Yves Clément 💻🧬🇺🇦🇪🇺
@TwelveSharp
Assistant prof at @univ_paris_cite & @stemdevevo team at @IJMonod. Comparative genomics and bioinformatics.
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A big review of the evolution of bats: annualreviews.org/content/journa…
#ResultatScientifique 🔎 Certains gènes antiviraux humains partagent des défenses communes avec les bactéries, révélant une convergence évolutive surprenante 🧬 ✍️ @alexandre_lgrnd et Lucie Etienne 📕 Nature Ecology and Evolution insb.cnrs.fr/fr/cnrsinfo/de…
In light of James Watson's death, I post this article which clarifies Rosalind Franklin's contributions to the discovery of the structure of DNA. It is richer than the conventional narrative. nature.com/articles/d4158…
Applications open for the Workshop on Phylogenomics in beautiful Cesky Krumlov in January 2026. Best list of topics and faculty EVER!! More info here: evomics.org/2026-workshop-…
For over 20 years, the mouse model organism has helped scientists uncover the biology behind human health and disease. But the mouse reference genomes still have missing pieces. The first collection of telomere-to-telomere mouse genomes are available for two key mouse strains.
These two males belong to different species—but share the same mother. How? Why? To celebrate the print release of our last paper in this week’s @nature.com (issue 8084), here’s a thread summarizing the results. Why? Let’s dive in🧵👇nature.com/articles/s4158…
I am hiring! - looking for a Staff Scientist to co-run my research group with me. Staff Scientist is a senior professional scientist role at EMBL. Please forward to people you might know who could be interested! embl.wd103.myworkdayjobs.com/en-US/EMBL/job…
How did animals repeatedly conquer land? 🌊➡️⛰️ We analysed ~1,000 gene repertoires (24M genes!) from all animal phyla to uncover how this happened. Work led by @gemmaeling & @klara_eleftheriadi, both first coauthors of this titanic effort! biorxiv.org/content/10.110…
A woman????
BREAKING NEWS The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”
BREAKING NEWS The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”
#Institutionnel 🧬 | En septembre 2025, le programme de recherche ATLASea a franchi la barre des 100 génomes marins séquencés ! #PEPR #France2030 ▶️ insb.cnrs.fr/fr/cnrsinfo/at…
La marque des grands : écrire au tableau sans regarder ce qu’on écrit. Je devrais faire ça, coder sans regarder ce que je tape
En alliant abstraction théorique et retombées concrètes, Stéphane Mallat, lauréat 2025 de la médaille d’or du CNRS, a marqué de son empreinte les mathématiques appliquées à l’informatique. Du format de compression d’images JPEG 2000 aux fondements ... lejournal.cnrs.fr/articles/steph…
#Communiqué 🗞️ La médaille d'or 2025 du CNRS est décernée à Stéphane Mallat, mondialement reconnu pour ses travaux autour des mathématiques appliquées au traitement du signal et à l’intelligence artificielle. 👏 👉 cnrs.fr/fr/presse/entr… #TalentsCNRS 🏅
📢 Happy to announce that Ensembl 115 and Ensembl Genomes 62 are out! This release features ~120000 new protein coding transcripts in human GRCh38, 2 new cattle, 7 new plants and 20 new metazoa! 🧬🐮 🫛🪲 Read more here ➡️ zurl.co/poyXM
Happy RNA Day to those who celebrate! 🧪 It’s AUG 1: the day we Met 🤓
Biological foundation models have hit a plateau. Scaling isn't working as expected. Foundational concepts from evolutionary biology could have predicted this: 🧵 research.arcadiascience.com/pub/idea-phylo… [1/9]
#TalentCNRS 🥉| Flora Jay, entre génomes synthétiques et récits évolutifs, reçoit la médaille de bronze du CNRS. ➡️ ins2i.cnrs.fr/fr/cnrsinfo/fl… 🤝 @LisnLab @CNRSIdFSud
Practically useful & biologically aligned benchmarks such as this one from @pkoo562 lab consistently show that all the overhyped annotation-agnostic DNA language models are actually terrible for transcriptional regulatory DNA in humans (mammals). 1/
*Easter egg alert* NOT in the published paper. We also benchmarked Evo 2 and while it did better than other gLMs (consistent that scale can improve gLMs), it still falls short of a basic CNN trained using one-hot sequences and far short of supervised SOTA x.com/pkoo562/status…
Our work on "Evaluating the representational power of pre-trained DNA language models for regulatory genomics" led by @AmberZqt with help from @NiraliSomia & @stevenyuyy is finally published in Genome Biology! Check it out! genomebiology.biomedcentral.com/articles/10.11…
Do current genomic language models (pre-trained on whole genomes) learn a foundational understanding of biology in the non-coding region of human genomes? A new evaluation led by @AmberZqt suggests not yet! 1/N paper: biorxiv.org/content/10.110…
![Dumont_Lab's profile picture. [Ran by: Laura Blanco-Berdugo]
The Dumont lab focus on the mechanisms that generate genetic diversity through the lens of evolution.](https://pbs.twimg.com/profile_images/1529162226447294464/LrdHUvyk.jpg)
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