The Rullo Lab
@RulloLab
Student-run Twitter for the Rullo Lab @McMasterU, located in the Michael DeGroote Centre for Learning and Discovery (MDCL)🧪 Find us at: http://rullolab.com
Very excited to share our group's latest research, published in @NatureComms, titled 'Mimicry of molecular glues using dual covalent chimeras'! @LabRullo Check out the full publication here: nature.com/articles/s4146…
Incredibly proud of @RulloLab members Karolina Krygier, Tomas Frankovich and Anjalee Wijetunge for brilliant presentations at @qomsboc 2024!
@LabRullo was cited in an independent blog on @ScienceMagazine website written by Derek Lowe titled “Induced Proximity in the Lab and in the Clinic”. He is cited at the 4th link. 🔗science.org/content/blog-p… Congratulations! 👏🥳 @RulloLab @machealthsci @MacDeptMed
Covalent bispecific molecules to engage tumor-immune proximity @LabRullo doi.org/10.1016/j.omto…
Brilliant contribution by @DASpiegel256 and co workers to induced proximity
Bifunctional Molecules That Induce Both Targeted Degradation and Transcytosis of Extracellular Proteins in Brain Cells | Journal of the American Chemical Society @Yale @YaleChem #Targeted #Degradation #Transcytosis #BrainCells #Proteins #Extracellular pubs.acs.org/doi/10.1021/ja…
Congratulations to Sandra for being named CDCR’s trainee of the month!
Beautiful oxaziridine based oxidative approach to tryptophan labeling ! @christhechang and toste labs nature.com/articles/s4158…
Restricted Rotational Flexibility of the C5α-Methyl-Substituted Carbapenem NA-1-157 Leads to Potent Inhibition of the GES-5 Carbapenemase dlvr.it/T4YBjx
A beautifully written comprehensive review on the use of proximity induced chemistry to generate novel protein therapeutics by @Han_Xiao2016 cell.com/cell-chemical-…
Subunits of an E3 Ligase Complex as Degrons for Efficient Degradation of Cytosolic, Nuclear, and Membrane Proteins | ACS Synthetic Biology pubs.acs.org/doi/10.1021/ac…
Excited to present our work in covalent bifunctionals, for inducing cell-cell proximity in immunology ! #Covalent #proximity trccc.org/annual-meeting
trccc.org
Annual Meeting | TRCCC
Annual Meeting | TRCCC
Excited to return to beautiful Boston this Tuesday and see great colleagues working in covalent drug development and proximity inducing molecules! covalent-drug-discovery.com/whats-on/speak…
Join us tomorrow for our Work in Progress Seminar!
Check out our newest publication featuring @BenjaminLake15 ! Congratulations!
Happy to share our most recent contribution coupling covalency with carbohydrate binding for immune proximity induction. pubs.acs.org/doi/full/10.10…
Join us tomorrow for WIP, featuring Annika Yardy from the Larche lab and Danielle Libera from the @jfekoenig @Jordana_Lab!
A must read
Exploration of the Tunability of BRD4 Degradation by DCAF16 Trans-labelling Covalent Glues dlvr.it/SxGnd3
Congratulations to Eden for an amazing Ph.D. comprehensive exam! Eden passed with distinction, and the entire Rullo lab is extremely proud. Well-deserved 🥳
Congratulations Sissi on a strong Master’s Defence! Wishing you all the best in your future endeavours 🎉🥳👏
Brilliant covalent chimeric technology developed by @ChoudharyLab to chemically modulate protein phosphorylation pubs.acs.org/doi/10.1021/ac…
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