#interneurons search results
A subpopulation of dorsolateral septum #somatostatin-expressing #interneurons (SST-INs) serve as hippocampal relays that govern mobility to calibrate adaptive fear responses go.nature.com/2TxjqwG
Somatostatin-expressing (SOM+) #interneurons in the mouse medial prefrontal cortex (#mPFC) mediate discrimination of positive and negative affective states in others go.nature.com/2r2leoE
The “stop and go” movement of individual migrating #cortical #interneurons is critical for ensuring a proper rate of cortical invasion for the entire population. Free article: cell.com/cell/abstract/…
A whole-brain atlas of direct long range inputs to GABAergic #interneurons in the medial #prefrontal cortex (mPFC) of male mice go.nature.com/2YGl4Pl
Activated #microglia disrupt mitochondrial function in #iPSC-derived developing cortical #interneurons that persist in interneurons from individuals with #schizophrenia go.nature.com/2HrbTir
nature.com
Activated microglia cause metabolic disruptions in developmental cortical interneurons that persist...
Nature Neuroscience - When co-cultured with activated microglia, iPSC-derived interneurons from individuals with schizophrenia and from healthy controls show defects in metabolic pathways, but only...
Key memory receptors are located on #interneurons, finds study @PNASNexus doi.org/gr4sf9 medicalxpress.com/news/2023-04-k…
Closed-loop recruitment of #striatal #interneurons prevents compulsive-like grooming behaviors in in male Sapap3 knockout mice @LizbethMG19 @c_schreiweis @eburguiere @NERBteam nature.com/articles/s4159…
nature.com
Closed-loop recruitment of striatal interneurons prevents compulsive-like grooming behaviors
Nature Neuroscience - This paper shows that compulsive-like grooming in Sapap3-knockout mice can be reduced by closed-loop optogenetic stimulation of striatal interneurons based on grooming onset...
Now in @NeuroCellPress Development & Functional Diversification of #Cortical #Interneurons by Lynette Lim, Da Mi, Alfredo Llorca & Oscar Marín @KingsCollegeLonhttp://bit.ly/2z4l2Wq
“Inhibitory Interneurons Regulate Temporal Precision and Correlations in Cortical Circuits” by Jessica Cardin @jess_cardin TiNS/TiCS Special Issue #TrendsTimeBrain #interneurons bit.ly/2ARC77F
Rather than constraining mnemonic processing, potentiation of somatostatin-expressing (SOM+) #interneurons in medial prefrontal cortex (#mPFC) represents an important causal mechanism for conditioned fear in male mice go.nature.com/2YUFKUC
A new study by Shayna Singh (@DrexelMedicine) et al. examines properties of rhythmogenic currents in spinal Shox2 #interneurons across #postnatal development 🧠 🔬 📜 Read the #Research here: buff.ly/8vBCRVT
Aberrant hippocampal mossy fibers in temporal lobe epilepsy target excitatory and inhibitory neurons onlinelibrary.wiley.com/doi/abs/10.111… FULL-LENGTH ORIGINAL RESEARCH #openaccess #epilepsy @IlaeWeb @WileyNeuro #interneurons #temporallobe
#ArticlesinPress -"A Model for Self-Organization of Sensorimotor Function: Spinal Interneuronal Integration" Jonas M.D. Enander, Gerald E. Loeb, and Henrik Jorntell #Interneurons #Nonspiking #Neuroscience @lunduniversity @USC @jonasenander ow.ly/h4lK50ITJlA
New in @TrendsNeuro Inhibitory #Interneurons Regulate Temporal Precision & Correlations in Cortical Circuits by Cardin @Yale bit.ly/2OnGoYD
“Inhibitory Interneurons Regulate Temporal Precision and Correlations in Cortical Circuits” by Jessica Cardin @jess_cardin TiNS/TiCS Special Issue #TrendsTimeBrain #interneurons bit.ly/2QZZsKj
Researchers develop new method for specializing and purifying human #stemcells into #interneurons @kingscollegelon @SciReports doi.org/grq9vj medicalxpress.com/news/2023-02-m…
Do not miss this great opportunity to perform your post-doc in Israel! Our lab has an open job for a candidate with background in optics and imaging to study the role of inhibitory #interneurons in #NeurovascularCoupling. Don't be shy and DM me for more details.
Mark your calendars: applications for the Azrieli International Postdoctoral Fellowship 2023-24 cohort open on Sept. 1, 2022. These generous postdoc positions at top Israeli academic institutions are available to candidates worldwide. More info: ow.ly/Ihe350J1Cl8
In this recent study, Felix Preuss (@Go_Neuroanatomy @yourUMG) et al. observed that inhibitory circuit motifs of cortical #somatosensory layer 5 SST #interneurons are uniform within layers but specific across layers 💡 🔬 📜 Read the #Research here: buff.ly/7NcIS62
Interneuron hypothesis of amyotrophic lateral sclerosis | Brain | Oxford Academic| ‘They’re digging in the wrong place!’ | The #ALS field has overly focused on motor #neurons for the past century: clear need to consider other areas #interneurons @magxite academic.oup.com/brain/article/…
By combining TMS with advanced EEG, van den Bos et al. probe the functional structure of the abnormal neural networks thought to drive ALS, and conclude that there is strong evidence for cortical hyperexcitability in the underlying disease process. tinyurl.com/r6akxbzx
This new work takes the next step: from what (smart dendrites) to why (to control oscillations). A huge thank you to my mentors Dietmar Schmitz & Matthew Larkum. Hope this work sparks new ideas & experiments! #Dendrites #Hippocampus #Interneurons #AcademicChatter
#newpaper ☀️☀️Welcome to read the paper by Raúl Alelú-Paz et al. | A Refined Approach to #Isolate #Interneurons for High-Validity Epigenetic Studies in #Human #BrainTissue 👉mdpi.com/2409-9279/8/3/… #epigenetics #neuroscience #DNA #molecularbiology #cellularbiology
A new study by Shayna Singh (@DrexelMedicine) et al. examines properties of rhythmogenic currents in spinal Shox2 #interneurons across #postnatal development 🧠 🔬 📜 Read the #Research here: buff.ly/8vBCRVT
Interneuron hypothesis of amyotrophic lateral sclerosis | Brain | Oxford Academic | Fundamentally, #ALS patients consistently exhibit cortical #hyperexcitability due to impaired functioning of inhibitory cortical #interneurons | @magxite #MND #brains #CST academic.oup.com/brain/article/…
ALS is a syndrome. Clarification of #network system genomes will promote #precision approach to support key structure that underlies neurological manifestations of #ALS, the #corticomotoneuronal system |@NerveCentralSYD @magxite @Sicong_T @neuraustralia pubmed.ncbi.nlm.nih.gov/39511939/
2/10 The cortex contains two main classes of neurons: excitatory “go” pyramidal cells and inhibitory “no-go” #interneurons
Clear evidence, based in living patients, that interneurons are critical players in ALS pathogenesis @magxite | Recognizing #interneurons as vital contributors in #ALS carries significant implications for developing therapies | #GABAergic medications #excitability #MND #EEG #TMS
Interneuron hypothesis of #ALS @Brain1878 | Pivotal article, reminiscent of a scene in Raiders of the Lost Ark: ‘They’re digging in the wrong place!’ | Need to consider areas, not solely the motor neurons, particularly the interneurons @magxite academic.oup.com/brain/article/…
🧠⚡️Nav1.6 gain of function -> spreading depolarization & seizures in mice. Anyone who knows if these channels are expressed in both neurons and #interneurons?
Aiba et al. identify bilateral cortical spreading depolarization in a mouse model of epilepsy linked to a sodium channel mutation. Targeting persistently open ion channels pharmacologically could help mitigate this newly discovered disease mechanism. tinyurl.com/ey2ca956
🚀 Interneurons: tiny but mighty! 🧠 In mammals, interneurons are highly diverse 🍼 Their specific identity is set early in the embryo 🔗 This diversity drives function, shaping neural circuits #Neuroscience #BrainDiversity #Interneurons
Today! Seminar with Prof @GordFishell from @harvardmed: Making up your Mind: The Nature Vs Nurture by which Cortical Interneurons are Specified ⏲️11:30-12:30 PM Learn more: bese.kaust.edu.sa/events/detail/… @BESEStudents #Neuroscience #Interneurons #Neurogenetics
Congratulations to @marco_bocchio from @durhampsych for his new paper on #interneurons in @PLOSBiology #DUresearch
Our work showing how inhibitory #interneurons of the #hippocampus regulate the #synchrony of pyramidal cell #ensembles is now published in @PLOSbiology journals.plos.org/plosbiology/ar… Summary below👇
Our work showing how inhibitory #interneurons of the #hippocampus regulate the #synchrony of pyramidal cell #ensembles is now published in @PLOSbiology journals.plos.org/plosbiology/ar… Summary below👇
Eventually we'll use iPSC(stem cell)-derived inhibitory #interneurons in surgery for #epilepsy, but still have to overcome challenges like immunogenicity. Nice review by @Beaudreault, Richard Wang, @ArielSacknovitz, Dr. Sangmi Chung, and our team. mdpi.com/2076-3425/14/1…
How do single #interneurons affect synchrony in vivo? @marco_bocchio &co show that CA1 #hippocampus interneurons form a functionally connected network that promotes synchrony between #PyramidalCells at the single neuron level #PLOSBiology plos.io/4f4tdDI
How do single #interneurons affect synchrony in vivo? @marco_bocchio &co show that CA1 #hippocampus interneurons form a functionally connected network that promotes synchrony between #PyramidalCells at the single neuron level #PLOSBiology plos.io/4f4tdDI
How do single #interneurons affect synchrony in vivo? @marco_bocchio &co show that CA1 #hippocampus interneurons form a functionally connected network that promotes synchrony between #PyramidalCells at the single neuron level #PLOSBiology plos.io/4f4tdDI
🌟 Kicking off the fall semester with our first #StemCellTalk, featuring Assoc. Prof. Daniella Ottosson! She shared exciting research on reprogramming #interneurons for cell repair & disease modeling, with insights into psychiatric diseases. Learn more ⤵️ stemcellcenter.lu.se/research-group…
⚛️ #interneurons 🆔 #interphase 💟 #intermolecular ☮️ intercellular activity, the intentionality of what fills the space between ☯️ #microtomacro ✡️ corresponds to directionality having a sense of knowing what you do it for
Aging and psychiatric disorders share disrupted synaptic transmission and accelerated transcriptomic #aging, especially in LAMP5+LHX6+ #interneurons. By @n_gerstner, @MaikKoedel, @natan_yusupov, @natalie_matosin, @CChatzinakos, @JanineArloth, et al. doi.org/10.1038/s41593…
Inhibitory circuits in the #OlfactoryBulb shape info on its way from peripheral receptors to the cortex downstream. @NNUrban &co show that fast-spiking #interneurons perisomatically inhibit projection #neurons in the OB via synaptic detonation #PLOSBiology plos.io/4cFxDiV
A subpopulation of dorsolateral septum #somatostatin-expressing #interneurons (SST-INs) serve as hippocampal relays that govern mobility to calibrate adaptive fear responses go.nature.com/2TxjqwG
Somatostatin-expressing (SOM+) #interneurons in the mouse medial prefrontal cortex (#mPFC) mediate discrimination of positive and negative affective states in others go.nature.com/2r2leoE
A whole-brain atlas of direct long range inputs to GABAergic #interneurons in the medial #prefrontal cortex (mPFC) of male mice go.nature.com/2YGl4Pl
Rather than constraining mnemonic processing, potentiation of somatostatin-expressing (SOM+) #interneurons in medial prefrontal cortex (#mPFC) represents an important causal mechanism for conditioned fear in male mice go.nature.com/2YUFKUC
Now in @NeuroCellPress Development & Functional Diversification of #Cortical #Interneurons by Lynette Lim, Da Mi, Alfredo Llorca & Oscar Marín @KingsCollegeLonhttp://bit.ly/2z4l2Wq
2 distinct sub-classes of inhibitory #interneurons modulate different forms of spatial representation @MayBrittMoser bit.ly/2yY92r6
New in @TrendsNeuro Inhibitory #Interneurons Regulate Temporal Precision & Correlations in Cortical Circuits by Cardin @Yale bit.ly/2OnGoYD
The “stop and go” movement of individual migrating #cortical #interneurons is critical for ensuring a proper rate of cortical invasion for the entire population. Free article: cell.com/cell/abstract/…
Aberrant hippocampal mossy fibers in temporal lobe epilepsy target excitatory and inhibitory neurons onlinelibrary.wiley.com/doi/abs/10.111… FULL-LENGTH ORIGINAL RESEARCH #openaccess #epilepsy @IlaeWeb @WileyNeuro #interneurons #temporallobe
MARTES 15/10 15:00 Salón de Actos - #Seminario Área #Neurociencias. “Functional role of cortical #interneurons revealed by in-vivo two-photon #imaging”. Dr. Pablo García-Junco Clemente, Investigador Ramón y Cajal IBiS, Grupo “Fisiología Molecular de la Sinapsis”.
“Shedding Light on Chandelier Cell Development, Connectivity, and Contribution to Neural Disorders” by Nicholas Gallo, Anirban Paul & Linda Van Aelst @TrendsNeuro Review, now online cell.com/trends/neurosc… #interneurons #schizophrenia #ASD #epilepsy
📖Optogenetic activation of septal inhibitory cells abates focal seizures by Maxime Lévesque et al. 🖱ow.ly/mrp550OBgB8 #hippocampus #interneurons #MedialSeptum #MesialTemporalLobeEpilepsy #optogenetics
Interested in cortical #interneurons? Join us on Sunday July 8 at 9:45 am in Hall A7 for a symposium on the ‘Developmental logic underlying the functional diversity of cortical interneurons’ @FENSorg #FENS2018 with @GordFishell Elly Nedivi @Rico_lab and @MarinLab ⬇︎ thread
The power of the autapse. Fast autaptic self-inhibition is the major output of parvalbumin-positive basket cells in the #neocortex and serves to modulate phase-locking of these #interneurons during gamma-oscillations #PLOSBiology plos.io/2m1u1Eo
A new study shows that it is #astrocytes (non-neuronal brain cells), not neurons, that determine when #interneurons mature during development of the mouse visual system. @NathalieRouach ow.ly/gQUm50FpbM2
Thank you Dr Hunt @hunt_lab for the great talk about interneurons and the control of memory precision at @EinsteinMed #interneurons #neuroscience
#Interneurons interlaced with excitatory #neurons from frontal #cortex. Color in this and the many following images indicates what is firing at that moment in time. #art #brain #neuro #sciart
#ArticlesinPress -"A Model for Self-Organization of Sensorimotor Function: Spinal Interneuronal Integration" Jonas M.D. Enander, Gerald E. Loeb, and Henrik Jorntell #Interneurons #Nonspiking #Neuroscience @lunduniversity @USC @jonasenander ow.ly/h4lK50ITJlA
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