Manish Kushwaha @manishmicrobe.bsky.social
@manishmicrobe
Synthetic Biology, Biological Computing, Bioengineering @INRAE_Micalis @INRAE_France @AgroParisTech @UnivParisSaclay. Views are my own.
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Pleased to share that our review on 'Reconstituting alternative life using the test-bed of cell-free systems' is now out in the Phil Trans B special issue on 'Origins of life'. royalsocietypublishing.org/doi/10.1098/rs… Co-authors Maud Hofmann, @FaroukAbdo_ , and @O_Borkowski
A tool for modeling gene regulatory networks (GRN_modeler) and its applications to synthetic biology doi.org/10.1038/s44320…
Sometimes “failures” spark new designs: a terminator leak inspired a feedback+feedforward controller with one promoter flip for tunable resource decoupling. Now online in NAR — congrats our PhD student Rixin Zhang! academic.oup.com/nar/article/53…
Overflow metabolism in bacterial, yeast, and mammalian cells: different names, same game doi.org/10.1038/s44320…
Applications to PhD scholarships in our Dept will open soon. Check it here if you want to join our group and our networks @IC_CSynBio @BezosCentre @EEBioPG : imperial.ac.uk/engineering/de…
New publication out today in @natBME 🎉led by @zsinger JPabon demonstrating engineered bacteria launch and control a virus. A very cool cooperative microbial strategy for cancer therapy. Congrats to all! in collab with @RiceLaboratory nature.com/articles/s4155…
The Santa Fe Institute is now accepting applications for the 2026 Complexity Postdoctoral Fellowships! Complexity fellows contribute to SFI’s research and collaborate with leading researchers worldwide. If you recently completed your PhD in any scientific discipline and are…
Distributed systems is the most fun field of computer science because of the stories behind each concept. That's why I'm launching Distributed Systems Made Simple, a YouTube channel to tell these stories in a fun way while diving deep into the "why". youtube.com/@DSMadeSimple
After a long sleep, environmental remediation with live biologics is back to the mainstream R&D agenda at this side of the pond. Wanna join an EU-wide on line conversation with bioremediation stakeholders this Nov 10? Express interest and register here 👉 forms.cloud.microsoft/e/b7xVz7dJcu
We're hiring for 2 postdocs to work in our lab in London on the newly announced Wellcome Trust SynHG project. If you know people looking to work on big-scale ambitious science like this, please RT and share this with them. Apply by 7/20, interviews in Aug. imperial.ac.uk/jobs/search-jo…
Please RT and share! We have up to two PhD positions available in my group for entry in fall 2026, applications expected in fall 2025. DM me if interested!
Our very own @O_Borkowski @INRAE_MICALIS talks about machine learning to maximize RNA production in CFS at #SEED2025
From the RBS calculator to the Genetic Systems Calculator, @hsalis lab brings us all the cool tools for biological engineering. #SEED2025
Two days of excellent discussions with @ceronifranci and @LucaCiandrini. So great to have them visit.
Fantastic talks on resource competition in cells by @ceronifranci and @LucaCiandrini !!!! It was a pleasure to have them at @INRAE_MICALIS and to exchange ideas on their past work and exciting new projects.
Synthetic biology could enable new types of programmable therapeutics. Our new preprint introduces synthetic protein circuits that selectively trigger cell death in Ras-mutant cancer cells, with interesting advantages compared to existing approaches. biorxiv.org/content/10.110…
15+ open positions are up on our #SynBio Job Board for early, mid-career and late-career professionals! Discover the jobs here: community.igem.org/job-board
Multiobjective learning and design of bacteriophage specificity biorxiv.org/content/10.110…
We are hiring for a funded PhD in design of cross- and multi-species genetic circuits. #PhD #synbio #crossspecies #multispecies #biocomputing #circuits #pathways @INRAE_MICALIS @UnivParisSaclay Details here: cellularcomputing.team/joinus/
“Using LySE, we evolved [..] a 50.9% increase in end-point biomass of a bacterial strain that utilizes the PET monomer, ethylene glycol, as its sole carbon source.” —> nice work
Accelerated evolution of whole gene clusters by an engineered lytic phage system in E. coli biorxiv.org/content/10.110… #biorxiv_synbio
New paper from the lab! Thanks to @BBSRC @MIBTP_BBSRC @WarwickLifeSci for the funding! Great work from Michael Tadesse and my two MBio students Nala and Martha. Thanks to @AlbertiFabrizio for the great collaboration!! @ACSOmega pubs.acs.org/doi/10.1021/ac…
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