Albe van der Merwe
@intrepidsci
Musician, scientist, whacky lover of all cool things.
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We are looking for a Doctoral Candidate with a #bioinformatics background to use metagenomics to study microbial pathogens in non-clinical niches as part of #SPOILCONTROL @MSCActions DN DC5 - Pathogenic Flora spoilcontrol.hub.inrae.fr/phd-projects/d…
A new spatial transcriptomics approach eliminates the need for time-intensive imaging with specialized equipment, making the technique accessible to more researchers around the world. broad.io/ChenNews0403
Identifying 14-3-3 interactome binding sites with deep learning 1. The study introduces a deep learning framework designed to predict protein binding sites to the 14-3-3 family, central hub proteins involved in various cellular signaling processes. 2. The researchers created an…
A 100-billion-parameter unified transformer for interpreting and generating protein sequences Proteins underpin vital processes in biology, from cellular signaling to enzyme catalysis. Their amino acid sequences determine complex structural and functional properties, making it…
Long reads @nanopore @PacBio can provide insights into epigenetics. We (@fuyilei96 @timp0) summarize the latest #Bioinformatics approaches to analyze methylation & why this matters! Out now @NatureRevGenet bit.ly/4cjxUtl @BCM_HGSC @bcmgenetics @RiceCompSci @JohnsHopkins
🚀 Update! Our latest Pinal bioRxiv now includes wet lab results. More proteins with diverse text prompt on the way. Design proteins with just text. Everyone can do protein design! Demo: denovo-pinal.com paper: biorxiv.org/content/10.110… GitHub: github.com/westlake-repl/…
GeneWhisperer: Enhancing manual genome annotation with large language models biorxiv.org/content/10.110… #biorxiv_bioinfo
In a new Science study, researchers introduce GAIA, a statistical approach that seeks to learn the geographic position of every genetic ancestor of individuals included in a genome dataset. Learn more ⬇️ 📄: scim.ag/4l79zLb #SciencePerspective: scim.ag/41Owy6f
Beyond the black box with biologically informed neural networks nature.com/articles/s4157… (read free: rdcu.be/efVJ1) 🧬🖥️🧪
This right here is what I've been waiting for. nature.com/articles/s4157…
Entropy is one of those formulas that many of us learn, swallow whole, and even use regularly without really understanding. (E.g., where does that “log” come from? Are there other possible formulas?) Yet there's an intuitive & almost inevitable way to arrive at this expression.
PI trying to finish a paper despite incessant problems, meetings, and a million other distractions.
We are incredibly small and insignificant. But we are intrepidly exploring the cosmos with technology made with human hands and human brains. First #JWST deep field shows thousands of galaxies and gravitational lensing. Things with lens flares = stars that are much closer to us.
The first image from the Webb Space Telescope represents a historic moment for science and technology. For astronomy and space exploration. And for America and all humanity.
How fortunate we are to live in an age where we can see things in the sky that would have been hidden forever without technology @NASA #JWST. If I had this toy, I would spend all my time frantically pointing it at things seen before or not. #nosleep nasa.gov/image-feature/…
Changing the name of a thing to increase the number of syllables doesn't change the nature of the thing. Shell-shocked is now "post traumatic stress syndrome", blackout is now "load shedding". Politicians need to grow the f up.
SCIENCE: If you don't make mistakes, you're doing it wrong. If you don't correct those mistakes, you're doing it really wrong. If you can't accept that you're mistaken, you're not doing it at all.
This feels ridiculously relevant right now
The first image from the Webb Space Telescope represents a historic moment for science and technology. For astronomy and space exploration. And for America and all humanity.
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