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Jay Chandar

@jaychandar5

Jay Chandar reposted

Christian K. Ramsoomair, a fifth-year M.D./Ph.D. student at @umiamimedicine, has been awarded the prestigious @theNCI F30 fellowship to advance cancer research at Sylvester. 🙌 Discover how mentorship at Miller School and Sylvester is shaping the future of cancer research:…


Jay Chandar reposted

A while coming, our NIH R25-funded work on GBM LMD was published exposing the TLR-4 pathway as relevant, and more importantly for me, lays foundations for active cerebrospinal fluid (CSF) exchange studies to make clinical change. @AshishHShah4

victorlumd's tweet image. A while coming, our NIH R25-funded work on GBM LMD was published exposing the TLR-4 pathway as relevant, and more importantly for me, lays foundations for active cerebrospinal fluid (CSF) exchange studies to make clinical change. @AshishHShah4

Jay Chandar reposted

Congrats to our amazing MD PhD student @CKRamsoomair on receiving his NCI F30 grant this week to study pediatric brain tumors! Chris is an rockstar student, scientist and friend! We’re lucky to have him in the @um_svilab! He is co-mentored w/ the epigenetic guru @ReinbergDanny

AshishHShah4's tweet image. Congrats to our amazing MD PhD student @CKRamsoomair on receiving his NCI F30 grant this week to study pediatric brain tumors! Chris is an rockstar student, scientist and friend! We’re lucky to have him in the @um_svilab! He is co-mentored w/ the epigenetic guru @ReinbergDanny
AshishHShah4's tweet image. Congrats to our amazing MD PhD student @CKRamsoomair on receiving his NCI F30 grant this week to study pediatric brain tumors! Chris is an rockstar student, scientist and friend! We’re lucky to have him in the @um_svilab! He is co-mentored w/ the epigenetic guru @ReinbergDanny

Jay Chandar reposted

Great talk by @CKRamsoomair discussing the role of neurosurgeons in brain tumor clinical trials! Christian is a rising superstar in neurosurgery! @UMneurosurgery @um_svilab

AshishHShah4's tweet image. Great talk by @CKRamsoomair discussing the role of neurosurgeons in brain tumor clinical trials! Christian is a rising superstar in neurosurgery! @UMneurosurgery @um_svilab
AshishHShah4's tweet image. Great talk by @CKRamsoomair discussing the role of neurosurgeons in brain tumor clinical trials! Christian is a rising superstar in neurosurgery! @UMneurosurgery @um_svilab

Jay Chandar reposted

Thrilled that we are enrolling for STARLITE phase 1 trial for newly diag. unresectable GBM. We will combine FDA-approved antiretroviral drugs +Laser ablation+SOC. The trial leverages the anticancer effects of ART to target treatment resistant GBM stem cell niche. NCT06428045

AshishHShah4's tweet image. Thrilled that we are enrolling for STARLITE phase 1 trial for newly diag. unresectable GBM. We will combine FDA-approved antiretroviral drugs +Laser ablation+SOC.  The trial leverages the anticancer effects of ART to target treatment resistant GBM stem cell niche. 
NCT06428045
AshishHShah4's tweet image. Thrilled that we are enrolling for STARLITE phase 1 trial for newly diag. unresectable GBM. We will combine FDA-approved antiretroviral drugs +Laser ablation+SOC.  The trial leverages the anticancer effects of ART to target treatment resistant GBM stem cell niche. 
NCT06428045

Jay Chandar reposted

Congrats @CKRamsoomair! Excited for your talk at @AANSNeuro!

Excited for the opportunity to give an oral presentation on Neurosurgical Leadership in Neuro-Oncology Clinical Trials at this year’s @AANSNeuro Annual Meeting in Boston! @AshishHShah4 @umiamimedicine @UMneurosurgery

CKRamsoomair's tweet image. Excited for the opportunity to give an oral presentation on Neurosurgical Leadership in Neuro-Oncology Clinical Trials at this year’s @AANSNeuro Annual Meeting in Boston! 

@AshishHShah4 @umiamimedicine @UMneurosurgery


Jay Chandar reposted

Really excited about this awesome group!

Starkeneurosurg's tweet image. Really excited about this awesome group!

Jay Chandar reposted

Tapping ancient viral DNA in the treatment of glioblastoma! @AshishHShah4 @SeetharamDeepa @jaychandar5 & team @umiamimedicine show the zinc finger protein ZNF638 activates viral mimicry to promote immune checkpoint inhibition in preclinical models of glioblastoma:…

jclinicalinvest's tweet image. Tapping ancient viral DNA in the treatment of glioblastoma! 

@AshishHShah4 @SeetharamDeepa @jaychandar5 & team @umiamimedicine show the zinc finger protein ZNF638 activates viral mimicry to promote immune checkpoint inhibition in preclinical models of glioblastoma:…

It’s a dream come true to join this amazing program. Thank you to everyone at UM for this opportunity and for all of your support. Can’t wait for these next 7 years. @UMneurosurgery @AllanLeviMD @Ricardokomotar @AshishHShah4

So excited about our incoming 2025 class! Congratulations, Dr. Megan Sharpe, Dr. Andrew Wang, Dr. Jay Chandar and Dr. Daksh Chauhan! Welcome to @UMneurosurgery ! 🙌 #matchday #neurosurgery

AllanLeviMD's tweet image. So excited about our incoming 2025 class! Congratulations, Dr. Megan Sharpe, Dr. Andrew Wang, Dr. Jay Chandar and Dr. Daksh Chauhan! Welcome to @UMneurosurgery ! 🙌
#matchday #neurosurgery


Jay Chandar reposted

📢 STARLITE Phase 1 Study. Groundbreaking clinical trial to explore a potential new treatment for unresectable high-grade gliomas. This study aims to assess how these tumors respond to a combination of MR-guided Laser Interstitial Thermal Therapy (LITT) and antiretroviral drugs.


Jay Chandar reposted

Thrilled to share our @um_svilab work published today in @jclinicalinvest focused on harnessing viral mimicry to activate immunotherapy for #GBM. Thanks to all of my @SylvesterCancer @UMneurosurgery colleagues for their invaluable contributions! jci.org/articles/view/…

AshishHShah4's tweet image. Thrilled to share our @um_svilab work published today in @jclinicalinvest focused on harnessing viral mimicry to activate immunotherapy for #GBM. Thanks to all of my @SylvesterCancer @UMneurosurgery colleagues for their invaluable contributions! 
jci.org/articles/view/…

Jay Chandar reposted

Challenging resection of a large C7 intramedullary hemangioblastoma that had undergone previous biopsy at an outside hospital. @EvaWuMD Angio Embo - Ty @Starkeneurosurg #Neurosurgery


Jay Chandar reposted

Lot of things to be grateful for this week in the lab! 1. @SeetharamDeepa @jaychandar5 got their paper accepted on activating immunotherapy ! 2. @VaidyaGovind15 received a training grant to study GBM exosomes ! 3. @CKRamsoomair recent operative pub on virotherapy techniques!

AshishHShah4's tweet image. Lot of things to be grateful for this week in the lab!
1. @SeetharamDeepa @jaychandar5 got their paper accepted on activating immunotherapy ! 
2. @VaidyaGovind15 received a training grant to study GBM exosomes ! 
3. @CKRamsoomair recent operative pub on virotherapy  techniques!
AshishHShah4's tweet image. Lot of things to be grateful for this week in the lab!
1. @SeetharamDeepa @jaychandar5 got their paper accepted on activating immunotherapy ! 
2. @VaidyaGovind15 received a training grant to study GBM exosomes ! 
3. @CKRamsoomair recent operative pub on virotherapy  techniques!
AshishHShah4's tweet image. Lot of things to be grateful for this week in the lab!
1. @SeetharamDeepa @jaychandar5 got their paper accepted on activating immunotherapy ! 
2. @VaidyaGovind15 received a training grant to study GBM exosomes ! 
3. @CKRamsoomair recent operative pub on virotherapy  techniques!

Jay Chandar reposted

Happy holidays from @um_svilab ! Blessed to have such a wonderful motivated and fun team! 🥼Holiday 🍕 party at Casa de Shah. Delicious chocolate cake courtesy of @GarciaNevett @UMneurosurgery @SylvesterCancer @SeetharamDeepa @CKRamsoomair @jaychandar5 @VaidyaGovind15

AshishHShah4's tweet image. Happy holidays from @um_svilab ! Blessed to have such a wonderful motivated and fun team! 🥼Holiday 🍕 party at Casa de Shah. Delicious chocolate cake courtesy of @GarciaNevett @UMneurosurgery @SylvesterCancer @SeetharamDeepa @CKRamsoomair @jaychandar5 @VaidyaGovind15

Jay Chandar reposted

Excited to share our @biorxivpreprint focusing on epigenetic potentiation of immunotherapy for #GBM through viral mimicry! Congrats @jaychandar5 @CKRamsoomair @DeepaSeetharam for their hard work and all our colleagues who contributed to this manuscript! biorxiv.org/content/10.110…


Jay Chandar reposted

Targeting ZNF638 activates antiviral immune responses and potentiates immune checkpoint inhibition in glioblastoma biorxiv.org/cgi/content/sh… #biorxiv_cancer


Jay Chandar reposted

Great time @CNS_Update in HOU! We had a great time learning about cutting edge neurosurgery and presenting our brain tumor work! Also congrats to Ray Castro from @SylvesterCancer for winning top tumor poster! @JustinTaylorLab @um_svilab @UMneurosurgery @jaychandar5 @CKRamsoomair

AshishHShah4's tweet image. Great time @CNS_Update in HOU! We had a great time learning about cutting edge neurosurgery and presenting our brain tumor work! Also congrats to Ray Castro from @SylvesterCancer for winning top tumor poster! @JustinTaylorLab @um_svilab @UMneurosurgery @jaychandar5 @CKRamsoomair
AshishHShah4's tweet image. Great time @CNS_Update in HOU! We had a great time learning about cutting edge neurosurgery and presenting our brain tumor work! Also congrats to Ray Castro from @SylvesterCancer for winning top tumor poster! @JustinTaylorLab @um_svilab @UMneurosurgery @jaychandar5 @CKRamsoomair
AshishHShah4's tweet image. Great time @CNS_Update in HOU! We had a great time learning about cutting edge neurosurgery and presenting our brain tumor work! Also congrats to Ray Castro from @SylvesterCancer for winning top tumor poster! @JustinTaylorLab @um_svilab @UMneurosurgery @jaychandar5 @CKRamsoomair
AshishHShah4's tweet image. Great time @CNS_Update in HOU! We had a great time learning about cutting edge neurosurgery and presenting our brain tumor work! Also congrats to Ray Castro from @SylvesterCancer for winning top tumor poster! @JustinTaylorLab @um_svilab @UMneurosurgery @jaychandar5 @CKRamsoomair

Jay Chandar reposted

Congrats @jaychandar5 for winning best medical student research presentation at the @FloridaNeuro society meeting this weekend!! @um_svilab @UMneurosurgery @SeetharamDeepa

AshishHShah4's tweet image. Congrats @jaychandar5 for winning best medical student research presentation at the @FloridaNeuro society meeting this weekend!! @um_svilab @UMneurosurgery @SeetharamDeepa

Jay Chandar reposted

Our preclinical study on antiretroviral drug repositioning for GBM was published! Our main findings were that certain anti-retroviral drugs have preclinical efficacy and neuropenetrance in GBM. Were translating some of these findings to a clinical trial here @um_svilab

AshishHShah4's tweet image. Our preclinical study on antiretroviral drug repositioning for GBM was published! Our main findings were that certain anti-retroviral drugs have preclinical efficacy and neuropenetrance in GBM. Were translating some of these findings to a clinical trial here @um_svilab
AshishHShah4's tweet image. Our preclinical study on antiretroviral drug repositioning for GBM was published! Our main findings were that certain anti-retroviral drugs have preclinical efficacy and neuropenetrance in GBM. Were translating some of these findings to a clinical trial here @um_svilab

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