David A Knowles (@davidaknowles.bsky.social)
@david_a_knowles
machine learning and functional genomics at @Columbia and @nygenome. he/him/his. @[email protected] @davidaknowles.bsky.social
قد يعجبك
Free in-person registration is open for #MLCB2025! Sept 10-11 at @nygenome and online at youtube.com/@mlcbconf. Paper/abstract deadline is June 1, more deets including our fantastic invited speaker lineup at mlcb.org! Please RP.
📣New from @david_a_knowles & co! 📄Leveraging functional annotations to map rare variants associated with #Alzheimer disease with gruyere cell.com/ajhg/abstract/…
*Every single* cure for a disease ultimately flowed from basic exploratory research. Stopping basic research is like stopping the mountain rains and expecting rivers of cures to still flow. Examples: 1) studying saliva of Gila monster -> GLP1's 2) studying funghi -> first…
As a taxpayer (irrespective of whether you’re a scientist) would you would be in favor of more of the @NIH budget going to fund efforts to solve specific diseases at the expense of basic exploratory research? Which diseases?
explainer for the tech bros. 60% is added on top of direct cost (and equipment are not included). So for every dollar that goes to a scientist, roughly $0.80 is allowable. Then you add 60% facilities/admin costs on top ($0.48). Uni’s final cut is $0.48/$1.48 =0.324 of the grant
Your math is wrong dude. Let me get this straight. All this time you thought a that an indirect cost rate of 60% meant that Universities took 60% of the grant? 🤦♂️
Ok that's it I'm done here. I'll leave this account up to avoid it being eventually commandeered. but will not be posting/interacting.
#MLCB2025 will be Sept 10-11 at @nygenome in NYC! Paper deadline June 1st & in-person registration will open in May. Join our mailing list groups.google.com/g/mlcb/ for future announcements. More details at mlcb.github.io. Please RT!
There are 10 days left to submit abstracts to ProbGen meetings.cshl.edu/meetings.aspx?…! Fantastic line-up of speakers and topics.
Please could some @PyroAi folks (@ftzo @Tkaraletsos @nmancuso_) give me some insight on what I'm doing wrong here? forum.pyro.ai/t/error-with-e…
Our first foray into (noncoding) rare variant association testing! gruyere learns functional annotation importance & finds associations missed by existing methods. @_anjalidas did a fantastic job with model assessment & scaling! Joint w @towfiqueRaj medrxiv.org/content/10.110…
The fantastic Machine Learning in CompBio #MLCB2024 papers are up at proceedings.mlr.press/v261/ (thanks @lawrennd !) Reminder that all the talks are available on our yt channel youtube.com/@mlcbconf. Please RT!
The fantastic #MLCB2024 talks, spotlights, panel & keynotes are now up on our Youtube channel at youtube.com/watch?v=tWzIK1…. Please RT!
youtube.com
YouTube
MLCB 2024: Introduction–Sara Mostafavi (Paul G. Allen School of...
#MLCB2024 is live at youtube.com/live/GflTIcI5i… ! First up @zhou_jian on interpretable DL for transcription initiation.
youtube.com
YouTube
2024 Machine Learning in Computational Biology (MLCB) Conference—Day 1
Two @TroyanskayaLab alums — @zhou_jian & @ChikinaLab — giving keynotes at #MLCB2024! Jian now talking about sequence basis of transcription initiation in the human genome. Tomorrow, Maria is talking about biophysically interpretable sequence to function models.
#MLCB2024 kicks off in 22h (9am PST) with keynote from @zhou_jian on DL for transcriptional initiation! Full schedule at mlcb.github.io and public livestream at youtube.com/live/reqWvNOKl…. Please RT!
youtube.com
YouTube
2024 Machine Learning in Computational Biology (MLCB) Conference—Day 1
#MLCB2024 kicks off in 22h (9am PST) with keynote from @zhou_jian on DL for transcriptional initiation! Full schedule at mlcb.github.io and public livestream at youtube.com/live/reqWvNOKl…. Please RT!
youtube.com
YouTube
2024 Machine Learning in Computational Biology (MLCB) Conference—Day 1
Looking forward to #MLCB2024 later this week! Really happy to see the wide variety of work being done. Sometimes, in the past, it seems like the field converged on the same set of problems... Sad that I won't be able to be there in person this year. :(
#MLCB2024 will be streamed live from YouTube this week (Thursday and Friday). Get the link from here: mlcb.github.io
📢I am elated to share that I will join the Center for Neural Science & Dept. of Psychology at NYU as an Assistant Professor in Sept 2025! My lab will use the remarkable food-caching behavior and active vision of chickadees to study the neural basis of episodic memory 🕊️🧠👀🏙️✨
#MLCB2024 deadline extended to June 17!!
MLCB2024 abstract/paper submission deadline is coming up (June 15). mlcb.github.io Also check out the list of fantastic keynote speakers: Maria Chikina (@ChikinaLab), Ava Amini (@avapamini), Jian Zhou (@zhou_jian), Nilah Ioannidis, Sergey Ovchinnikov (@sokrypton)
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