Yves Clément 💻🧬🇺🇦🇪🇺
@TwelveSharp
Assistant prof at @univ_paris_cite & @stemdevevo team at @IJMonod. Comparative genomics and bioinformatics.
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I am hiring! - looking for a Staff Scientist to co-run my research group with me. Staff Scientist is a senior professional scientist role at EMBL. Please forward to people you might know who could be interested! embl.wd103.myworkdayjobs.com/en-US/EMBL/job…
How did animals repeatedly conquer land? 🌊➡️⛰️ We analysed ~1,000 gene repertoires (24M genes!) from all animal phyla to uncover how this happened. Work led by @gemmaeling & @klara_eleftheriadi, both first coauthors of this titanic effort! biorxiv.org/content/10.110…
A woman????
BREAKING NEWS The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”
BREAKING NEWS The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”
#Institutionnel 🧬 | En septembre 2025, le programme de recherche ATLASea a franchi la barre des 100 génomes marins séquencés ! #PEPR #France2030 ▶️ insb.cnrs.fr/fr/cnrsinfo/at…
La marque des grands : écrire au tableau sans regarder ce qu’on écrit. Je devrais faire ça, coder sans regarder ce que je tape
En alliant abstraction théorique et retombées concrètes, Stéphane Mallat, lauréat 2025 de la médaille d’or du CNRS, a marqué de son empreinte les mathématiques appliquées à l’informatique. Du format de compression d’images JPEG 2000 aux fondements ... lejournal.cnrs.fr/articles/steph…
#Communiqué 🗞️ La médaille d'or 2025 du CNRS est décernée à Stéphane Mallat, mondialement reconnu pour ses travaux autour des mathématiques appliquées au traitement du signal et à l’intelligence artificielle. 👏 👉 cnrs.fr/fr/presse/entr… #TalentsCNRS 🏅
📢 Happy to announce that Ensembl 115 and Ensembl Genomes 62 are out! This release features ~120000 new protein coding transcripts in human GRCh38, 2 new cattle, 7 new plants and 20 new metazoa! 🧬🐮 🫛🪲 Read more here ➡️ zurl.co/poyXM
Happy RNA Day to those who celebrate! 🧪 It’s AUG 1: the day we Met 🤓
Biological foundation models have hit a plateau. Scaling isn't working as expected. Foundational concepts from evolutionary biology could have predicted this: 🧵 research.arcadiascience.com/pub/idea-phylo… [1/9]
#TalentCNRS 🥉| Flora Jay, entre génomes synthétiques et récits évolutifs, reçoit la médaille de bronze du CNRS. ➡️ ins2i.cnrs.fr/fr/cnrsinfo/fl… 🤝 @LisnLab @CNRSIdFSud
Practically useful & biologically aligned benchmarks such as this one from @pkoo562 lab consistently show that all the overhyped annotation-agnostic DNA language models are actually terrible for transcriptional regulatory DNA in humans (mammals). 1/
*Easter egg alert* NOT in the published paper. We also benchmarked Evo 2 and while it did better than other gLMs (consistent that scale can improve gLMs), it still falls short of a basic CNN trained using one-hot sequences and far short of supervised SOTA x.com/pkoo562/status…
Our work on "Evaluating the representational power of pre-trained DNA language models for regulatory genomics" led by @AmberZqt with help from @NiraliSomia & @stevenyuyy is finally published in Genome Biology! Check it out! genomebiology.biomedcentral.com/articles/10.11…
Do current genomic language models (pre-trained on whole genomes) learn a foundational understanding of biology in the non-coding region of human genomes? A new evaluation led by @AmberZqt suggests not yet! 1/N paper: biorxiv.org/content/10.110…
🤣🤣🤣
Research papers from 14 institutions contained hidden prompts directing AI tools to give them good reviews. asia.nikkei.com/Business/Techn…
And there you go. "Journal plagued with problematic papers, likely from paper mills, pauses submissions" science.org/content/articl…
The human transcription factor occupancy landscape viewed using high-resolution in situ base-conversion strand-specific ... biorxiv.org/content/10.110… #biorxiv_genomic
REPORTAGE. Polychètes, échinodermes… Les scientifiques du programme Atlas Sea s'attaquent à la Méditerranée l.franceinfo.fr/ra5
A dozen years ago (!) we had a big job exploring 7 ant #genomes 🐜🧬alongside some other insects (Simola et al. 2013 genome.cshlp.org/content/23/8/1…) ... look how far the field has come - congrats GAGA on these great comparative analyses of 163 ant 🐜🧬 genomes! cell.com/cell/fulltext/…
The evolution of gene regulatory programs controlling gonadal development in primates biorxiv.org/content/10.110… #biorxiv_evobio
![Dumont_Lab's profile picture. [Ran by: Laura Blanco-Berdugo]
The Dumont lab focus on the mechanisms that generate genetic diversity through the lens of evolution.](https://pbs.twimg.com/profile_images/1529162226447294464/LrdHUvyk.jpg)
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