⚡️GREG_CORDER⚡️
@FlyBottleEscape
Assistant Professor @Penn • Dept Psychiatry + Dept Neuroscience + Dept Anesthesiology | Pain • Placebo • Poppies • Psychedelics
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⚡️🧠A nociceptive amygdala-striatal pathway modulating affective-motivational pain Now published on the cover of @ScienceAdvances !!! Improved with projection-specific, pain-active intersectional chemogenetic pain behavior Check it out 👇 science.org/doi/10.1126/sc…
⚡️🧠Thrilled to share our new preprint on pain-related valence cell-types + circuits — A nociceptive amygdala-striatal pathway for chronic pain aversion Check out the stellar work of Jessica Wojick, in a co-senior collab with @KorbLab biorxiv.org/content/10.110… THREAD 1/13
Cobain was wrong ... good little book to check out for my pain biology friends: amazon.com/Fish-Feel-Pain… here's a lecture from the late Dr Victoria Braithwaite youtu.be/4wjXXvMUU6s?si…
just some numbers: - i'm submitting close to 100 rec letters for my studentss grad school apps today - our penn neuro grad program is on track for well over 1000 apps by the dec 1 deadline
#NGG is proud to present our next Thesis Defense given by Sophie Rogers of the Corder Lab @FlyBottleEscape! Please join us in person or virtually (DM us for the link) on 12/11. Best of luck, Sophie! #PhAlmostDone 🥳
🙌🏼 finally chased down a 15-year grail for me: @KiDCuDi x @SurfacetoAir collab jacket ✨ **humming** hmmmmmm yeah hmmmmhMHmmmm
Fix your hearts or die … Locked in for 18+ hours of Twin Peaks: The Return in theater @phillyfilmsoc ☕️ 🌲 🦉🥧
What if we could watch AND control thousands of individual neurons in behaving mice—with stable access over months? 🧠⚡ Our new preprint introduces transgenic all-optical tools that make this possible - and a resulting surprising discovery! 🔭💡 biorxiv.org/content/10.110… 1/13 🧵
No, look at *this* distribution of z-values from medical research! (329,601 z-values from Cochrane database)
Excited to share @Nature: How does naloxone (Narcan) stop an opioid overdose? We determined the first GDP-bound μ-opioid receptor–G protein (wt) structures and found naloxone traps a novel "latent” state, preventing GDP release and G protein activation. 🧵 nature.com/articles/s4158…
Excited to share our @npp_journal review on kappa opioid receptors. @ZFarahbakhsh & I cover the canonical and dissenting viewpoints in parallel. In particular, we push back on the idea that the essential function of the kappa system is to encode aversion: nature.com/articles/s4138…
dead, im giving a virtual visit at a neuo dept and they AI'd my headshot to send around to people, nooooo 😭
Have you been looking for peer-reviewed evidence of attention’s role in pain perception? Check out Zhi et al.’s article in Annals of @NYASciences, a #PRF #PapersoftheWeek pick from @Alex_Chesler bit.ly/4oHeovR
Exactly one year later … happy to say we successfully flipped this decision 🎃
😱 Just got 🪓 by a Reviewer 3 who reviewed our 8-month old preprint and NOT the manuscript we submitted to the journal … Unreal… ALL of their comments were addressed in actual thing we submitted 💀
Ascending nociceptive pathways drive rapid escape and sustained avoidance in adult Drosophila biorxiv.org/content/10.110… #biorxiv_neursci
Lavender 🌸👾✌🏼
Hooray!! The first major product from the lab is out today @Nature. Small molecules that bind the GPCR-transducer interface change G protein subtype selectivity in predictable ways, enabling rational drug design.💥 Check it out! 👉nature.com/articles/s4158… 🧵👇
We are excited to share our latest review article published in Nature Reviews Neuroscience! It was a pleasure to collaborate with fantastic colleagues @Victor_Mathis_ and @EhrlichAliza We discuss the neural circuits and signaling pathways driving OUD. rdcu.be/eMVT8
Differential encoding of noxious heat and self-reported pain along corticospinal networks: a simultaneous spinal cord-brain fMRI study biorxiv.org/content/10.110… #biorxiv_neursci
Today was my second best film experience ever seeing a 35-mm print of Mullholland Drive in a packed theater
Seeing the 70mm at the Grand Lake Theater in Oakland was easily THE best film experience ever for me
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