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So very happy to share our preprint for the main work of both our PhDs ! Check out Rene's thread to learn about the tools we developed for #chloroplast engineering and how we use them to test a photorespiratory bypass in #Chlamydomonas !!
Very excited to share the preprint of a big chapter of my PhD, where I am corresponding & shared first author (together with @gitanguy) about advancing #chloroplast #synbio through high-throughput plastome engineering of #Chlamydomonas: Below in a 🧵: biorxiv.org/content/10.110…
New in Nature Communications: Our study uncovers how green algae coordinate the CO₂-concentrating mechanism and photorespiration during low CO₂ acclimation. This has implications for oceanic carbon cycling. 1/4 nature.com/articles/s4146… #Algae #Photosynthesis #ClimateScience

Happy to share our story on evolution of protein quaternary structure! We discover an astounding variation in assembly across evolutionary timescales contrasted by strong functional conservation suggesting a significant role of non-adaptive processes nature.com/articles/s4146… 👇🧵
Lets talk about #acetyl-CoA! As central molecule in C1 metabolism, the efficiency of its assimilation determines yields. Read below about our Lcm as novel activity in the shortest O2 tolerant route to make pyruvate from acetyl-CoA while fixing #CO2! nature.com/articles/s4146…

Want to become my colleague? Come to Marburg, come to the Microcosm Earth Center, become a research group leader! Application Deadline December 15th 2024. stellenangebote.uni-marburg.de/jobposting/e6e…
🚨 We're hiring!🚨 Paris Biofoundry is looking for an Application Engineer in Biological Analyses by Mass Spectrometry.🧬 📅 Start: Feb 1, 2025 📍 Location: Paris 🧪 Requirements: MSc in Biochem/Analytical Chemistry, 1-4 yrs experience Apply now ! 🔗 parisbiofoundry.org/our-job-opport…

Unique biogenesis and kinetics of hornwort Rubiscos revealed by synthetic biology systems: Molecular Plant cell.com/molecular-plan… @MPlantPCom
Excited to share our latest preprint! Proteomic analysis of the pyrenoid-traversing membranes of Chlamydomonas reinhardtii reveals novel components biorxiv.org/content/10.110…

Thrilled to share our latest preprint on how Chlamy acclimates to light stress under day-night cycles! We provide a genome-wide view of the central dogma, correlate changes in thylakoid membranes with the lipidome, track photodamage, quenching, and more. doi.org/10.1101/2024.1…
Too dim, too bright, and just right: Systems analysis of the Chlamydomonas diurnal program upon acclimation to light stress and limitation biorxiv.org/content/10.110…
It was an amazing experience to attend the Grand Jamboree and see all the incredible ideas! We are thrilled to have won the Grand Prize. We would like to thank all the sponsors, supervisors, PIs and supporters who made this possible. Words cannot express our gratitude! @iGEM


Congratulations to @igemmarburg and iGEM Heidelberg for winning the Grand Prize🥳!


Finally, decided to post my lecture slides online. Hoping someone will find them useful🙂 manishkushwaha.net/teaching/

Novel enzyme starts with promiscuity. Excited to share our study that shows how #evolution recruits a single enzyme for multiple purposes, showcasing the plasticity and flexibility of #metabolism. Huge thanks to my colleagues at @erblabs & @mpi_marburg! rdcu.be/dXaqU
Excited to finally making the first steps turning our DynaPore project into an actual technology! Please, support us by casting a vote for team DynaPore 🦖
From #research to #application: Our DynaPore team, @ScottAScholz, @bobelly_, @mmMarkus_Meier and Owen Jarman from @erblabs are competing at #HIWettbewerb start-up competition. 𝗩𝗼𝘁𝗲 for team DynaPore until Nov 7th, to support them in reaching the final: hessen-ideen.de/ideen/alumni/d…
From #research to #application: Our DynaPore team, @ScottAScholz, @bobelly_, @mmMarkus_Meier and Owen Jarman from @erblabs are competing at #HIWettbewerb start-up competition. 𝗩𝗼𝘁𝗲 for team DynaPore until Nov 7th, to support them in reaching the final: hessen-ideen.de/ideen/alumni/d…
I am so happy to be a part of the Hessen Ideas competition with our amazing team from the MPI-TM! Please take a moment to vote for our Project DynaPore 🦖 All links and some pretty team pictures in the thread below ;) #ideenwettbewerb #HIWettbewerb
From #research to #application: Our DynaPore team, @ScottAScholz, @bobelly_, @mmMarkus_Meier and Owen Jarman from @erblabs are competing at #HIWettbewerb start-up competition. 𝗩𝗼𝘁𝗲 for team DynaPore until Nov 7th, to support them in reaching the final: hessen-ideen.de/ideen/alumni/d…
Our paper on continuous mutagenesis in living cells using HACE is now out in @ScienceMagazine! We now demonstrate that HACE continuously generates mutations over a 10-day period and enables targeting using dCas9 without introducing DNA nicks. science.org/doi/10.1126/sc…
I am thrilled to present the Paris Biofoundry to the World. A distributed Biofoundry for high-throughout engineering of bacteria, yeast, microalgae, mammalian cells, and Cell-free systems. #biofoundry #Synbio
🧬Excited to introduce the @ParisBiofoundry uniting @Sorbonne_Univ_, @Genopole, @institut_curie and @INRAE_MICALIS. 🌍🔬 Our goal? Accelerating #innovation in #health, #sustainability, and #biotech through #bioengineering and #robotics. Stay tuned !👉 parisbiofoundry.org
parisbiofoundry.org
Accueil - Paris Biofoundry
The Paris Biofoundry The Paris Biofoundry is a pioneering research platform that unites the expertise and cutting-edge technology of several prestigious institutions in the Île-de-France region,...
🧬Excited to introduce the @ParisBiofoundry uniting @Sorbonne_Univ_, @Genopole, @institut_curie and @INRAE_MICALIS. 🌍🔬 Our goal? Accelerating #innovation in #health, #sustainability, and #biotech through #bioengineering and #robotics. Stay tuned !👉 parisbiofoundry.org
parisbiofoundry.org
Accueil - Paris Biofoundry
The Paris Biofoundry The Paris Biofoundry is a pioneering research platform that unites the expertise and cutting-edge technology of several prestigious institutions in the Île-de-France region,...
Congrats @james_r_barrett & co! My fave story this year: delving into nature's different approaches to condensing Rubisco into a pyrenoid 🤩 Same mechanism, different execution - and it works in land plants!! Huge implications for crop engineering nature.com/articles/s4147…
nature.com
A promiscuous mechanism to phase separate eukaryotic carbon fixation in the green lineage
Nature Plants - Barrett et al. identify a key Rubisco phase-separating protein in the CO2-fixing pyrenoid of Chlorella algae. This protein’s broad promiscuity for green lineage Rubiscos may...
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