FlyBottleEscape's profile picture. Assistant Professor @Penn • Dept Psychiatry + Dept Neuroscience + Dept Anesthesiology | Pain • Placebo • Poppies • Psychedelics

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@FlyBottleEscape

Assistant Professor @Penn • Dept Psychiatry + Dept Neuroscience + Dept Anesthesiology | Pain • Placebo • Poppies • Psychedelics

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⚡️🧠A nociceptive amygdala-striatal pathway modulating affective-motivational pain Now published on the cover of @ScienceAdvances !!! Improved with projection-specific, pain-active intersectional chemogenetic pain behavior Check it out 👇 science.org/doi/10.1126/sc…

FlyBottleEscape's tweet image. ⚡️🧠A nociceptive amygdala-striatal pathway modulating affective-motivational pain

Now published on the cover of @ScienceAdvances !!!

Improved with projection-specific, pain-active intersectional chemogenetic pain behavior

Check it out 👇
science.org/doi/10.1126/sc…

⚡️🧠Thrilled to share our new preprint on pain-related valence cell-types + circuits — A nociceptive amygdala-striatal pathway for chronic pain aversion Check out the stellar work of Jessica Wojick, in a co-senior collab with @KorbLab biorxiv.org/content/10.110… THREAD 1/13



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Can only meat machines be conscious? Opinion by Ned Block (@De_dicto) Free access before Nov 26: tinyurl.com/yvurvp2p

TrendsCognSci's tweet image. Can only meat machines be conscious?

Opinion by Ned Block (@De_dicto)
Free access before Nov 26: tinyurl.com/yvurvp2p

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🇵🇷 La Dra. Yarimar Carrasquillo, de Puerto Rico al NIH, cambió nuestra forma de entender el dolor. Su historia es un ejemplo de curiosidad y resiliencia en la ciencia. Descubre cómo lo logró: storiesofwin.org/en-espanol/202… #MujeresEnCiencia #Neurociencia #CienciaLatina #LatinasInStem


been writing all my grants this cycle with this amazing score on a loop … with some aphex twin SAW 1

Trent Reznor and Atticus Ross' score for The Social Network turns 15 today. Revisit our Sunday Review of the groundbreaking collaboration here: pitchfork.visitlink.me/My7FyZ

pitchfork's tweet image. Trent Reznor and Atticus Ross' score for The Social Network turns 15 today. Revisit our Sunday Review of the groundbreaking collaboration here: pitchfork.visitlink.me/My7FyZ


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We are excited to share our latest work in @ScienceMagazine studying cooperative behavior in both biological and artificial intelligence systems — fantastic work by @JanineJiang22, Linfan Gu, and wonderful collaboration with @JonathanCKao! science.org/doi/10.1126/sc…

TheHongLab's tweet image. We are excited to share our latest work in @ScienceMagazine studying cooperative behavior in both biological and artificial intelligence systems — fantastic work by @JanineJiang22, Linfan Gu, and wonderful collaboration with @JonathanCKao! science.org/doi/10.1126/sc…

im gonna have a panic attack

FlyBottleEscape's tweet image. im gonna have a panic attack

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The forebrain circuits that regulate pain modulatory circuits during hyperalgesia are unknown. @LewisCrawford63 et al. identify forebrain activity and forebrain-brainstem connectivity that underpins nocebo hyperalgesia. Learn more in #PAIN bit.ly/46MK8Ki

PAINthejournal's tweet image. The forebrain circuits that regulate pain modulatory circuits during hyperalgesia are unknown. @LewisCrawford63 et al. identify forebrain activity and forebrain-brainstem connectivity that underpins nocebo hyperalgesia. Learn more in #PAIN bit.ly/46MK8Ki

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become my colleague at penn bioengineering: apply.interfolio.com/173716


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In what may be one of Earth’s craziest forms of mimicry, researchers in 2023 reported a species of rove beetle that grows a termite puppet on its back to fool real termites into feeding it. Learn more: scim.ag/48aDC0w #ScienceMagArchives

NewsfromScience's tweet image. In what may be one of Earth’s craziest forms of mimicry, researchers in 2023 reported a species of rove beetle that grows a termite puppet on its back to fool real termites into feeding it.

Learn more: scim.ag/48aDC0w #ScienceMagArchives

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Curious about why emotions are so difficult to understand? This debate about how to define them is insightful. Wrapping my head around these issues was both mind blowing and clarifying for me. I'm grateful for all the experts who chimed in!

In this "Big picture" debate, @NicoleCRust explores the controversy around the terminology used to characterize emotions—and invites 13 experts to chime in. thetransmitter.org/the-big-pictur…



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What can *genetic insensitivity to opioids* teach us about endogenous opioid function in humans? Fully funded position in Oslo (PhD student or postdoc) Please RT Interested in pain, mu/kappa opioids, behavioural genetics, RCTs, or related? Apply here: 2411.webcruiter.no/Main2/Recruit/…


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Excited to share our new methods paper, spearheaded by the incredible @JordanGrammer (NSF GRFP graduate student in the lab)! An integrative assay for measuring social aversion and motivation in freely behaving mice: Cell Reports Methods cell.com/cell-reports-m…


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This is a cool paper, but not sure if the findings are impressive enough to be too excited about. The authors used a GWAS of a pain phenotype and decided to study a gene (SLC45A4) at a specific locus in detail. The genetic association itself is robust, replicates across…

A massive genetic study in @Nature just identified why chronic pain hits some people harder than others. They discovered the first neuronal “pain transporter” - and it could unlock entirely new ways to treat pain. 🧵

DrDominicNg's tweet image. A massive genetic study in @Nature just identified why chronic pain hits some people harder than others.

They discovered the first neuronal “pain transporter” - and it could unlock entirely new ways to treat pain. 🧵


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Congrats to @ManwalHarb and the rest of the team. Our paper on targeting spatially-defined projections with AAV9.retro with focused ultrasound is now published. We quantified transduction and found that ultrasound can match efficiency of invasive delivery aiche.onlinelibrary.wiley.com/doi/10.1002/bt…


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New paper from the lab with @andrewlutas. Work of the amazing Claire Gao. Important read exploring mechanistic insights as to why semaglutide may work better for some versus others. Building on all the amazing research that has been done over the years. biorxiv.org/content/10.110…


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Optimized DBS for ACC inhibition produces antidepressant-like effects in mice cell.com/neuron/fulltex…


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