
David Sharp
@davidjsharp2015
Professor at Albert Einstein College of Medicine. Co-Founder and Chief Scientific Officer of MicroCures
내가 좋아할 만한 콘텐츠
My presentation at #OIS XIV describing MicroCures and our ongoing journey from compelling animal data to clinical trials. Case Study 1: Crossing the Valley of Death youtu.be/GHVUvr9ygNA?si… via @YouTube
youtube.com
YouTube
Case Study 1: Crossing the Valley of Death
Fantastic time at #OIS XIV in San Diego, and a thrill to commingle with the many innovators and thought leaders in ophthalmology.



Excited to be presenting at the upcoming RNAi-Based Therapeutics Summit in Boston. If you're interested in RNAi therapeutics, you can view the agenda and secure a seat at the Summit here ter.li/6aa561

Please check out our poster #1426 today by Shira Glushakow-Smith @theHematoPoet on epigenetic resistance mechanisms to PI3K inhibition in AML! @Einstein_SCI @EinsteinPhD
At #ASH23, @EinsteinCellBio's very own @TheHematoPoet is presenting data on her thesis research focused on delineating and targeting epigenetic resistance mechanisms to PI3K inhibition in LSCs. Check out her poster #1426 during the Saturday night poster session.
A nice write-up about our recent work on nerve regeneration. A collaborative effort with Kelvin Davies' lab @EinsteinMed and a technology that may be expanded to various forms of PNS injury. Also being developed for commercialization @MicroCures
Einstein Researchers: Preserving Erectile Function Following #ProstateCancer Surgery | Learn more at bit.ly/46NdIws #ErectileDisfunction #NIH

“This week, a new group of students is beginning its journey at Einstein, and this has prompted some reflection on my own first weeks.” Karishma Smart, Ph.D., class of '23, writes of what #PHD students should focus during graduate #orientation at bit.ly/43PDKwK. #PHDLife

Brilliant scientist, amazing person person
Watch as @therealksmart, who graduated Wednesday, thanks her mentor, @davidjsharp2015, for pushing her to be an independent scientist and supporting her growth in confidence. Dr. Sharp also pays tribute to their mentor-mentee relationship. #PHD #mentoring #EinsteinClassof2023
For eight years, Karishma Smart, Ph.D., experienced lab life ups and downs as a graduate student at Einstein. While looking forward to graduation Wednesday, she has mixed emotions about leaving the bench behind. Read more: bit.ly/3MRXeM8 #EinsteinClassof2023 #PhdLife

Congrats to my student Karishma Smart @therealksmart (soon to be Dr. Smart) for publishing her brilliant work cell.com/biophysj/fullt…
cell.com
Fidgetin-like 2 depletion enhances cell migration by regulating GEF-H1, RhoA, and FAK
The microtubule (MT) cytoskeleton and its dynamics play an important role in cell migration. Depletion of the microtubule-severing enzyme Fidgetin-like 2 (FL2), a regulator of MT dynamics at the...
My wife just landed at Chicago O'Hare to this sight off the runway. Whats going on? @fly2ohare @AmericanAir

New paper alert!🚨 So happy to see our work out in @CellStemCell today! Instead of a tweetorial, I would like to take this opportunity to highlight the amazing contributions of my co-authors in this thread 🧵 You can read about the work here👇🏻 news.mit.edu/2022/microglia…
Our study to understand how kinesin-8 can have both motility and microtubule depolymerization activities came out! 7 #CryoEM structures @SosaLab4. Data collected @SEMC_NYSBC. Collaboration with @AllinghamJohn lab, biochem & X-ray structure by Byron Hunter. nature.com/articles/s4146…
If you're interested to learn more about our work on spinal cord injury, and tissue regen/repair more generally, I'll be speaking at the Miami Project this coming Wednesday at noon ET. ZOOM accessible to all and login info in announcement below themiamiproject.org/event/gail-f-b…
nature.com/articles/s4146… Since preprint, the #CryoEM datasets were further processed with #Relion to separate kinesin dimers or coexisting conformations on microtubules. 3 of 20 structures (2.7-3.9 Å) below. @SosaLab4 @SEMC_NYSBC #kinesins #microtubules #biophysics #cellbiology

Fidgetin-like 2 negatively regulates axonal growth and can be targeted to promote functional nerve regeneration: buff.ly/2QdcPva @EinsteinMed #Neuroscience #ReproductiveBiology
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