The Gruber Lab
@TheGruberLab
Targeting Cancer with Synthetic Biology, Controlling Epigenome, Exploring VISTA || http://gruberlabutsw.org
قد يعجبك
Excited to share a new cancer suppression pathway: Our recent study reveals that a tiny, four-amino-acid motif inside VISTA directly blocks growth receptor signaling in cancer cells—inducing tumor suppression from within.aacrjournals.org/cancerres/arti…
We had a full house for the final WIPs of two of our senior grad students: @mikayla_eppert from @bsabari lab on gene activation in condensates and HB Kim from @KrausWL lab on dose-dependent effects of estrogen on genomic regulation in breast cancer
We are looking for research technicians and postdocs. If you’re interested in genomics and/or reproductive biology. Please reach out! jobs.utsouthwestern.edu/job/21454219/r…
Super excited to share our new study from the @JD_Buenrostro Lab in @Nature! We developed a computational method for tracking transcription factor and nucleosome binding using single-cell ATAC-seq and deep learning. Paper: nature.com/articles/s4158…
More than 40 percent of #postdocs leave academia. Those who landed a coveted faculty position were more likely to have had a highly cited paper, changed their research topic between their #PhD and postdoc, or moved abroad after receiving their doctorate. pnas.org/doi/10.1073/pn……
5,562 proteins were found to have tissue-specific enrichment across 32 human tissues. ◼️ The majority of them (3,088) are enriched at the protein but not RNA level. 🧠 The brain hosts the largest number of proteins that are only enriched at the protein level but not RNA level.
Nucleosomal asymmetry shapes histone mark binding and promotes poising at bivalent domains sciencedirect.com/science/articl…
Join @postingThruPhD at poster No. B662 to see how @UTSWMedCenter engineers are developing animal cells that can photosynthesize! After, come meet our staff, students, and researchers at exhibitor booth 712! #cellbio2024 @ASCBiology
The fall season of Fragile Nucleosome seminar is back! On Sept. 13th, we will feature @snaqvi1990 and @harrisonflylab. Please join us with the following link:harvard.zoom.us/webinar/regist…
Octopuses edit their own genetic code to adapt to colder water newscientist.com/article/237752…
First manuscript from the Gruber lab is out now pubs.acs.org/doi/full/10.10……, where we made an acetyl-click screening platform to find out the inhibitors for HAT1 (A master regulator in cancer biology)
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