Saurav Choudhary
@saurav317
PhD student at @universityofga | MTech (@IIITDelhi)
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A spectacular win by the Indian team in the ICC Women’s Cricket World Cup 2025 Finals. Their performance in the final was marked by great skill and confidence. The team showed exceptional teamwork and tenacity throughout the tournament. Congratulations to our players. This…
So many people keep asking me about Continue. What is it? What are you up to? Here you go... Continue started as a research effort two years ago, with the belief that if the human body is a system, it should also have its leverage points. The simple levers that, when adjusted,…
Have to stay at home this year for a newborn baby. But the Ye lab is well-represented #ASHG25. Check out the posters from our 7 grad students!
Congrats to @xx_huifang and @YitangS for their tremendous efforts on this project to characterize the shared genetic basis between circulating fatty acids and brain disorders!
Latest publication in @jlipidres “Widespread but moderate genetic overlap between circulating polyunsaturated fatty acids and brain disorders” by @xx_huifang et al. jlr.org/article/S0022-… @YitangS @yekaixiong @CharlestonCWKC @ASBMB
It is a major PhD project of @YitangS. I am very excited to see this work out. I learned so much about the genetics of circulating fatty acids. This is a solid foundation for more research to come regarding gene-diet interactions for omega-3 and omega-6 fatty acids.
The latest @HGGAdvances article from @yekaixiong & colleagues reports the results of a genome-wide association study that identifies additional genetic loci for 19 circulating fatty acid traits in UK Biobank participants of European ancestry: cell.com/hgg-advances/f… #ASHG
Zero-shot evaluation reveals limitations of single-cell foundation models genomebiology.biomedcentral.com/articles/10.11…
We will be at #ASHG24 next week. Multiple students from the lab will be presenting their research. Look forward to it!
Spatial omics have lit up life science and this new review @CellCellPress is the best I've seen cell.com/cell/fulltext/… open-access
A benchmark of single-cell ATAC-seq analysis packages. genomebiology.biomedcentral.com/articles/10.11…
Very excited to share our primer on LLM for biology @naturemethods! We discuss how to use: ⚡️human & protein LMs (eg #ESM) ⚡️#singlecell & #multimodel LMs ⚡️when to fine-tune, transfer learn etc. Paper nature.com/articles/s4159… Colab tutorial colab.research.google.com/drive/1zIIRGeq… Written for a…
Excited to share our study on fish oil supplements modifying genetic effects on lipids, now published in @AJCNutrition: doi.org/10.1016/j.ajcn…. Thanks to all co-authors!
This is a news report on our recent study published on @AJCNutrition doi.org/10.1016/j.ajcn… led by @YitangS
I'm sharing a public version of my talk slides @UCLA_CGSI two weeks ago - an update from my #LLMs #compbio Primer talk last year - w/ a focus on genomics FMs (DNA, scRNA). As we're exploring related topics, we remain very interested but also skeptical. 1/3 cs.cmu.edu/~jianma/talks/…
Pangene now published in Bioinformatics: doi.org/10.1093/bioinf…. In addition to showcasing applications (see the 17q21.31 inversion below), we also reviewed the theoretical formulation of bidirected graphs and discussed the definition and the finding of "bubbles" in such graphs.
Preprint on Exploring gene content with pangenome gene graphs: arxiv.org/abs/2402.16185. It describes pangene for building gene graphs and for calling gene-level variations which can be found at pangene.bioinweb.org. Pleasant collaboration with @maxgmarin and @MahaFarhat.
Our study of the gene-vegetarianism interaction effects on 30 blood biomarkers is formally published on #PLOSGenetics dx.plos.org/10.1371/journa…
Takeaways: 1) Elections are fair; 2) EVMs are not rigged; 3) Threatening civil war is stupid - it’s an election not a war; 4) exit polls are great fun but the real thing is the actual result; 5) we are back to coalitions and we can forget about any serious reforms - economic or…
Genome assembly in the telomere-to-telomere era go.nature.com/4aLqIED #Review by Heng Li @lh3lh3 & Richard Durbin @richard_durbin @DanaFarber @HarvardDBMI @Cambridge_Uni
I'm delighted to release the first half of my new open-access online textbook in human population genetics: web.stanford.edu/group/pritchar…
Does single-cell data increase probability of success in drug discovery and clinical success? 🧐 Drug targets backed by single-cell data triple the chances of a target reaching phase III, when combined with genetic data 🎯 Read the pre-print of this brilliant study by @sanofi…
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