내가 좋아할 만한 콘텐츠
📢Last weeks #immunometabolism discoveries @Bims_BiomedNews ⬇️⬇️⬇️ biomed.news/bims-imicid/20… Many highlights inside! incl. TRAF6 integrates innate immune signals to regulate glucose homeostasis via Parkin-dependent and Parkin-independent mitophagy
It was a great pleasure to be invited to the @MyMitoMission annual meet-up this past weekend. A wonderful community trying to make things better for #mitochondrial_disease. I took part in a panel discussion, did an interview, did some #mitochondria origami and had lots of fun 🤩
Fantastic opportunity to learn from a real expert in mitochondrial biology and work with an all round great guy! Don't miss out!
I have three exciting, interdisciplinary mitochondria-focused PhD projects open as part of the MRC DTP or Bicentenary studentship programmes at the University of Manchester. For more information, see: findaphd.com/phds/?Keywords…
Mapping Structural Aging across Human Tissues reveals tissue-specific trajectories, coordinated deterioration and genetic determinants biorxiv.org/content/10.110…
Listen here for an interview I did on "Climbing the Immune Ladder: Steps for Success in Science". We discuss immunology, kindness and mentorship, navigating scientific challenges, identifying high-impact research questions, and our evolving careers open.spotify.com/episode/00rJPD…
MAPL regulates gasdermin-mediated release of mtDNA from lysosomes to drive pyroptotic cell death nature.com/articles/s4155…
Varicella-zoster virus reactivation (shingles) is linked to an increased risk of dementia, based on health records of >100 million people in the US, adding to many other studies demonstrating this link. Vaccination reduces this risk. #Alzheimer #Herpes nature.com/articles/s4159…
#DAMPsPower! Balachandran, Yin &co show @Nature that upon influenza #IAV or herpes #HSV1 virus infection, ZBP1 induces cell death by sensing #host-derived endogenous retroelement Z-RNAs produced in response to virulence factors! nature.com/articles/s4158…
Quantitative cellular characterization of extracellular mitochondria uptake and delivery #mitochondria #transfer doi.org/10.1038/s41467…
Metabolic profiling reveals channeled de novo pyrimidine and purine biosynthesis fueled by mitochondrially generated aspartic acid in cancer cells nature.com/articles/s4146…
#WeekendRead! #MomIsAlwaysMom! #EveryCellIsAnImmuneCell! Serhan, Gaudenzio &co show @Nature that elevated corticosterone in stressed moms alters #skin mast cells & mechanosensing #neurons causing fetal immunedysregulation & eczema after birth. doi.org/10.1038/s41586…
HEBP2-governed glutamine competition between tumor and macrophages dictates immunotherapy efficacy in triple-negative breast cancer dlvr.it/TNcTW4
T cell cholesterol transport links intestinal immune responses to dietary lipid absorption | Science science.org/doi/10.1126/sc…
Time to talk mitochondria and test out the origami #mitochondria With @mymitomission. Thanks to the @LJMUPharmBioSci #biochemistry students who constructed the mitochondria and ATP synthase @OrigamiCells
Our new work in @Cell_Metabolism by @ArtemAKhan describes three new SLC transporters, including SLC25A45, a mitochondrial transporter for methylated amino acids that is essential for carnitine synthesis and fasting adaptation. @RockefellerUniv cell.com/cell-metabolis…
Excited to share our work on discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine biosynthesis. @Cell_Metabolism @RockefellerUniv cell.com/cell-metabolis…
Idorn, Paludan et al. @AarhusUni characterize a mouse strain harboring a mutation found in a herpes simplex encephalitis patient. Defective IFN-driven antiviral responses led to hyperactivation of #inflammation, contributing to disease development. hubs.la/Q03N5vds0
The skin doesn’t just heal, it remembers. This Review Article explores how repeated microbial encounters, like with #Staphylococcus aureus, can “train” the skin’s immune system for faster, stronger responses. elifesciences.org/articles/10668…
Online Now: SLC25A45 is required for mitochondrial uptake of methylated amino acids and de novo carnitine biosynthesis dlvr.it/TNbfDK
Out Now! Mycobacterium tuberculosis-derived linoleic acid increases regulatory T cell function to promote bacterial survival within macrophages bit.ly/3J2yQIm #Mycobacterium #Tuberculosis #LinoleicAcid
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내가 좋아할 만한 콘텐츠
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Bims: Biomed News
@Bims_BiomedNews -
Jeff Rathmell
@JeffRathmell -
Lydia Lynch
@lynchielydia -
Tristram Ryan
@tristramryan -
HoLab
@PCHo_Lab -
Jan Van den Bossche Lab
@immunometlab -
Delgoffe Lab
@DelgoffeLab -
Nature Metabolism
@NatMetabolism -
BSI Immunometabolism
@BSI_immunomet -
Muñoz-Pinedo/Ernest Nadal - PRETT lab
@apoptosislab -
Natalie Niemi
@nieminm -
Nature Aging
@NatureAging -
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@DrRGJonesLab -
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@RubenQC_Lab -
Stanford Center on Longevity
@LongevityCenter
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