therapeutic targets. @TissueHomandDis @SilviaMonteag bit.ly/3Ka20Ty
Very excited to present our latest findings on #epigenetics in #cartilage and #osteoarthritis, just out in @ARD_BMJ Hard 💪and fun🥳 team work, especially with @ChahrazadCHERI1 @ReemAssi1 and Rik Lories @TissueHomandDis at @DevReg_KULeuven. Check it out here!! 👇
Happy to share our new paper on #epigenetics in #osteoarthritis just published in @ardbmj with lead authors @ReemAssi1 @ChahrazadCHERI1 @TissueHomandDis @SilviaMonteag from @devreg @kuleuven in collaboration with @LUMC_Leiden tinyurl.com/2s47pcup (1/10)
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