#planarcellpolarity search results
@r_piscitel presents her PhD project at the last friday seminar @mpicbg - demonstrating her unique ability to tackle brave questions connecting #planarcellpolarity and #tissuemechanics.
20 years ago! When @NIDCD working on #Wnt and #PlanarCellPolarity Cover of @Dev_journal. @UofT_LMP @uoftmedicine @Sunnybrook #Cochlea #InnerEar
#DBfeature #PlanarCellPolarity #TouretteSyndrome Planar cell polarity and the pathogenesis of Tourette Disorder: New hypotheses and perspectives by Junbing Wu, Lauren Poppi, Max Tischfield @LaurenPoppi @tischfield CELSR3, a protocadherin GPCR sciencedirect.com/science/articl…
#DBfeature Inter-growth cone communication mediated by #PlanarCellPolarity pathway in #AxonGuidance by Yimin Zou @yiminzounew "LRRK primarily regulates a previous unappreciated aspect of Frizzled3 function, which is axon-axon organization" sciencedirect.com/science/articl…
Vangl2, #PlanarCellPolarity protein, in Kidney Morphogenesis Vangl2 lp/lp🐭 👉Kidney Hypoplasia e13.5~18.5 👉⏬Ureteric Budding/#BranchingMorphogenesis e13.5 👉Absent renal pelvis e18.5 👉Lack bush border/epithelial microvilli in proximal tubule e18.5 👉Smaller Glomerular tufts;…
Read #SDBSciCommIntern @RefriedEctoderm new interview with @maureencetera @UMNews. “I found this fascinating image of this mouse that just had whorls in [the back] half of its body, which just did not make any sense to me,” said Cetera. #planarcellpolarity bit.ly/3SwLa4r
![SocDevBio's tweet image. Read #SDBSciCommIntern @RefriedEctoderm new interview with @maureencetera @UMNews. “I found this fascinating image of this mouse that just had whorls in [the back] half of its body, which just did not make any sense to me,” said Cetera. #planarcellpolarity bit.ly/3SwLa4r](https://pbs.twimg.com/media/GFmr2G_W8AA0Qk7.jpg)
![SocDevBio's tweet image. Read #SDBSciCommIntern @RefriedEctoderm new interview with @maureencetera @UMNews. “I found this fascinating image of this mouse that just had whorls in [the back] half of its body, which just did not make any sense to me,” said Cetera. #planarcellpolarity bit.ly/3SwLa4r](https://pbs.twimg.com/media/GFmr3kdWEAAuXbO.png)
Nestin+ Neural KO of Fat1, atypical cadherin in #PlanarCellPolarity-> Retinal vascular anomalies -⏫Vascular length+branch density -Ectopic veins even in OPL😎 -Capillary #Pericyte muscularization Dr. Françoise Helmbacher @F_Helmbacher @Dev_journal 2022 journals.biologists.com/dev/article/14…
Check out this recent publication from one of our researchers based in Toronto. Congratulations, Masha!! pnas.org/content/early/… #hydra #PlanarCellPolarity #FatLike #Dachsous
Shear-VEGFA interplay on #EndothelialCell A complex role of VEGFR2 EC responses (Alignment+#PlanarCellPolarity+Junction+FA) to low vs high (3 vs 20 dyn/cm2) laminar shear are differentially modified by VEGF-A Dr Holger Gerhardt lab @FrontPhysiol 2021 frontiersin.org/articles/10.33…
Proud to announce our epos on the multi-scale coordination of #cellpolarity and #planarcellpolarity at biorxiv.org/content/early/… Featuring the formidable first authors @Soor88 and @meo0205, @TheGeneMyers and Azimzadeh labs and #planaria, of course. And 6 years of hard work :)
A surprising role of Vangl1/2 in Tbx4+ Mesenchyme (not Shh+ Epithelia) during🐭Lung #BranchingMorphologenesis An amazing role of Vang1/2 in Airway #SmoothMuscleCell Alignment/Wrapping CELSR1 is only detectable in developing🐭🫁epithelia/mesothelia, so core #PlanarCellPolarity…
#DBfeature #Ear👂 #PlanarCellPolarity Planar cell polarity signaling guides cochlear innervation by Mike Deans @DeansNeuroNow Growth cone interprets "planar polarized patterning of the environment through which it travels via transient PCP signaling" sciencedirect.com/science/articl…
Vangl2 #PlanarCellPolarity in Coronary vascularization🫀 Vangl2 lp/lp🐭 1⃣Ectopic, dilated, tortuous coronary vessels e13.5 ~18.5 2⃣Unaltered epicardial differentiation (WT1, RALDH2), but +diminished Fibronectin deposit e13.5 +flattened epicardium +⏬epicardial EMT/inward…
Wnt #PlanarCellPolarity #Angiogenesis The ubiquitin ligase PDZRN3 is required for vascular morphogenesis through Wnt/planar cell polarity signalling Dr. Cécile Duplàa lab @NatureComms 2014 nature.com/articles/ncomm…
Cardiomyocyte (Nkx2.5-Cre) Rac1 KO causes🐭congenital heart defects with⏬Scribb (#PlanarCellPolarity protein) abundance & compromised cardiomyocte organization/proliferation Dr. Qingping Feng lab @JCDD_MDPI 2021 @QFeng3 @SchulichMedDent @westernuPandP mdpi.com/2308-3425/8/3/…
More on mechanosensing & pattern formation; hPSC-derived neural tube like structures bit.ly/3cGWjKG @AdrianRanga1lab. We are slowly learning @ this key signalling source in Developmental Biology and, probably also, disease #stiffness #contractility #PlanarCellPolarity
Excited to share our latest pre-print! Great work from PDF Michael Housset! If you are interested in #vision #planarcellpolarity #retina #cellbiology you might be interested to read this short thread. biorxiv.org/content/10.110…
Researchers discover a novel mechanism regulating #planarcellpolarity @hkust @jbiolchem phys.org/news/2020-07-m…
phys.org
Researchers discover a novel mechanism regulating planar cell polarity
Planar cell polarity (PCP), a process in which the epithelial tissues are polarized within the plane of the epithelium, plays an important role in development and organ function. Defects in PCP are...
A surprising role of Vangl1/2 in Tbx4+ Mesenchyme (not Shh+ Epithelia) during🐭Lung #BranchingMorphologenesis An amazing role of Vang1/2 in Airway #SmoothMuscleCell Alignment/Wrapping CELSR1 is only detectable in developing🐭🫁epithelia/mesothelia, so core #PlanarCellPolarity…
Vangl2, #PlanarCellPolarity protein, in Kidney Morphogenesis Vangl2 lp/lp🐭 👉Kidney Hypoplasia e13.5~18.5 👉⏬Ureteric Budding/#BranchingMorphogenesis e13.5 👉Absent renal pelvis e18.5 👉Lack bush border/epithelial microvilli in proximal tubule e18.5 👉Smaller Glomerular tufts;…
Vangl2 #PlanarCellPolarity in Coronary vascularization🫀 Vangl2 lp/lp🐭 1⃣Ectopic, dilated, tortuous coronary vessels e13.5 ~18.5 2⃣Unaltered epicardial differentiation (WT1, RALDH2), but +diminished Fibronectin deposit e13.5 +flattened epicardium +⏬epicardial EMT/inward…
Wednesday at 1 p.m. Eastern ➡️➡️ @yiminzounew of @ucsdbiosciences will highlight how #planarcellpolarity proteins assemble #glutamatergic synapses and regulate #synapticplasticity. Find the #IPISeminar link on our events calendar! calendar.google.com/calendar/u/0/e…
Read #SDBSciCommIntern @RefriedEctoderm new interview with @maureencetera @UMNews. “I found this fascinating image of this mouse that just had whorls in [the back] half of its body, which just did not make any sense to me,” said Cetera. #planarcellpolarity bit.ly/3SwLa4r
New paper from Sabine Cordes & co @UofT @SinaiHealth identifies an interaction between OTULIN and SCRIB that uncovers roles for linear ubiquitination in #PlanarCellPolarity & showed a role for OTULIN in #NeuralTube development journals.biologists.com/dmm/article/16… #OpenAccess
20 years ago! When @NIDCD working on #Wnt and #PlanarCellPolarity Cover of @Dev_journal. @UofT_LMP @uoftmedicine @Sunnybrook #Cochlea #InnerEar
#DBfeature Inter-growth cone communication mediated by #PlanarCellPolarity pathway in #AxonGuidance by Yimin Zou @yiminzounew "LRRK primarily regulates a previous unappreciated aspect of Frizzled3 function, which is axon-axon organization" sciencedirect.com/science/articl…
#DBfeature #PlanarCellPolarity #TouretteSyndrome Planar cell polarity and the pathogenesis of Tourette Disorder: New hypotheses and perspectives by Junbing Wu, Lauren Poppi, Max Tischfield @LaurenPoppi @tischfield CELSR3, a protocadherin GPCR sciencedirect.com/science/articl…
To all #Planarcellpolarity #PCP #AIS aficionados, please have a look to our latest work. Big congrats to @adorrego_r and special thanks to all @PlanarPolarityT members and nice collaborators with twitter accounts @arne_feld and @FreAmeLie ! This is cool!
Short version: our results define Prickle2 (Pk2) as a neuronal polarity determinant and a new component of the AIS, participating in its early assembly and stabilization via direct binding to AnkG and #microtubules (MT) bundling science.org/doi/10.1126/sc…
Nestin+ Neural KO of Fat1, atypical cadherin in #PlanarCellPolarity-> Retinal vascular anomalies -⏫Vascular length+branch density -Ectopic veins even in OPL😎 -Capillary #Pericyte muscularization Dr. Françoise Helmbacher @F_Helmbacher @Dev_journal 2022 journals.biologists.com/dev/article/14…
When you get a PhD student, get one like @michaela_raab from @mrc_hgu. She stormed to victory today with an excellent @3MT_official finals presentation @EdinburghUni and watch this space for her pre-print coming soon - turns out #planarcellpolarity does more than we thought…
#DBfeature #Ear👂 #PlanarCellPolarity Planar cell polarity signaling guides cochlear innervation by Mike Deans @DeansNeuroNow Growth cone interprets "planar polarized patterning of the environment through which it travels via transient PCP signaling" sciencedirect.com/science/articl…
Wnt #PlanarCellPolarity #Angiogenesis The ubiquitin ligase PDZRN3 is required for vascular morphogenesis through Wnt/planar cell polarity signalling Dr. Cécile Duplàa lab @NatureComms 2014 nature.com/articles/ncomm…
Thank you program committe @AROMWM for giving me an opportunity to share my work @WaltersLabUMMC ! If you have attended my talk and have any questions, suggestions, please feel free to reach out #Planarcellpolarity #inner ear
Thrilled to share with you the review we wrote with Thomas @LecuitLab for #CurrentOpinionInGeneticsDevelopment where we discuss the potential common principles of #PlanarCellPolarity😃 Looking forward for your feedback! authors.elsevier.com/c/1eBF~,LqAZQA… @IBDMmarseille @cdf1530 @centuri_ls
Cardiomyocyte (Nkx2.5-Cre) Rac1 KO causes🐭congenital heart defects with⏬Scribb (#PlanarCellPolarity protein) abundance & compromised cardiomyocte organization/proliferation Dr. Qingping Feng lab @JCDD_MDPI 2021 @QFeng3 @SchulichMedDent @westernuPandP mdpi.com/2308-3425/8/3/…
A thread on our recent paper from @LecuitLab in @Dev_Cell on how Toll receptors and the GPCR Cirl cooperate to form polarized contractile interfaces! #Morphogenesis #PlanarCellPolarity #OpenAccess ➡️cell.com/developmental-… @IBDMmarseille @cdf1530 @centuri_ls @MaP_Proteomique 1/👇
cell.com
Formation of polarized contractile interfaces by self-organized Toll-8/Cirl GPCR asymmetry
Lavalou, Mao et al. report that Toll-8 controls myosin-II planar polarity in Drosophila embryos and wing discs via a physical interaction with the GPCR Cirl/latrophilin. They show that Toll-8...
Shear-VEGFA interplay on #EndothelialCell A complex role of VEGFR2 EC responses (Alignment+#PlanarCellPolarity+Junction+FA) to low vs high (3 vs 20 dyn/cm2) laminar shear are differentially modified by VEGF-A Dr Holger Gerhardt lab @FrontPhysiol 2021 frontiersin.org/articles/10.33…
#DBfeature #PlanarCellPolarity #TouretteSyndrome Planar cell polarity and the pathogenesis of Tourette Disorder: New hypotheses and perspectives by Junbing Wu, Lauren Poppi, Max Tischfield @LaurenPoppi @tischfield CELSR3, a protocadherin GPCR sciencedirect.com/science/articl…
@r_piscitel presents her PhD project at the last friday seminar @mpicbg - demonstrating her unique ability to tackle brave questions connecting #planarcellpolarity and #tissuemechanics.
20 years ago! When @NIDCD working on #Wnt and #PlanarCellPolarity Cover of @Dev_journal. @UofT_LMP @uoftmedicine @Sunnybrook #Cochlea #InnerEar
#DBfeature Inter-growth cone communication mediated by #PlanarCellPolarity pathway in #AxonGuidance by Yimin Zou @yiminzounew "LRRK primarily regulates a previous unappreciated aspect of Frizzled3 function, which is axon-axon organization" sciencedirect.com/science/articl…
Read #SDBSciCommIntern @RefriedEctoderm new interview with @maureencetera @UMNews. “I found this fascinating image of this mouse that just had whorls in [the back] half of its body, which just did not make any sense to me,” said Cetera. #planarcellpolarity bit.ly/3SwLa4r
Nestin+ Neural KO of Fat1, atypical cadherin in #PlanarCellPolarity-> Retinal vascular anomalies -⏫Vascular length+branch density -Ectopic veins even in OPL😎 -Capillary #Pericyte muscularization Dr. Françoise Helmbacher @F_Helmbacher @Dev_journal 2022 journals.biologists.com/dev/article/14…
#DBfeature #Ear👂 #PlanarCellPolarity Planar cell polarity signaling guides cochlear innervation by Mike Deans @DeansNeuroNow Growth cone interprets "planar polarized patterning of the environment through which it travels via transient PCP signaling" sciencedirect.com/science/articl…
Shear-VEGFA interplay on #EndothelialCell A complex role of VEGFR2 EC responses (Alignment+#PlanarCellPolarity+Junction+FA) to low vs high (3 vs 20 dyn/cm2) laminar shear are differentially modified by VEGF-A Dr Holger Gerhardt lab @FrontPhysiol 2021 frontiersin.org/articles/10.33…
Cardiomyocyte (Nkx2.5-Cre) Rac1 KO causes🐭congenital heart defects with⏬Scribb (#PlanarCellPolarity protein) abundance & compromised cardiomyocte organization/proliferation Dr. Qingping Feng lab @JCDD_MDPI 2021 @QFeng3 @SchulichMedDent @westernuPandP mdpi.com/2308-3425/8/3/…
Vangl2, #PlanarCellPolarity protein, in Kidney Morphogenesis Vangl2 lp/lp🐭 👉Kidney Hypoplasia e13.5~18.5 👉⏬Ureteric Budding/#BranchingMorphogenesis e13.5 👉Absent renal pelvis e18.5 👉Lack bush border/epithelial microvilli in proximal tubule e18.5 👉Smaller Glomerular tufts;…
Check out this recent publication from one of our researchers based in Toronto. Congratulations, Masha!! pnas.org/content/early/… #hydra #PlanarCellPolarity #FatLike #Dachsous
Proud to announce our epos on the multi-scale coordination of #cellpolarity and #planarcellpolarity at biorxiv.org/content/early/… Featuring the formidable first authors @Soor88 and @meo0205, @TheGeneMyers and Azimzadeh labs and #planaria, of course. And 6 years of hard work :)
A surprising role of Vangl1/2 in Tbx4+ Mesenchyme (not Shh+ Epithelia) during🐭Lung #BranchingMorphologenesis An amazing role of Vang1/2 in Airway #SmoothMuscleCell Alignment/Wrapping CELSR1 is only detectable in developing🐭🫁epithelia/mesothelia, so core #PlanarCellPolarity…
Vangl2 #PlanarCellPolarity in Coronary vascularization🫀 Vangl2 lp/lp🐭 1⃣Ectopic, dilated, tortuous coronary vessels e13.5 ~18.5 2⃣Unaltered epicardial differentiation (WT1, RALDH2), but +diminished Fibronectin deposit e13.5 +flattened epicardium +⏬epicardial EMT/inward…
Wnt #PlanarCellPolarity #Angiogenesis The ubiquitin ligase PDZRN3 is required for vascular morphogenesis through Wnt/planar cell polarity signalling Dr. Cécile Duplàa lab @NatureComms 2014 nature.com/articles/ncomm…
Special Issue: Cell Polarity and Tissue Morphogenesis: Discoveries and New Insights welcomes your research and review articles. mdpi.com/journal/life/s… #MDPI #Life #PlanarCellPolarity #Biology
New paper from Sabine Cordes & co @UofT @SinaiHealth identifies an interaction between OTULIN and SCRIB that uncovers roles for linear ubiquitination in #PlanarCellPolarity & showed a role for OTULIN in #NeuralTube development journals.biologists.com/dmm/article/16… #OpenAccess
Wednesday at 1 p.m. Eastern ➡️➡️ @yiminzounew of @ucsdbiosciences will highlight how #planarcellpolarity proteins assemble #glutamatergic synapses and regulate #synapticplasticity. Find the #IPISeminar link on our events calendar! calendar.google.com/calendar/u/0/e…
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