Zhang Lab@ISM
@ZhangLabISM
Big fan of T cell biology. Enthusiastic for developing next-generation therapeutic strategies against cancer.
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Very glad to share our recent story about fostering DC-T cell crosstalk for anti-tumor immunity
Engineered T cells stimulate dendritic cell recruitment and antigen spreading for potent anti-tumor immunity @CellRepMed cell.com/cell-reports-m… 🇨🇳
Thanks to all for your great efforts
Online now: Succinate preserves CD8+ T cell fitness to augment antitumor immunity dlvr.it/TMV7X7
Malonate promotes CD8+ T cell memory formation via protein malonylation nature.com/articles/s4142…
DCs are key for mounting effective antitumor immunity
New in The Innovation Medicine! Dendritic cells instruct T cell anti-tumor immunity and immunotherapy response. In this review, Xiao et al. discuss recent advancements in our understanding of DC biology under homeostatic conditions and within the tumor microenvironment with a…
🔥@trendscancer🆙 ✅Turning cold into hot: emerging strategies to fire up the tumor microenvironment 🎯Summary of the intrinsic, extrinsic, and systemic factors developing ‘cold’ tumors 👥Dr. Kaili Ma #LCSM @OncoAlert #ICI cell.com/trends/cancer/…
Cystine deprivation triggers CD36-mediated ferroptosis and dysfunction of tumor infiltrating CD8+ T cells dlvr.it/T2nRSF
nature.com
Cystine deprivation triggers CD36-mediated ferroptosis and dysfunction of tumor infiltrating CD8+ T...
Cell Death & Disease - Cystine deprivation triggers CD36-mediated ferroptosis and dysfunction of tumor infiltrating CD8+ T cells
Big Congratulation! @UtzschneiderD!
Boosting exhausted T cells: Dr Daniel Utzschneider has identified how T cells can become exhausted from battling cancer, reducing the effectiveness of immunotherapy. He will use his CSL Centenary Fellowship to study these cells. @TheDohertyInst bit.ly/3tlcYzF
An excellent collection of reviews covering anti-tumor immune cycle.
Special issue on "The cancer-immunity cycle," a concept first introduced by Mellman & Chen in 2013 that provided a framework to understand anti-cancer immunity | Seven articles discussing progress & advances in the field & highlighting key challenges #cancerimmunitycycle…
Our study about ERAD and CD8+T cell survival and homeostasis was just out at Cellular & Molecular Immunology. Congratulations to all the authors and collaborators.
SEL1L preserves CD8+ T-cell survival and homeostasis by fine-tuning PERK signaling and the IL-15 receptor-mediated mTORC1 axis dlvr.it/SvtMz5
nature.com
SEL1L preserves CD8+ T-cell survival and homeostasis by fine-tuning PERK signaling and the IL-15...
Cellular & Molecular Immunology - SEL1L preserves CD8+ T-cell survival and homeostasis by fine-tuning PERK signaling and the IL-15 receptor-mediated mTORC1 axis
Online now! Extracellular acidosis restricts one-carbon metabolism and preserves T cell stemness dlvr.it/ShgZQ4
Thank you Pedro for your great support during my stay in the lab, which is much appreciated. You are too young to be retired.
The stage of most honor symposiums elicit admiration for a scientist's life work. Pedro Romero's at @unil @CHUVLausanne @Ludwig_Cancer was no exception. Equally carried by the testimonies of speakers & students today was his vibrant humanity, clearly. Thank you, Pedro...
It was nice to summarize how metabolic programs tailor T cell immunity in the context of infection, cancer and aging, together with @PCHo_Lab and @sofie_h_moller, @Cell_Metabolism. Great teamwork!
Our new review in @Cell_Metabolism . It is a fun process to discuss new angles for this work with @sofie_h_moller and @ZhangLabISM ! @OncoUNILCHUV @Ludwig_Cancer authors.elsevier.com/a/1egCY_ZG9ULj…
Read our new study synthesized chemically recyclable solid polyesters with a high #CO2 content, high MW, and promising adhesive properties. This work provides a brand-new avenue to potential large-scale utilization of CO2 as a main #chemical feedstock. doi.org/10.1016/j.xinn…
A must read!
⭐️SO excited to finally be able to share the January issue of @CD_AACR, which includes "Hallmarks of Cancer: New Dimensions" by #DougHanahan!! cancerdiscovery.aacrjournals.org/content/12/1/31
It was nice to write with @PCHo_Lab
This #CIRreview discusses the role of #AminoAcids in #Tcell differentiation and function and in #AntitumorResponses, as well as how #metabolism can be targeted using immunotherapy. bit.ly/3oAtvep @PCHo_Lab
Rapid and accurate identification of SARS-CoV-2 variants containing E4... sciencedirect.com/science/articl…
Meet #JITC Editor-in-Chief Pedro J. Romero and other members of the JITC team at the SITC booth 12:45-1:15pm EST today. We would love to hear from you about your research and talk about ways to get engaged in the journal! #SITC21 @sitcancer
“Can machines think?”“Can AI do fundamental research?”“How does AI accelerate fundamental research?” Artificial Intelligence: A Powerful Paradigm for Scientific Research sciencedirect.com/science/articl…
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